10054-05-4|Ethambutol, (R,R)-|2,2'-(ethane-1,2-diylbis(azanediyl))bis(butan-1-ol)|-范德生物科技公司

Ethambutol, (R,R)-

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names：
2,2'-(ethane-1,2-diylbis(azanediyl))bis(butan-1-ol)
CAS号：
10054-05-4
MDL Number：
MF(分子式)： C10H24N2O2 MW(分子量)： 204.31
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Ethambutol, (R,R)-
英文别名	Ethambutol, (R,R)-; L-Ethambutol;
CAS号	10054-05-4
SMILES	CCC(NCCNC(CC)CO)CO
Inchi	InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3
InchiKey	AEUTYOVWOVBAKS-UHFFFAOYSA-N
分子式 Formula	C10H24N2O2
分子量 Molecular Weight	204.31
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Ethambutol, (R,R)-(CAS:10054-05-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Ethambutol, (R,R)- is a medication primarily used to treat tuberculosis. It is usually given in combination with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. It may also be used to treat Mycobacterium avium complex, and Mycobacterium kansasii.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Srivastava S, Gumbo T. Clofazimine for the treatment of Mycobacterium kansasii. Antimicrob Agents Chemother. 2018 May 29. pii: AAC.00248-18. doi: 10.1128/AAC.00248-18. [Epub ahead of print] PubMed PMID: 29844047.

[2]Vaghela JH, Nimbark V, Barvaliya M, Mehta H, Chavada B. Antituberculosis Drug-Induced Fixed Drug Eruption: A Case Report. Drug Saf Case Rep. 2018 May 21;5(1):23. doi: 10.1007/s40800-018-0086-z. PubMed PMID: 29785553; PubMed Central PMCID: PMC5962523.

[3] Lee JY, Han J, Seo JG, Park KA, Oh SY. Diagnostic value of ganglion cell-inner plexiform layer for early detection of ethambutol-induced optic neuropathy. Br J Ophthalmol. 2018 Apr 26. pii: bjophthalmol-2018-312063. doi: 10.1136/bjophthalmol-2018-312063. [Epub ahead of print] PubMed PMID: 29699978.

[4] Rezaei F, Haeili M, Fooladi AI, Feizabadi MM. High Resolution Melting Curve Analysis for Rapid Detection of Streptomycin and Ethambutol Resistance in Mycobacterium tuberculosis. Maedica (Buchar). 2017 Dec;12(4):246-257. PubMed PMID: 29610587; PubMed Central PMCID: PMC5879581.

[5] Fregonese F, Ahuja SD, Akkerman OW, Arakaki-Sanchez D, Ayakaka I, Baghaei P, Bang D, Bastos M, Benedetti A, Bonnet M, Cattamanchi A, Cegielski P, Chien JY, Cox H, Dedicoat M, Erkens C, Escalante P, Falzon D, Garcia-Prats AJ, Gegia M, Gillespie SH, Glynn JR, Goldberg S, Griffith D, Jacobson KR, Johnston JC, Jones-López EC, Khan A, Koh WJ, Kritski A, Lan ZY, Lee JH, Li PZ, Maciel EL, Galliez RM

6: Rahgozar N, Bakhshi Khaniki G, Sardari S. Evaluation of Antimycobacterial and Synergistic Activity of Plants Selected Based on Cheminformatic Parameters. Iran Biomed J. 2018 Mar 7. [Epub ahead of print] PubMed PMID: 29510602.7: Battini S, Mannava MKC, Nangia A. Improved Stability of Tuberculosis Drug Fixed-Dose Combination Using Isoniazid-Caffeic Acid and Vanillic Acid Cocrystal. J Pharm Sci. 2018 Jun;107(6):1667-1679. doi: 10.1016/j.xphs.2018.02.014. Epub 2018 Feb 17. PubMed PMID: 29462633.8: Sieniawska E, Sawicki R, Swatko-Ossor M, Napiorkowska A, Przekora A, Ginalska G, Augustynowicz-Kopec E. The Effect of Combining Natural Terpenes and Antituberculous Agents against Reference and Clinical Mycobacterium tuberculosis Strains. Molecules. 2018 Jan 15;23(1). pii: E176. doi: 10.3390/molecules23010176. PubMed PMID: 29342972.9: Patel N, Jagannath K, Vora A, Patel M, Patel A. A Randomized, Controlled, Phase III Clinical Trial to Evaluate the Efficacy and Tolerability of Risorine with Conventional Rifampicin in the Treatment of Newly Diagnosed Pulmonary Tuberculosis Patients. J Assoc Physicians India. 2017 Sep;65(9):48-54. PubMed PMID: 29313577.10: An H, Wang Z, Chen H, Wang T, Wang X, Liu L, Liu X, Xu J, He L, Zhang K, Zhang H, Liu X. Clinical efficacy of short-course chemotherapy combined with topical injection therapy in treatment of superficial lymph node tuberculosis. Oncotarget. 2017 Nov 18;8(66):109889-109893. doi: 10.18632/oncotarget.22492. eCollection 2017 Dec 15. PubMed PMID: 29299116; PubMed Central PMCID: PMC5746351.1

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