鞘氨醇

Chemical safety technical specification

Edition：1.0

Prepared according to GB/T16483、GB/T17519

Revision date：10.07.2019

Date of printing：19.02.2020

Date of initial preparation：25.05.2017

WEB：www.bio-fount.com

SDS number：BIOFOUNT-HXH502338

Copyright: BIOFOUNT BEIJING BIO TECH CO.,LTD

Product number：BIOFOUNT-HXH502338

(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol

List of instructions

Part 1

chemicals and enterprise logo

Part 2

risk overview

Part 3

Composition / composition information

Part 4

first aid measures

Part 5

fire fighting measures

Part 6

Leakage Emergency Treatment

Part 7

handling and storage

Part 8

exposure control / personal protection

Part 9

physical and chemical properties

Part 10

stability and reactivity

Part 11

toxicological information

Part 12

ecological hazard information

Part 13

waste disposal

Part 14

Transport Information

Part 15

information on laws and regulations

Part 16

other supplementary information

Part 1: chemicals and enterprise logo

1.1 product identification

Product Name:

(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol

English Name：

(2S,3R,4E)-2-Amino-4-octadecene-1,3-diol

Product No.:

HXH502338

Brand:

BIOFOUNT

(CAS No.)：

123-78-4

1.2 details of suppliers of safety technical specifications

Name of manufacturer or supplier:

BIOFOUNT BEIJING BIO-TECH CO.,LTD

Manufacturing address:

59 Kangtai Avenue Binhai New District Tianjin

300450 TIANJIN CHINA

BIOFOUNT (Tianjin) Biotechnology Co., Ltd

Jiuzhou tonglvgu Health Industrial Park, No. 59, Kangtai Avenue, Binhai New Area, Tianjin

Post code: 300450

Phone number:

1.3 emergency consultation telephone

Emergency contact number:

1.4 recommended and restricted uses of the substance or mixture

Identified uses:

It is only used for scientific research and development, not for medicine, family or other purposes.

Part 2: risk overview

2.1 hazard categories of GHS

No data available

2.2 GHS labeling elements, including precautionary statements

Pictogram

No data available

Signal word

No data available

Declaration of danger

No data available

Warning statement

No data available

preventive measure

No data available

Accident response

1. In case of accident or emergency during the use of chemicals, the party concerned shall report to the person in charge of the emergency response team as soon as possible, and the emergency response team shall take measures to prevent the situation from expanding. 3. The emergency team shall take rescue measures for the victims.

Storage

No data available

Waste disposal

No data available

2.3 physical and chemical hazards

No data available

2.4 health hazards

No data available

2.5 environmental hazards

No data available

2.6 other hazards

No data available

Part 3: Composition / composition information

Substance / mixture

material 

3.1 substances

Molecular formula

C18H37NO2

molecular weight

299.5

（CAS No.）

123-78-4

EC- number

No data available

According to the corresponding regulations, there is no need to disclose specific components.

Part 4: first aid measures

4.1 description of necessary first aid measures inhalation

inhalation

Inhalation: Immediately leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

Skin contact

Skin:Immediately flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, Immediately call a physician and be prepared to transport the victim to a hospital for treatment.

Eye contact

eyes: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. Immediately transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Ingestion

Ingestion: Do not induce vomiting,If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and Immediately call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT Induce vomiting.Immediately transport the victim to a hospital.

4.2 most important symptoms and health effects

The most important known symptoms and effects are described in the label (see Chapter 2.2) and / or Chapter 11

4.3 instructions and instructions for timely medical treatment and special treatment required

No data available

4.4 special tips for doctors

No data available

Part 5: fire fighting measures

5.1 extinguishing media

Fire extinguishing method and agent

Fires involving this compound should be controlled using a dry chemical, carbon dioxide, foam or Halon extinguisher.

5.2 special hazards from this substance or mixture

No data available

5.3 precautions and protection measures for fire fighting

In case of small-scale fire, masks shall be worn to prevent the inhalation of toxic gas. In case of fire, the emergency response system shall be started in time to evacuate to the upper air outlet, and the local fire department shall be contacted to put out the fire.

Part 6: Leakage Emergency Treatment

6.1 personnel protection measures, protective equipment and emergency disposal procedures

1. Start the emergency response system first after leakage. 2. Before leakage treatment, wear safety protection shoes, safety protection gloves (anti acid and alkali gloves are required for strong acid substances), and wear corresponding protective masks according to the inhalation risk.

For personal protection, see Part 8.

6.2 environmental protection measures

Refer to the treatment method of Fande biochemical waste to prevent harm to the environment. After treatment, the waste shall be treated by a qualified waste treatment structure to avoid environmental pollution. 

6.3 storage, removal methods and disposal materials of leaked chemicals

The leaked chemicals shall be treated according to the treatment method of Fande biological chemical waste. Before treatment, the leaking area shall be enclosed with chemical absorbent rock wool to form a "cofferdam" to prevent the leakage from expanding.

