181530-09-6|Zinquin ethyl ester|Zinquin ethyl ester, Zn2+ selective fluorescent probe|MFCD00797629-范德生物科技公司

Zinquin ethyl ester

NMR下载 COA and HPLC MSDS下载
names：
Zinquin ethyl ester, Zn2+ selective fluorescent probe
CAS号：
181530-09-6
MDL Number： MFCD00797629
MF(分子式)： C21H22N2O5S MW(分子量)： 414.48
EINECS: Reaxys Number:
Pubchem ID:3638243 Brand:BIOFOUNT

Zinquin ethyl ester, Zn2+ selective fluorescent probe(181530-09-6)是Zinquin ethyl ester 是 Zinquin 的荧光衍生物。是亲脂、锌敏感、可渗透细胞的喹诺酮类荧光探针，能够穿透细胞膜表面。荧光 :λex 360 nm, λem 480 nm in DMSO。

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HCC353290-1mg	1mg	97%	¥ 3620.00	¥ 3620.00		1-3days	- +	¥ 0.00

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中文别名	Zinquin ethyl ester(181530-09-6);锌喹乙酯;Zn2+选择性荧光探针;锌离子选择性荧光探针
英文别名	Zinquin ethyl ester, Zn2+ selective fluorescent probe(181530-09-6)
CAS号	181530-09-6
SMILES	CCOC(=O)COC1=CC(=C2C(=C1)C=CC(=N2)C)NS(=O)(=O)C3=CC=C(C=C3)C
Inchi	InChI=1S/C21H22N2O5S/c1-4-27-20(24)13-28-17-11-16-8-7-15(3)22-21(16)19(12-17)23-29(25,26)18-9-5-14(2)6-10-18/h5-12,23H,4,13H2,1-3H3
InchiKey	KCASTCXJTDRDFT-UHFFFAOYSA-N
分子式 Formula	C21H22N2O5S
分子量 Molecular Weight	414.48
闪点 FP	No data available
熔点 Melting point	112-114°C
沸点 Boiling point	~578.0° C at 760 mmHg (Predicted)
Polarizability极化度	No data available
密度 Density	~1.3 g/cm3 (Predicted)
蒸汽压 Vapor Pressure	No data available
溶解度Solubility	Chloroform (Slightly), Dichlormethane (Slightly), DMSO (Slightly), Methanol (Sli
性状	solid
储藏条件 Storage conditions	-20°C Freezer

Zinquin ethyl ester 应用：
Zinquin ethyl ester is a lipophilic, zinc-sensitive, cell-permeable fluorescent probe. It can be found in living cells because the ethyl ester is cleaved by cytosolic esterase to give Zinquin that carry a negative charge, preventing its efflux across the plasma membrane.

产品说明	Zinquin ethyl ester, Zn2+ selective fluorescent probe(181530-09-6)是亲脂、锌敏感、可渗透细胞的喹诺酮类荧光探针.荧光 :λex 360 nm, λem 480 nm in DMSO
Introduction	Zinquin Ethyl Ester(CAS:181530-09-6):only use for non-medical purposes in industrial or scientific research, and not for clinical diagnosis and treatment of humans or animals. This product is not medicinal or edible.
Application1
Application2
Application3

警示图
危险性
危险性警示	P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P313获得医疗建议/护理
安全声明	H315 H319 H335
安全防护	P264 P302+P352 P304+P340 P305+P351+P338 P332+P313 P337+P313
备注

1. Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010).

2. Nowakowski, A.B., and Petering, D.H. Reactions of the fluorescent sensor, zinquin, with the zinc-proteome: Adduct formation and ligand substitution. Inorg. Chem. 50(20), 10124-10133 (2011).

3. Helmersson, A., von Arnold, S., and Bozhkov, P.V. The level of free intracellular zinc mediates programmed cell death/cell survival decisions in plant embryos. Plant Physiol. 147(3), 1158-1167

4.Panzer JK et al. Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis. JCI Insight 5:N/A (2020).

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