7181-73-9|Bephenium|Bephenium|-范德生物科技公司

Bephenium

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names：
Bephenium
CAS号：
7181-73-9
MDL Number：
MF(分子式)： C17H22NO MW(分子量)： 256.36
EINECS:230-546-7 Reaxys Number:
Pubchem ID:19667 Brand:BIOFOUNT

Bephenium(7181-73-9)又称为羟萘酸苄酚宁或灭虫宁：灭虫宁为黄绿色结晶性粉末。熔点170-171℃，略溶于乙醇，不溶于不和乙醚。无臭，味苦。Bephenium是一种驱虫药。Bephenium也是B型乙酰胆碱受体激活剂。

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
YZM000848-500mg	500mg	>95%	¥ 810.00	¥ 810.00		Backorder	- +	¥ 0.00
YZM000848-100mg	100mg	>95%	¥ 488.00	¥ 488.00		Backorder	- +	¥ 0.00

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询价

中文别名	Bephenium(7181-73-9)
英文别名	Bephenium,7181-73-9
CAS号	7181-73-9
SMILES	C[N+](CCOC1=CC=CC=C1)(C)CC2=CC=CC=C2
Inchi	InChI=1S/C17H22NO/c1-18(2,15-16-9-5-3-6-10-16)13-14-19-17-11-7-4-8-12-17/h3-12H,13-15H2,1-2H3/q+1
InchiKey	AVWWVJUMXRXPNF-UHFFFAOYSA-N
分子式 Formula	C17H22NO
分子量 Molecular Weight	256.36
闪点 FP	No data available
熔点 Melting point	170-171℃
沸点 Boiling point	No data available
Polarizability极化度	No data available
密度 Density	No data available
蒸汽压 Vapor Pressure	No data available
溶解度Solubility
性状	黄绿色结晶性粉末
储藏条件 Storage conditions	请根据产品建议的存储条件进行存储,Please store the product under the recommended condition sin the description.

Bephenium(7181-73-9)毒性测试：

生物	测试类型	路线	报告剂量（标准化剂量）	影响	参考
mouse	LD50	oral	7880 mg/kg (7880 mg/kg)		British Journal of Pharmacology and Chemotherapy., 17(321), 1961 [PMID:13873487]

Bephenium(7181-73-9)实验注意事项：
1.实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害
3.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染

Bephenium(7181-73-9)Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

Tag:Bephenium(7181-73-9),Bephenium试剂,Bephenium抑制剂,Bephenium的纯度,Bephenium的作用,Bephenium的合成,Bephenium的厂家,Bephenium的价格,Bephenium的MSDS,Bephenium的生产,Bephenium的外观,Bephenium的含量,Bephenium的溶解度

产品说明	Bephenium(7181-73-9)是一种驱虫药。Bephenium也是B型乙酰胆碱受体激活剂。
Introduction	Bephenium (7181-73-9) is an anthelmintic. Bephenium is also a type B acetylcholine receptor activator.
Application1	Bephenium(7181-73-9)为广谱抗肠虫产品，对钩虫、蛔虫、鞭虫病均有效。
Application2
Application3

警示图
危险性	warning
危险性警示	Not available
安全声明	H303吞入可能有害+H313皮肤接触可能有害+H2413吸入可能对身体有害
安全防护	P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P2393获得医疗建议/护理
备注	实验过程中防止吸入、食入，做好安全防护

Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors(2012-06-01,PMID号:22526556)

Activity of novel nicotinic anthelmintics in cut preparations of Caenorhabditis elegans(2011-03-01,PMID号:21195075)

The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits

Pharmacology of N-, L-, and B-subtypes of nematode nAChR resolved at the single-channel level in Ascaris suum

Contractile activity and motility responses of the dog heartworm Dirofilaria immitis to classical anthelmintics and other compounds

Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors.
Charvet CL1, Robertson AP, Cabaret J, Martin RJ, Neveu C. Invert Neurosci. 2012 Jun;12(1):43-51. doi: 10.1007/s10158-012-0130-0. Epub 2012 Apr 24.
Abstract:Acetylcholine receptors (AChRs) are pentameric ligand-gated ion channels involved in the neurotransmission of both vertebrates and invertebrates. A number of anthelmintic compounds like levamisole and pyrantel target the AChRs of nematodes producing spastic paralysis of the worms. The muscle AChRs of nematode parasites fall into three pharmacological classes that are preferentially activated by the cholinergic agonists levamisole (L-type), nicotine (N-type) and bephenium (B-type), respectively. Despite a number of studies of the B-type AChR in parasitic species, this receptor remains to be characterized at the molecular level. Recently, we have reconstituted and functionally characterized two distinct L-AChR subtypes of the gastro-intestinal parasitic nematode Haemonchus contortus in the Xenopus laevis oocyte expression system by providing the cRNAs encoding the receptor subunits and three ancillary proteins (Boulin et al.

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