6.4 reference to other parts

See section 13 for disposal.

Part 7: handling and storage

7.1 precautions for safe operation

Please wear masks, gloves and other protective articles during use to avoid contact with skin, inhalation and accidental ingestion.

See Section 2.2 for precautions.

7.2 conditions for safe storage, including any incompatibility

It is unable to provide detailed data for the time being. Try to avoid mixed storage with other compounds and storage in dark and ventilated places.

Part 8: exposure control / personal protection

8.1 control parameters

Hazard composition and occupational exposure limit

No data available

8.2 exposure control

Appropriate technical controls

No data available

Personal protective equipment

Eye protection

Please use equipment tested and approved by official standards such as NIOSH (USA) or en 166 (EU) for eye protection.

Skin protection

Take out by hand: gloves must be inspected before use. Please use proper methods to remove the gloves (do not touch the outer surface of the gloves), and avoid any skin parts contacting the product. After use, please handle the contaminated gloves carefully according to relevant laws and regulations and effective laboratory rules and procedures. Please wash and dry your hands.

The selected protective gloves must meet the specifications given in regulation (EU) 2016 / 425 and the en 374 standard derived from it.

Full contact

Material: NBR

Minimum layer thickness 0.11 mm

Solvent penetration time: 480 minutes

Splash protection

Material: NBR

Minimum layer thickness 0.11 mm

Solvent penetration time: 480 minutes

If applied in solvent form or mixed with other substances, or under conditions different from those specified in en 374, please contact the supplier of gloves approved by EC. This recommendation is only suggestive and must be evaluated and confirmed by an industrial hygiene expert familiar with the specific situation our customer plans to use. This should not be interpreted as providing approval for any particular usage method.

Body protection

Choose physical protection measures according to the type, concentration and quantity of hazardous substances and specific workplace. The type of protective equipment must be selected according to the concentration and quantity of hazardous substances in the specific workplace.

respiratory system protection

There is no need to protect breathing. To protect against dust damage, use N95 (US) or P1 (EN 143) dust masks. Respirators use respirators and parts that have been tested and passed government standards such as NIOSH (US) or cen (EU).

Control of environmental exposure

Do not let the product into the sewer.

Part 9: physical and chemical properties

9.1 information on basic physical and chemical properties

Appearance and character

shape：No data available

colour：No data available

smell

No data available

Odor threshold

No data available

PH value

No data available

Melting point / freezing point

No data available

Initial boiling point and boiling range

445.9±45.0 °C at 760 mmHg

flash point

223.5±28.7 °C

Evaporation rate

No data available

Flammability (solid, gas)

No data available

High / low flammability or explosive limits

No data available

Vapor pressure

0.0±2.4 mmHg at 25°C

Vapor density

No data available

Density / relative density

0.9±0.1 g/cm3

Water solubility

.; chloroform:; 20 mg/mL, clear, colorless to very faintly yellowIndofine[71-1086]Chloroform:20 mg ml,clear,colorless to very faintly yellowIndofine[56-1086] , [56-1302]Soluble to 5 mM in DMSO and to 50 mM in ethanolTocris Bioscience0633,633

Partition coefficient of n-octanol / water

Log POW:6.40

Air distribution coefficient of n-octanol

Log Kow used: 5.53 (KowWin est) Log Kaw used: -7.347 (HenryWin est) Log Koa (KOAWIN v1.10 estimate): 12.877 Log Koa (experimental database): None/

Spontaneous combustion temperature

No data available

decomposition temperature

No data available

viscosity

No data available

Explosion characteristics

No data available 

Oxidizing

No data available

Estimation of hydrosol from fragments

WatSol(v1.01est)=63.817mg/L 

Henry's law constant (25 ℃)

Bond Method : 1.10E-009 atm-m3/mole Group Method: Incomplete Henrys LC [VP/WSol estimate using EPI values]: 1.846E-009 atm-m3/mole/ 

9.2 other safety information

No data available

Part 10: stability and reactivity

10.1 stability

No data available

10.2 hazardous reactions

No data available

10.3 conditions to avoid

No data available 

10.4 prohibited substances

Strong oxidant 

10.5 hazardous decomposition products

No data available 

Part 11: toxicological information

11.1 toxicological impact information

toxicity

No data available

Skin corrosion / irritation

No data available 

Serious eye injury / eye irritation

No data available

Respiratory or skin allergies

No data available

Germ cell mutagenicity

No data available 

carcinogenicity

No data available 

Reproductive toxicity

No data available 

Specific target organ systemic toxicity (one exposure)

No data available 

Specific target organ systemic toxicity (repeated exposure)

No data available 

Inhalation hazard

No data available 

Additional description

No data available 

Part 12: ecological hazard information

12.1 ecotoxicity

No data available 

12.2 durability and degradability

No data available 

12.3 possibility of rapid biodegradation

Biowin1 (Linear Model) : 1.1847 Biowin2 (Non-Linear Model) : 0.9810 

12.4 expert investigation of biodegradation results

Biowin3 (Ultimate Survey Model): 3.1800 (weeks ) Biowin4 (Primary Survey Model) : 3.9869 (days ) 

