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5-HT受体拮抗剂

Release Time:2020-04-16
5-HT(5-羟色胺盐酸盐,血清胺盐酸盐)的神经质主要分布于松果体和下丘脑,可调节食欲,调节体温,调节心境,心血管,内分泌和抑郁等生理功能。 5-HT通过激活不同的5-HT受体可以具有不同的药理作用。因此,5-HT受体拮抗剂已成为药物设计的研究热点[1] [2]。作为专业的试剂供应商,Biofount提供了多种5-HT受体拮抗剂以助您进行科学研究!
1.质量稳定,性价比高

2.现货供应,交货及时
CAS 产品名称 货号 包装规格
Granisetron hydrochloride,98%
盐酸格拉司琼,98%
SC0221 10mg
74050-98-9
 
Ketanserin,98.57% YZM002004 50mg
100mg
84057-84-1   Lamotrigine,99.94% YZM001971 500mg
1g
    85650-52-8        Mirtazapine,99.77%    YZM003194 100mg
200mg
     144598-75-4       Paliperidone,98%
帕利哌酮,98%   
SC0166 10mg
     105826-92-4    Tropisetron Hydrochloride,99.64% YZM003230 10mg
50mg
      138982-67-9 Ziprasidone hydrochloride monohydrate,99.83% YZM003231 10mg
50mg


                        Figure1                             Figure2
Figure1: Structure of Lamotrigine (YZM001971)[1]
Figure2: Interactions of Lamotrigine(YZM001971) with the binding pocket (subdomain IB)[1]

CAS 产品名称 货号 包装规格
485-49-4 d-Bicuculline,98%右旋比扣扣灵碱,98% SC0137 100mg
145040-37-5 Candesartan Cilexetil,98% JT21953 250mg
427-51-0 Cyproterone Acetate,98% JZ0033 1g
5g
74381-53-6 Leuprolide Acetate,99.88% YZM003714 5mg
10mg
1508-75-4 Tropicamide,99%
托吡卡胺,99%
SC0173 1g
5g
25g
 References:
[1]
Poureshghi F, Ghandforoushan P, Safarnejad A, et al. Interaction of an antiepileptic drug, lamotrigine with human serum albumin (HSA): Application of spectroscopic techniques and molecular modeling methods[J]. Journal of Photochemistry and Photobiology B: Biology, 2017, 166: 187-192.
[2]Yatham L N, Beaulieu S, Schaffer A, et al. Optimal duration of risperidone or olanzapine adjunctive therapy to mood stabilizer following remission of a manic episode: A CANMAT randomized double-blind trial[J]. Molecular psychiatry, 2016, 21(8): 1050-1056.
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