3463-92-1|番木瓜碱|Carpaine|-范德生物科技公司

番木瓜碱

NMR下载 COA and HPLC MSDS下载
names：
Carpaine
CAS号：
3463-92-1
MDL Number：
MF(分子式)： C28H50N2O4 MW(分子量)： 478.71
EINECS:222-414-2 Reaxys Number:
Pubchem ID:442630 Brand:BIOFOUNT

番木瓜碱(3463-92-1,Carpaine)是一种生物碱，是木瓜叶的主要成分，番木瓜碱已显示出具有心血管作用和植物代谢产物的作用。番木瓜碱是生物碱和大环糖苷。

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
YZM000832-5mg	5mg	>95%	¥ 0.00	¥ 0.00		Backorder	- +	¥ 0.00
YZM000832-1mg	1mg	>95%	¥ 0.00	¥ 0.00		Backorder	- +	¥ 0.00

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中文别名	番木瓜碱(3463-92-1,Carpaine);番木瓜鹼
英文别名	Carpaine(3463-92-1);(+)-Carpaine
CAS号	3463-92-1
SMILES	O=C(CCCCCCC[C@@]1([H])N[C@@H](C)[C@@](CC1)([H])O2)O[C@](CC3)([H])[C@H](C)N[C@]3([H])CCCCCCCC2=O
Inchi	InChI=1S/C28H50N2O4/c1-21-25-19-17-23(29-21)13-9-5-3-8-12-16-28(32)34-26-20-18-24(30-22(26)2)14-10-6-4-7-11-15-27(31)33-25/h21-26,29-30H,3-20H2,1-2H3/t21-,22-,23+,24+,25-,26-/m0/s1
InchiKey	AMSCMASJCYVAIF-QCVMBYIASA-N
分子式 Formula	C28H50N2O4
分子量 Molecular Weight	478.71
闪点 FP	353.0±31.5°C
熔点 Melting point	119-120°C
沸点 Boiling point	660.0±55.0 °C at 760 mmHg
Polarizability极化度	53.8±0.5 10-24cm3
密度 Density	1.0±0.1 g/cm3
蒸汽压 Vapor Pressure	0.0±2.0 mmHg at 25°C
溶解度Solubility
性状	Solid
储藏条件 Storage conditions	存放在阴凉干燥处，短期（数天至数周）在0-4℃，长期（数月至数年）在-20℃。

番木瓜碱(3463-92-1,Carpaine)实验注意事项：
1.实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害
3.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染

Carpaine(3463-92-1) Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

Tag:番木瓜碱(3463-92-1,Carpaine),番木瓜碱试剂,番木瓜碱抑制剂,番木瓜碱的纯度,番木瓜碱的生产,番木瓜碱的合成,番木瓜碱的厂家,番木瓜碱的价格,番木瓜碱的外观,番木瓜碱的溶解度,番木瓜碱的作用,番木瓜碱的MSDS,番木瓜碱的含量

产品说明	番木瓜碱(3463-92-1,Carpaine)是一种有效的具有抗血小板减少活性的生物碱，在维持血小板数目方面表现出强烈的活性，无急性毒性。
Introduction	Carpaine (3463-92-1,番木瓜碱) is an effective alkaloid with anti-thrombocytopenic activity. It exhibits strong activity in maintaining the number of platelets without acute toxicity.
Application1
Application2
Application3

警示图
危险性	warning
危险性警示	Not available
安全声明	H303吞入可能有害+H313皮肤接触可能有害+H2413吸入可能对身体有害
安全防护	P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P2393获得医疗建议/护理
备注	实验过程中防止吸入、食入，做好安全防护

Anwendung der Massenspektrometrie zur Strukturaufkl?urung von Alkaloiden, 5. Mitt.: Die Struktur des Carpains(Monatshefte für Chemie und verwandte Teile anderer Wissenschaften,1964)

Carpaine: An alkaloid of Carica papaya—its chemistry and pharmacology(Economic Botany,1971)

Phytochemical examination of the leaves of carica papaya L.(Economic Botany,1956)

Five decades in the study of natural products(Journal of Chemical Sciences,2002)

Molecular docking studies of phytochemicals against trehalose–6–phosphate phosphatases of pathogenic microbes(Beni-Suef University Journal of Basic and Applied Sciences,2020)

Weak C-H…O hydrogen bonds in alkaloids: An overview
Abstract:An overview of general classification scheme, medicinal importance and crystal structure analysis with emphasis on the role of hydrogen bonding in some alkaloids is presented in this paper. The article is based on a general kind of survey while crystallographic analysis and role of hydrogen bonding are limited to only those alkaloids whose three-dimensional structure has been reported by us. The C-H…O hydrogen bonding in the solid state in alkaloids has been found to be predominant and this observation makes the role of hydrogen bonding in organic molecular assemblies very important.

Evaluation of anti-dengue activity of Carica papaya aqueous leaf extract and its role in platelet augmentation
Abstract:Dengue disease is characterized by a marked decrease in platelet count, which is life threatening. In the present study, we investigated the antiviral activity of an aqueous extract of Carica papaya leaves (PLE) against dengue virus (DENV) and its effect on platelet augmentation. The anti-dengue activity of PLE in DENV-infected THP-1 cells was examined by immunoblotting and flow cytometry. The effect of PLE on erythrocyte damage was investigated using hemolytic and anti-hemolytic assays. Virus-infected THP-1 cells were assayed for IFN-α secretion. The effect of PLE on platelet augmentation in rats with cyclophosphamide-induced thrombocytopenia was also investigated. The platelet count of blood from the retro-orbital plexus of rats was determined on the 1st, 4th, 7th, 11th and 14th day of study. On the 14th day, the rats were sacrificed for histopathological examination of the liver, kidney and spleen. Plasma of thrombocytopenic rats was tested for thrombopoietin (TPO) and IL-6 secretion. The data suggest that PLE significantly decreases the expression of the envelope and NS1 proteins in DENV-infected THP-1 cells. A marked decrease in intracellular viral load upon PLE treatment confirmed its antiviral activity. This also resulted in a significant decrease in erythrocyte damage and hydrogen-peroxide-induced lipid peroxidation. A significant increase in the number of platelets was found in thrombocytopenic rats treated with PLE, along with an increase in IL-6 and TPO levels. These findings suggest that PLE can potentially be used as an antiviral agent, as it helps in platelet augmentation and exhibits antiviral activity against DENV.

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