12.5 possibility of MITI biodegradation

Biowin5 (MITI Linear Model) : 0.7305 Biowin6 (MITI Non-Linear Model): 0.7434 

12.6 possibility of anaerobic biodegradation

Biowin7 (Anaerobic Linear Model): 0.7407 

12.7 ready made biodegradability prediction

YES 

12.8 hydrocarbon biodegradation

Structure incompatible with current estimation method!/ 

12.9 adsorption of aerosols

Vapor pressure (liquid/subcooled): 3.69E-006 Pa (2.77E-008 mm Hg) Log Koa (Koawin est ): 12.877 Kp (particle/gas partition coef. (m3/ug)): Mackay model : 0.812 Octanol/air (Koa) model: 1.85 Fraction sorbed to airborne particulates (phi): Junge-Pankow model : 0.967 Mackay model : 0.985 Octanol/air (Koa) model: 0.993 / 

12.10 hydroxyl radical reaction

OVERALL OH Rate Constant = 133.9437 E-12 cm3/molecule-sec [Cis-isomer] OVERALL OH Rate Constant = 141.5437 E-12 cm3/molecule-sec [Trans-isomer] Half-Life = 0.958 Hrs (12-hr day; 1.5E6 OH/cm3) [Cis-isomer] Half-Life = 0.907 Hrs (12-hr day; 1.5E6 OH/cm3) [Trans-isomer] 

12.11 ozone reaction

OVERALL Ozone Rate Constant = 13.000000 E-17 cm3/molecule-sec [Cis-] OVERALL Ozone Rate Constant = 20.000000 E-17 cm3/molecule-sec [Trans-] Half-Life = 2.116 Hrs (at 7E11 mol/cm3) [Cis-isomer] Half-Life = 1.375 Hrs (at 7E11 mol/cm3) [Trans-isomer] Reaction With Nitrate Radicals May Be Important! 

12.12 fraction of particulate adsorption in air (PHI)

0.976 (Junge,Mackay) Note: the sorbed fraction may be resistant to atmospheric oxidation/ 

12.13 soil adsorption coefficient

Koc : 783.6 Log Koc: 2.894 / 

12.14 alkali / acid catalyzed hydrolysis (25 ℃)

Rate constants can NOT be estimated for this structure!/ 

12.15 estimating bioaccumulation using log Kow

Log BCF from regression-based method = 2.557 (BCF = 360.7) log Kow used: 5.53 (estimated)/ 

12.16 removal in wastewater treatment

Total removal: 88.65 percent Total biodegradation: 0.75 percent Total sludge adsorption: 87.90 percent Total to Air: 0.00 percent (using 10000 hr Bio P,A,S)/ 

12.17 three level fugacity model

Mass Amount Half-Life Emissions (percent) (hr) (kg/hr) Air 0.0347 1.01 1000 Water 10.7 360 1000 Soil 53.2 720 1000 Sediment 36 3.24e+003 0 Persistence Time: 867 hr// 

12.18 mobility in soil

No data available 

12.19 evaluation of PBT and vpvb results

No data available 

12.20 other harmful effects on the environment

No data available 

Part 13: waste disposal

13.1 waste treatment

Product method

None 

Contaminated packaging

None 

Part 14: Transport Information

14.1 UN number

ADR/RID：

None 

IMDG：

None 

IATA-DGR：

None 

14.2 UN proper shipping name

ADR/RID：

None 

IMDG：

None 

IATA-DGR：

None 

14.3 Transport hazard class(es)

ADR/RID：

None 

IMDG：

None 

IATA-DGR：

None 

14.4 Packaging group

ADR/RID ：

None 

IM0DG：

None 

IATA-DGR：

None 

14.5 Environmental hazards

None 

14.6 Special precautions for user

None 

14.7 Incompatible materials

None 

Part 15: information on laws and regulations

15.1 rules / regulations specific to the safety, health and environment of the substance or mixture

Applicable laws and regulations

None 

Other provisions

None 

Part 16: other supplementary information

Other information

Copyright:FOUNT BEIJING BIO TECH CO.,LTD. Unlimited paper copies are permitted, for internal use only.

The above information is deemed to be correct, but does not contain all information. It is only used as a guide. The information in this document is based on what we know at present and is applicable to this product in terms of correct safety tips. This information does not guarantee the nature of this product. Biofount and its affiliates shall not be liable for any damage caused by any operation or contact with the above products. For further terms of use, see the reverse side of the invoice or packing slip. For further terms and conditions of sale, please refer to http://www.bio-foundation.com/ or the back of the invoice or packing list.

The logo on the header or footer of this document may temporarily not visually match the product purchased as we are transitioning our brand. However, all information about the products in this article remains unchanged and is consistent with the products ordered. For more information, please contact: sales@bio-foundation.com