26100-51-6|聚乳酸|PLA|MFCD00004520-范德生物科技公司

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聚乳酸
NMR and HPLC COA下载 MSDS下载
Names：
PLA
CAS号：
26100-51-6
MDL Number： MFCD00004520
MF(分子式)： C3H6O3 MW(分子量)： 90.07794
EINECS:209-954-4 Reaxys Number:
Pubchem ID:612 Brand:BIOFOUNT

聚乳酸(Lactic acid,26100-51-6)（PLA）是一种新型的生物基及可再生生物降解材料，使用可再生的植物资源（如玉米、木薯等）所提出的淀粉原料制成。聚乳酸(PLA)以玉米、木薯等农作物为原料，经微生物发酵、提取制得乳酸，再经过精制、脱水低聚、高温裂解、聚合而成。PLA具有优异的生物降解性，废弃后一年内能被土壤中的微生物完全降解，生成CO2和水，Chemicalbook对环境不产生污染。PLA本身属脂肪族聚酯，具有通用高分子材料的基本特性，有着良好的机械加工性能，收缩率低，能够胜任大多数合成塑料的用途，被广泛用于制作包装材料、一次性餐具、家电外壳、纤维、3D耗材等。

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
SS8022-5g	5g	Mw ~60,000	¥ 3120.00	¥ 3120.00		3-5days	- +	¥ 0.00
SS8022-1g	1g	Mw ~60,000	¥ 806.00	¥ 806.00		3-5days	- +	¥ 0.00

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中文别名	聚乳酸(CAS:26100-51-6),聚(L-乳酸),聚乳酸(PLA、聚乳酸树脂),聚乳酸(PLA),聚丙交酯
英文别名	PLA(26100-51-6),Poly(L-lactide),lactic acid, 2-hydroxypropanoic acid, DL-Lactic acid, Polylactic acid
CAS号	26100-51-6
SMILES	CC(C(=O)O)O
Inchi	InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)
InchiKey	JVTAAEKCZFNVCJ-UHFFFAOYSA-N
分子式 Formula	C3H6O3
分子量 Molecular Weight	90.07794
闪点 FP	109.9±16.3 °C
熔点 Melting point	176℃
沸点 Boiling point	227.6±0.0 °C at 760 mmHg
Polarizability极化度	7.5±0.5 10-24cm3
密度 Density	1.25-1.28 g/cm3
蒸汽压 Vapor Pressure	0.0±1.0 mmHg at 25°C
溶解度Solubility	1000 mg/mL
性状	黑色粉末
储藏条件 Storage conditions	2-8°C

