酒石酸噻吩嘧啶

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names：
Pyrantel tartrate
CAS号：
33401-94-4
MDL Number：
MF(分子式)： C15H20N2O6S MW(分子量)： 356.39
EINECS:251-501-8 Reaxys Number:33401-94-4
Pubchem ID:5145916 Brand:BIOFOUNT

酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4):牲畜的广谱驱虫药。

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
YZM000792-500mg	500mg	99.58%	¥ 911.00	¥ 911.00		2-3天	- +	¥ 0.00
YZM000792-100mg	100mg	99.58%	¥ 341.25	¥ 341.25		2-3天	- +	¥ 0.00

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询价

中文别名	酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)
英文别名	Pyrantel tartrate(酒石酸噻吩嘧啶,33401-94-4)
CAS号	33401-94-4
SMILES	CN1CCCN=C1/C=C/C2=CC=CS2.O=C(O)[C@H](O)[C@@H](O)C(O)=O
Inchi	InChI=1S/C11H14N2S.C4H6O6/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10;5-1(3(7)8)2(6)4(9)10/h2,4-6,9H,3,7-8H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/b6-5+;/t;1-,2-/m.1/s1
InchiKey	VWRCYAZJKNPEQR-NIEARKAZSA-N
分子式 Formula	C15H20N2O6S
分子量 Molecular Weight	356.39
闪点 FP	No data available
熔点 Melting point	148-150°
沸点 Boiling point	No data available
Polarizability极化度	No data available
密度 Density	No data available
蒸汽压 Vapor Pressure	No data available
溶解度Solubility	生物体外In Vitro:DMSO溶解度≥ 34 mg/mL(95.40 mM)*"≥" means soluble可溶, but saturation unknown溶解度未知.
性状	固体粉末,Power
储藏条件 Storage conditions	-20°C 3 years年 4°C 2 years年 / In solvent溶液中:-80°C 6 months月 -20°C 1 month月

酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)毒性

生物	测试类型	路线	报告剂量（标准化剂量）	影响	参考
cattle	LD	unreported	> 200mg/kg (200mg/kg)		Australian Veterinary Journal. Vol. 46, Pg. 297, 1970.
mouse	LD50	intravenous	2220ug/kg (2.22mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
mouse	LD50	oral	123mg/kg (123mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
mouse	LD50	subcutaneous	> 25mg/kg (25mg/kg)		Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 305, 1971.
rat	LD50	oral	170mg/kg (170mg/kg)		Australian Veterinary Journal. Vol. 46, Pg. 297, 1970.

酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)实验注意事项：
1.实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害
3.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

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产品说明	酒石酸噻吩嘧啶(Pyrantel tartrate,33401-94-4)是一种杀线虫噻吩
Introduction	Pyrantel tartrate(酒石酸噻吩嘧啶,33401-94-4) is an antinematodal thiophene
Application1
Application2
Application3

警示图
危险性	warning
危险性警示	Not available
安全声明	H303吞入可能有害+H313皮肤接触可能有害+H2413吸入可能对身体有害
安全防护	P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P2393获得医疗建议/护理
备注	实验过程中防止吸入、食入，做好安全防护

Parasite field study in central Kentucky on thoroughbred foals (born in 2004) treated with pyrantel tartrate daily and other parasiticides periodically Parasitology Research 2006/PMID: 17013652

Serum Strongylus vulgaris-specific antibody responses to anthelmintic treatment in naturally infected horses Parasitology Research 2014/PMID: 25358238

A light and electron microscopic study on the synergistic effect of pyrantel and the febantel metabolite febendazole on adult Toxocara canis in vitro Parasitology Research 2003/PMID: 12684883

Diagnosis and control of anthelmintic-resistant Parascaris equorum Parasites & Vectors 2009/PMID: 19778469

Transient effects of levamisole on Brugia malayi microfilariae Invertebrate Neuroscience 2015/PMID: 26187649

Activity of selected antioxidative enzymes in rats exposed to dimethoate and pyrantel tartrate

Abstract

This study presents the results of research concerning the effect of single and combined application of pyrantel tartrate and dimethoate on selected antioxidative enzymes: catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx), in rat erythrocytes. Pyrantel tartrate was applied twice, at a dose of 85 mg/kg bw at a two week interval, i.e. on day 14 and 28 of the experiment, orally, in a water solution with a stomach tube. Dimethoate was administered with drinking water for 28 days at a dose of 25 mg/kg bw/day. It was found that pyrantel tartrate caused only small changes in the activity of the antioxidative enzymes under analysis. Subchronic exposure of rats to dimethoate caused a significant increase in the activity of CAT, SOD and GPx in erythrocytes, indicating the existence of strong oxidative stress. In combined intoxication, no significant effects of administering pyrantel tartrate on the activity of CAT, SOD and GPx was found in animals poisoned with dimethoate. The profile of changes was similar to that observed in rats exposed only to the organophosphorus insecticide. This may indicate a lack of interaction between the compounds used in the experiment.

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