125-29-1|Hydrocodone|(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one|-范德生物科技公司

Hydrocodone

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names：
(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CAS号：
125-29-1
MDL Number：
MF(分子式)： C18H17NO3 MW(分子量)： 295.33
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Hydrocodone
英文别名	Hydrocodone; Dihydrocodeinone; Hydrocodon; Hydrocone; Codinovo; Hydroconum; Knoll Brand of Hydrocodone Tartrate; Nourypharma Brand of Hydrocodone Tartrate; Robidone; Robins Brand of Hydrocodone Tartrate; Wyeth Brand of Hydrocodone Tartrate;
CAS号	125-29-1
SMILES	CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(=O)CC4
Inchi	InChI=1S/C18H15NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-8,17H,9H2,1-2H3/t17-,18-/m0/s1
InchiKey	ZOVHBBRCYGMXTR-ROUUACIJSA-N
分子式 Formula	C18H17NO3
分子量 Molecular Weight	295.33
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Hydrocodone(CAS:125-29-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Hydrocodone is a semi-synthetic opioid synthesized from codeine, one of the opioid alkaloids found in the opium poppy. It is a narcotic analgesic used orally for relief of moderate to severe pain, but also commonly taken in liquid form as an antitussive/cough suppressant. The mechanism of action of hydrocodone is as an Opioid Agonist. Hydrocodone is discontinued (DEA controlled substance).
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Jones CM, Lurie PG, Throckmorton DC. Effect of US Drug EnforcementAdministration's Rescheduling of Hydrocodone Combination Analgesic Products onOpioid Analgesic Prescribing. JAMA Intern Med. 2016 Mar 1;176(3):399-402. doi:10.1001/jamainternmed.2015.7799. PubMed PMID: 26809459.

[2]Slawson D. No Difference Between Oxycodone/Acetaminophen andHydrocodone/Acetaminophen for Acute Extremity Pain. Am Fam Physician. 2016 Mar1;93(5):411. PubMed PMID: 26926980.

[3] Haynes A, Kleinschmidt K, Forrester MB, Young A. Trends in analgesic exposuresreported to Texas Poison Centers following increased regulation of hydrocodone.Clin Toxicol (Phila). 2016 Feb 2

6:1-7. [Epub ahead of print] PubMed PMID:26919555.

[5] Day L, Kleinschmidt K, Forrester MB, Feng SY. Comparison of UnintentionalExposures to Codeine and Hydrocodone Reported to Texas Poison Centers. J EmergMed. 2016 Feb 15. pii: S0736-4679(16)00035-4. doi:10.1016/j.jemermed.2016.01.023. [Epub ahead of print] PubMed PMID: 26899518.

5: Ruan X, Bumgarner GW, Labrie-Brown C, Kaye AD. Feasibility and Utility of theIndividualized Hydrocodone Therapy Based on Phenotype, Pharmacogenetics, andPharmacokinetic Dosing. Clin J Pain. 2016 Feb 17. [Epub ahead of print] PubMedPMID: 26889610.

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