93287-54-8|Cgp 29287|Cgp 29287|-范德生物科技公司

Cgp 29287

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names：
Cgp 29287
CAS号：
93287-54-8
MDL Number：
MF(分子式)： C72H110N20O15 MW(分子量)： 1495.79
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
FMK13304-100mg	100mg	>98%	¥ 0.00	¥ 0.00		Get quote	- +	¥ 0.00

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中文别名	methyl N2-((3S,4S)-4-((S)-2-((S)-2-((S)-1-(((benzyloxy)carbonyl)-L-arginyl-L-arginyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-3-(1H-imidazol-4-yl)propanamido)-3-hydroxy-6-methylheptanoyl)-L-isoleucyl-L-histidyl-N6-(tert-butoxycarbonyl)-L-lysinate
英文别名	Cgp 29287; Cgp-29287; Cgp29287; Cgp-29,287; Cgp 29,287; Cgp29,287;
CAS号	93287-54-8
Inchi	InChI=1S/C72H110N20O15/c1-9-44(4)59(65(100)89-55(36-48-39-78-42-83-48)62(97)85-51(67(102)105-8)25-16-17-29-81-70(103)107-72(5,6)7)91-58(94)37-57(93)52(33-43(2)3)86-63(98)54(35-47-38-77-41-82-47)87-61(96)53(34-45-21-12-10-13-22-45)88-64(99)56-28-20-32-92(56)66(101)50(27-19-31-80-69(75)76)84-60(95)49(26-18-30-79-68(73)74)90-71(104)106-40-46-23-14-11-15-24-46/h10-15,21-24,38-39,41-44,49-57,59,93H,9,16-20,25-37,40H2,1-8H3,(H,77,82)(H,78,83)(H,81,103)(H,84,95)(H,85,97)(H,86,98)(H,87,96)(H,88,99)(H,89,100)(H,90,104)(H,91,94)(H4,73,74,79)(H4,75,76,80)/t44-,49-,50-,51-,52-,53-,54-,55-,56-,57-,59-/m0/s1
InchiKey	DLAHCJHYEAZDLE-VRYQDWSQSA-N
分子式 Formula	C72H110N20O15
分子量 Molecular Weight	1495.79
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Cgp 29287(CAS:93287-54-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Cgp 29287 is a primate-specific renin inhibitor with prolonged duration of action.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Samani NJ, Cumin F, Kelly M, Wood JM. Expression of components of the RAS during prolonged blockade at different levels in primates. Am J Physiol. 1994 Oct;267(4 Pt 1):E612-9. PubMed PMID: 7943312.

[2]Humke U, Levens N, Wood J, Hofbauer K. Responses to renin inhibition in conscious primates. Am J Physiol. 1991 Jul;261(1 Pt 2):F179-86. PubMed PMID: 1907105.

[3] Nussberger J, Brunner DB, Waeber B, Brunner HR. In vitro renin inhibition to prevent generation of angiotensins during determination of angiotensin I and II. Life Sci. 1988;42(17):1683-8. PubMed PMID: 2835564.

[4] de Gasparo MM, Wood JM, Heusser CH. Mechanism of inhibition of human renin by monoclonal antibodies. Hypertension. 1988 Mar;11(3):209-16. PubMed PMID: 3280480.

[5] Wood JM, Jobber RA, Baum HP, Hofbauer KG. Comparison of chronic inhibition of renin and converting enzyme in the marmoset. Clin Exp Hypertens A. 1987;9(2-3):337-43. PubMed PMID: 3038392.

6: Wood JM, Baum HP, Carleton J, Dzau VJ. Inhibition of renin-like activity in marmoset tissues by the renin inhibitor CGP 29 287. J Hypertens Suppl. 1987 Jul;5(2):S67-9. PubMed PMID: 3116182.7: Wood JM, Gulati N, Forgiarini P, Fuhrer W, Hofbauer KG. Effects of a specific and long-acting renin inhibitor in the marmoset. Hypertension. 1985 Sep-Oct;7(5):797-803. PubMed PMID: 3928488.8: Wood JM, Baum HP, Forgiarini P, Gulati N, Jobber RA, Neisius D, Hofbauer KG. Haemodynamic effects of acute and chronic renin inhibition in marmosets. J Hypertens Suppl. 1989 Apr;7(2):S37-42. PubMed PMID: 2547039.9: Wood JM, Baum HP, Jobber RA, Neisius D. Sustained reduction in blood pressure during chronic administration of a renin inhibitor to normotensive marmosets. J Cardiovasc Pharmacol. 1987;10 Suppl 7:S96-8. PubMed PMID: 2485073.10: Wood JM, Jobber RA, Baum HP, de Gasparo M, Nussberger J. Biochemical effects of prolonged renin inhibition in marmosets. J Hypertens. 1989 Aug;7(8):615-8. PubMed PMID: 2681408.1

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