28526-44-5|Siphonaxanthin|(3E,5E,7E,9E,11E,13E,15E,17E)-3-(hydroxymethyl)-1-(4-hydroxy-2,6,6-trimethylcyclohexen-1-yl)-18-(4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl)-7,12,16-trimethyloctadeca-3,5,7,9,11,13,15,17-octaen-2-one|-范德生物科技公司

Siphonaxanthin

NMR下载 COA and HPLC MSDS下载
names：
(3E,5E,7E,9E,11E,13E,15E,17E)-3-(hydroxymethyl)-1-(4-hydroxy-2,6,6-trimethylcyclohexen-1-yl)-18-(4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl)-7,12,16-trimethyloctadeca-3,5,7,9,11,13,15,17-octaen-2-one
CAS号：
28526-44-5
MDL Number：
MF(分子式)： C40H56O4 MW(分子量)： 600.884
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	(3E,5E,7E,9E,11E,13E,15E,17E)-3-(hydroxymethyl)-1-(4-hydroxy-2,6,6-trimethylcyclohexen-1-yl)-18-(4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl)-7,12,16-trimethyloctadeca-3,5,7,9,11,13,15,17-octaen-2-one
英文别名	Siphonaxanthin
CAS号	28526-44-5
SMILES	O=C(/C(CO)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(C)=CC(O)CC1(C)C)CC2=C(C)CC(O)CC2(C)C
Inchi	InChI=1S/C40H56O4/c1-28(16-12-17-30(3)20-21-36-31(4)22-34(42)25-39(36,6)7)14-10-11-15-29(2)18-13-19-33(27-41)38(44)24-37-32(5)23-35(43)26-40(37,8)9/h10-22,34-36,41-43H,23-27H2,1-9H3/b11-10+,16-12+,18-13+,21-20+,28-14+,29-15+,30-17+,33-19+
InchiKey	SUCKEYMKNGZJHK-LANKSYMZSA-N
分子式 Formula	C40H56O4
分子量 Molecular Weight	600.884
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Siphonaxanthin(CAS:28526-44-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Siphonaxanthin is a marine carotenoid from green algae that induces apoptosis in human leukemia (HL-60) cells.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Sugawara T, Ganesan P, Li Z, Manabe Y, Hirata T. Siphonaxanthin, a green algal carotenoid, as a novel functional compound. Mar Drugs. 2014 Jun 19;12(6):3660-8. doi: 10.3390/md12063660. Review. PubMed PMID: 24950294; PubMed Central PMCID: PMC4071595.

[2]Zheng J, Li Z, Manabe Y, Kim M, Goto T, Kawada T, Sugawara T. Siphonaxanthin, a Carotenoid From Green Algae, Inhibits Lipogenesis in Hepatocytes via the Suppression of Liver X Receptor α Activity. Lipids. 2018 Jan;53(1):41-52. doi: 10.1002/lipd.12002. Epub 2018 Feb 15. PubMed PMID: 29446839.

[3] Ganesan P, Noda K, Manabe Y, Ohkubo T, Tanaka Y, Maoka T, Sugawara T, Hirata T. Siphonaxanthin, a marine carotenoid from green algae, effectively induces apoptosis in human leukemia (HL-60) cells. Biochim Biophys Acta. 2011 May;1810(5):497-503. doi: 10.1016/j.bbagen.2011.02.008. Epub 2011 Mar 1. PubMed PMID: 21371530.

[4] Li ZS, Noda K, Fujita E, Manabe Y, Hirata T, Sugawara T. The green algal carotenoid siphonaxanthin inhibits adipogenesis in 3T3-L1 preadipocytes and the accumulation of lipids in white adipose tissue of KK-Ay mice. J Nutr. 2015 Mar;145(3):490-8. doi: 10.3945/jn.114.200931. Epub 2014 Dec 24. PubMed PMID: 25733464.

[5] Manabe Y, Takii Y, Sugawara T. Siphonaxanthin, a carotenoid from green algae, suppresses advanced glycation end product-induced inflammatory responses. J Nat Med. 2019 Aug 20. doi: 10.1007/s11418-019-01354-z. [Epub ahead of print] PubMed PMID: 31432315.

6: Wang W, Qin X, Sang M, Chen D, Wang K, Lin R, Lu C, Shen JR, Kuang T. Spectral and functional studies on siphonaxanthin-type light-harvesting complex of photosystem II from Bryopsis corticulans. Photosynth Res. 2013 Nov;117(1-3):267-79. doi: 10.1007/s11120-013-9808-3. Epub 2013 Mar 12. PubMed PMID: 23479128.7: Li ZS, Zheng JW, Manabe Y, Hirata T, Sugawara T. Anti-Obesity Properties of the Dietary Green Alga, Codium cylindricum, in High-Fat Diet-Induced Obese Mice. J Nutr Sci Vitaminol (Tokyo). 2018;64(5):347-356. doi: 10.3177/jnsv.64.347. PubMed PMID: 30381625.8: Ganesan P, Matsubara K, Ohkubo T, Tanaka Y, Noda K, Sugawara T, Hirata T. Anti-angiogenic effect of siphonaxanthin from green alga, Codium fragile. Phytomedicine. 2010 Dec 1;17(14):1140-4. doi: 10.1016/j.phymed.2010.05.005. Epub 2010 Jul 16. PubMed PMID: 20637577.9: Manabe Y, Ichihara M, Fukuda K, Tomonaga N, Li ZS, Yamanashi Y, Suzuki H, Takada T, Matsuo M, Sugawara T. Niemann-Pick C1-like 1 Promotes Intestinal Absorption of Siphonaxanthin. Lipids. 2019 Oct 1. doi: 10.1002/lipd.12194. [Epub ahead of print] PubMed PMID: 31574565.10: Akimoto S, Yokono M, Higuchi M, Tomo T, Takaichi S, Murakami A, Mimuro M. Solvent effects on excitation relaxation dynamics of a keto-carotenoid, siphonaxanthin. Photochem Photobiol Sci. 2008 Oct;7(10):1206-9. doi: 10.1039/b802658k. Epub 2008 Aug 6. PubMed PMID: 18846284.1

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