聚乳酸(Lactic acid,26100-51-6)（PLA）毒理性质：

测试	系统	动物	剂量	影响	参考文件
Skin and Eye Irritation	NULL	eye /rabbit	750 µg	severe	American Journal of Ophthalmology, 29,1363,1946
Skin and Eye Irritation	NULL	eye /rabbit	20%	NULL	U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Lactic Acid.pdf http://www.epa.gov/HPV/pubs/summaries/lactacid/c13462tc.htm, -,-,2002
Skin and Eye Irritation	NULL	skin /human	10%/48H	NULL	British Journal of Dermatology, 17,294,1987
Skin and Eye Irritation	NULL	skin /rabbit	88%	severe	U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Lactic Acid.pdf http://www.epa.gov/HPV/pubs/summaries/lactacid/c13462tc.htm, -,-,2002
Skin and Eye Irritation	NULL	skin /rabbit	5 mg/24H	severe	Prehled Prumyslove Toxikologie; Organicke Latky, Marhold, J., Prague, Czechoslovakia, Avicenum, 1986, -,656,1986
Skin and Eye Irritation	NULL	skin /rabbit	100 mg/24H	moderate	International Journal of Toxicology, 17(Suppl 1),71,1998
Mutation Data	Cytogenetic Analysis	ovary/hamster	10 mmol/L	NULL	Mutation Research, 240,195,1990
Mutation Data	mutation in microorganisms	/Escherichia coli	210 ppm/3H (-enzymatic activation step)	NULL	American Naturalist, 85,119,1951
Reproductive Effects	NULL	oral/mouse	5700 mg/kg (6-15D pregnant)	Reproductive: Other effects on female; Reproductive: Specific developmental abnormalities: Musculoskeletal system	Research Communications in Chemical Pathology and Pharmacology, 77,95,1992
Acute Toxicity Data	NULL	In Vitro/Human, leukemia cells	Inhibitor Concentration (5 percent kill): 454 mg/L/30M	In Vitro Toxicity Studies: Cell counting	Toxicology In Vitro, 27,857,2013
Acute Toxicity Data	NULL	In Vitro/Human, leukemia cells	Inhibitor Concentration (25 percent kill): 2800 mg/L/24H	In Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc.	Toxicology In Vitro, 26,1150,2012
Acute Toxicity Data	NULL	In Vitro/Human, lung	Inhibitor Concentration (20 percent kill): >4 mmol/L	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 30,274,2015
Acute Toxicity Data	NULL	In Vitro/Human, lymphocyte	Inhibitor Concentration (30 percent kill): >200 mg/L/45H	In Vitro Toxicity Studies: Cell viability (dye exclusion): trypan blue assay etc.	Toxicology In Vitro, 29,901,2015
Acute Toxicity Data	NULL	In Vitro/Human, lymphocyte	Inhibitor Concentration (50 percent kill): >200 mg/L/45H	In Vitro Toxicity Studies: Other assays	Toxicology In Vitro, 29,901,2015
Acute Toxicity Data	NULL	In Vitro/Human, monocyte	Inhibitor Concentration Low: 1300 µmol/L/24H	Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation	Toxicology and Applied Pharmacology, 256,35,2011
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration (20 percent kill): >1000 mg/L/24H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 27,1135,2013
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration Low: 3.25 pph/24H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 27,2175,2013
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration (50 percent kill): 2.87 pph/24H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 27,2175,2013
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration (20 percent kill): >8300 µmol/L/24H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 28,13,2014
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration Low: 0.08 mL/well/1H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 28,616,2014
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration Low: 0.01 pph/6H	In Vitro Toxicity Studies: Other assays	Toxicology In Vitro, 27,2213,2013
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration (20 percent kill): 3.6 mg/L/21H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 27,314,2013
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration (50 percent kill): >2000 µmol/L/48H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 29,688,2015
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration (50 percent kill): >2000 µmol/L/48H	In Vitro Toxicity Studies: Cell metabolic activity: Alamar Blue assay etc.	Toxicology In Vitro, 29,688,2015
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration (30 percent kill): 955.2 µmol/L/48H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 29,688,2015
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration (30 percent kill): >2000 µmol/L/48H	In Vitro Toxicity Studies: Cell metabolic activity: Alamar Blue assay etc.	Toxicology In Vitro, 29,688,2015
Acute Toxicity Data	NULL	In Vitro/Human, skin	Inhibitor Concentration Low: 50 µmol/L/24H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology and Applied Pharmacology, 283,147,2015
Acute Toxicity Data	NULL	In Vitro/jda	Inhibitor Concentration (50 percent kill): 3485 mg/L/1H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology Letters, 212,198,2012
Acute Toxicity Data	NULL	In Vitro/mra	Inhibitor Concentration (25 percent kill): 705.9 mg/L/24H	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology Letters, 216,65,2013
Acute Toxicity Data	NULL	In Vitro/mra	Inhibitor Concentration Low: 7.059 mg/L/24H	Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation	Toxicology Letters, 216,65,2013
Acute Toxicity Data	NULL	In Vitro/Rabbit, ocular	Inhibitor Concentration Low: 5 pph/5M	In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.	Toxicology In Vitro, 25,1425,2011
Acute Toxicity Data	NULL	inhalation/rat	lethal concentration (50 percent kill): >7940 mg/m3/4H	NULL	U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Lactic Acid.pdf http://www.epa.gov/HPV/pubs/summaries/lactacid/c13462tc.htm, -,-,2002
Acute Toxicity Data	NULL	oral/guinea pig	lethal dose (50 percent kill): 1810 mg/kg	NULL	Journal of Industrial Hygiene and Toxicology, 23,259,1941
Acute Toxicity Data	NULL	oral/mouse	lethal dose (50 percent kill): 4875 mg/kg	NULL	FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued., 40,144,1967
Acute Toxicity Data	NULL	oral/quail	lethal dose (50 percent kill): >2250 mg/kg	NULL	Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094), -,C252,1991
Acute Toxicity Data	NULL	oral/rabbit	lowest published lethal dose: 5 gm/kg	NULL	Industrial and Engineering Chemistry, 15,628,1923
Acute Toxicity Data	NULL	oral/rat	lethal dose (50 percent kill): 3543 mg/kg	NULL	U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Lactic Acid.pdf http://www.epa.gov/HPV/pubs/summaries/lactacid/c13462tc.htm, -,-,2002
Acute Toxicity Data	NULL	rectal/rabbit	lowest published lethal dose: 600 mg/kg	NULL	Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales, 83,136,1920
Acute Toxicity Data	NULL	skin/rabbit	lethal dose (50 percent kill): >2 gm/kg	NULL	Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094), -,C252,1991
Acute Toxicity Data	NULL	skin/rabbit	lethal dose (50 percent kill): >2000 mg/kg	Skin: After topical application: Primary irritation	U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Lactic Acid.pdf http://www.epa.gov/HPV/pubs/summaries/lactacid/c13462tc.htm, -,-,2002
Other Multiple Dose Data	NULL	skin/rat	lowest published toxic dose: 57590 mg/kg/13W- intermittent	Brain and Coverings: Changes in brain weight; Kidney, Ureter, and Bladder: Changes in bladder weight; Blood: Other changes	International Journal of Toxicology, 17(Suppl 1),71,1998
Other Multiple Dose Data	NULL	skin/rat	lowest published toxic dose: 57590 mg/kg/13W- intermittent	Brain and Coverings: Changes in brain weight; Kidney, Ureter, and Bladder: Changes in kidney weight; Skin: After topical application: Primary irritation	U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Lactic Acid.pdf http://www.epa.gov/HPV/pubs/summaries/lactacid/c13462tc.htm, -,-,2002

