40757-80-0|Linoleoyl-coenzyme A|Coenzyme A, S-9,12-octadecadienoate-|-范德生物科技公司

Linoleoyl-coenzyme A

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names：
Coenzyme A, S-9,12-octadecadienoate-
CAS号：
40757-80-0
MDL Number：
MF(分子式)： C39H67N7O18P3S MW(分子量)： 1046.97
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Linoleoyl-coenzyme A
英文别名	Linoleoyl-coenzyme A; Coenzyme A, linoleoyl-;
CAS号	40757-80-0
SMILES	CCCCC/C=C/C/C=C/CCCCCCCC([O-])=O.SCCNC(CCNC([C@@H](C(C)(COP(O[P@](OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3N)O)OP(O)(O)=O)(O)=O)(O)=O)C)O)=O)=O
Inchi	InChI=1S/C21H36N7O16P3S.C18H32O2/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35);6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/p-1/b;7-6+,10-9+/t11-,14-,15-,16+,20-;/m1./s1
InchiKey	GISNRZPAZNWKHE-XFLCQTJPSA-M
分子式 Formula	C39H67N7O18P3S
分子量 Molecular Weight	1046.97
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Linoleoyl-coenzyme A(CAS:40757-80-0):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Linoleoyl-coenzyme A is a substrate used to investigate the specificity and kinetics of acyl-CoA lysophosphatidylcholine acyltransferase (LPCAT) and mitochondrial linoleoyl-coenzyme monolysocardiolipin acyltransferase-1 (MLCL AT-1).
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Taylor WA, Hatch GM. Identification of the human mitochondrial linoleoyl-coenzyme A monolysocardiolipin acyltransferase (MLCL AT-1). J Biol Chem. 2009 Oct 30;284(44):30360-7[1]doi: 10.1074/jbc.M109.048322. Epub 2009 Sep 8. PubMed PMID: 19737925; PubMed Central PMCID: PMC2781591.

[2]Taylor WA, Hatch GM. Purification and characterization of monolysocardiolipin acyltransferase from pig liver mitochondria. J Biol Chem. 2003 Apr 11;278(15):12716-21. Epub 2003 Feb 4. PubMed PMID: 12569106.

[3] Deutsch J, Grange E, Rapoport SI, Purdon AD. Isolation and quantitation of long-chain acyl-coenzyme A esters in brain tissue by solid-phase extraction. Anal Biochem. 1994 Aug 1;220(2):321-3. PubMed PMID: 7978274.

[4] Young AJ, Barker KL. Effect of estradiol and progesterone on long chain fatty acyl-coenzyme A levels in the rat uterus. Biochim Biophys Acta. 1991 Apr 17;1092(2):211-7. PubMed PMID: 2018788.

[5] Kawashima Y, Kozuka H. Regulation of palmitoyl-CoA chain elongation and linoleoyl-CoA chain elongation in rat liver microsomes and the differential effects of peroxisome proliferators, insulin and thyroid hormone. Biochim Biophys Acta. 1985 Mar 27;834(1):118-23. PubMed PMID: 3884049.

6: Okayasu T. [Purification and characterization of Linoleoyl-CoA desaturase from rat liver microsomes (author's transl)]. Hokkaido Igaku Zasshi. 1981 Jan;56(1):43-54. Japanese. PubMed PMID: 7262818.7: Taylor WA, Mejia EM, Mitchell RW, Choy PC, Sparagna GC, Hatch GM. Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation. PLoS One. 2012;7(11):e48628. doi: 10.1371/journal.pone.0048628. Epub 2012 Nov 9. PubMed PMID: 23152787; PubMed Central PMCID: PMC3494688.8: Ayyash M, Algahmi A, Gillespie J, Oelkers P. Characterization of a lysophospholipid acyltransferase involved in membrane remodeling in Candida albicans. Biochim Biophys Acta. 2014 Apr 4;1841(4):505-13. doi: 10.1016/j.bbalip.2013.12.015. Epub 2014 Jan 7. PubMed PMID: 24406902; PubMed Central PMCID: PMC4169218.9: Prasad MR, Nagi MN, Ghesquier D, Cook L, Cinti DL. Evidence for multiple condensing enzymes in rat hepatic microsomes catalyzing the condensation of saturated, monounsaturated, and polyunsaturated acyl coenzyme A. J Biol Chem. 1986 Jun 25;261(18):8213-7. PubMed PMID: 3722151.10: Retamal MA, Evangelista-Martínez F, León-Paravic CG, Altenberg GA, Reuss L. Biphasic effect of linoleic acid on connexin 46 hemichannels. Pflugers Arch. 2011 Jun;461(6):635-43. doi: 10.1007/s00424-011-0936-3. Epub 2011 Mar 1. PubMed PMID: 21360038; PubMed Central PMCID: PMC3108795.1

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