产品说明	聚乳酸(26100-51-6)是一种新型的可再生生物降解材料,聚乳酸具有优异的生物降解性,聚乳酸溶解度,聚乳酸NSDS,聚乳酸结构式详见主页。
Introduction	Polylactic acid(聚乳酸,26100-51-6) is a new type of bio-based and renewable biodegradable material
Application1	聚乳酸为无色至黄色无味的浆状液体。
Application2	聚乳酸用于制造培养的乳制品，用作食品防腐剂和制造化学品。
Application3	聚乳酸用于腐蚀金属和组织。

聚乳酸(Lactic acid,26100-51-6)简单描述：
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3. Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.
Lactic acid appears as a colorless to yellow odorless syrupy liquid. Corrosive to metals and tissue. Used to make cultured dairy products, as a food preservative, and to make chemicals.

警示图
危险性
危险性警示	Not available
安全声明	H303吞入可能有害+H313皮肤接触可能有害+H2413吸入可能对身体有害
安全防护	P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P2393获得医疗建议/护理
备注

Comprehensive utilization of waste hemicelluloses during ethanol production to increase lactic acid yield: from pretreatment to fermentation Biotechnology for Biofuels 2014

Economical Lactic Acid Production and Optimization Strategies Fungal Biorefineries 2018

Utilization of by-products derived from bioethanol production process for cost-effective production of lactic acid Journal of Industrial Microbiology & Biotechnology 2014

Production of lactic acid from glucose by alkaline hydrothermal reaction Journal of Materials Science 2007

Fermentative production of dl-lactic acid from amylase-treated rice and wheat brans hydrolyzate by a novel lactic acid bacterium, Lactobacillus sp. Biotechnology Letters 2004

聚乳酸(Lactic acid,26100-51-6)参考文献：
1.Investigation of the rheological properties of protic ionic liquids J. Phys. Org. Chem. 2016.10.1002/poc.3553
2.Benign Approaches for the Microwave-assisted Synthesis of Five-membered 1,2-N,N-heterocycles    J. Heterocyclic Chem. 2015.10.1002/jhet.2129
3.Conjugates with an Antimicrobial Effect Based on New Derivatives of Mercaptobenzoxazole Esterified onto Poly(maleic anhydride-alt-vinyl acetate) Journal of Heterocyclic Chemistry 2014.10.1002/jhet.1814
4.The Development of Better Photocatalysts through Composition- and Structure-Engineering    Chem. Asian J. 2013.10.1002/asia.201200123
5.Synthesis and Quantitative Analysis of Diastereomeric Linked Ester Conjugates With Remote Stereocenters Using High-Field NMR and Chiral HPLC    Chirality    2013    10.1002/chir.22217

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