148477-71-8|螺螨酯|Spirodiclofen|-范德生物科技公司

螺螨酯

NMR下载 COA and HPLC MSDS下载
names：
Spirodiclofen
CAS号：
148477-71-8
MDL Number：
MF(分子式)： C21H24Cl2O4 MW(分子量)： 411.319
EINECS:604-636-5 Reaxys Number:
Pubchem ID:177863 Brand:BIOFOUNT

螺螨酯(148477-71-8,Spirodiclofen)是一种有机氯杀螨剂，一种二氯苯，一种氧杂螺化合物和一种γ-内酯。螺螨酯衍生自1,3-二氯苯。螺螨酯，一种四氢代酸衍生物，是一种广谱杀螨剂。

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
HCC345138-250mg	250mg	97%	¥ 1596.00	¥ 1596.00		4-7周	- +	¥ 0.00

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询价

中文别名	螺螨酯(148477-71-8,Spirodiclofen)
英文别名	Spirodiclofen(148477-71-8)
CAS号	148477-71-8
Inchi	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3
InchiKey	OYNVHVAEOLJJPV-UHFFFAOYSA-N
分子式 Formula	C21H24Cl2O4
分子量 Molecular Weight	411.319
溶解度Solubility	Chloroform (Slightly), DMSO, Methanol (Sparingly)
性状	白色至灰白色固体粉末
储藏条件 Storage conditions	存放在阴凉干燥处，短期（数天至数周）在0-4℃，长期（数月至数年）在-20℃。

螺螨酯(148477-71-8,Spirodiclofen)对人类毒性的摘要：
This study evaluated the effects of spirodiclofen, BAJ 2510, and one of the hydroxy BAJ 2510 metabolites, primarily on hormone response elements in human cell lines (MCF 7 breast cancer cell line or prostate PC-3 cell line for estrogen and androgen receptor, respectively). Hormone response was quantified via luciferase reporter genes using a chemiluminescence reader. In some cases, binding studies for alpha and beta estrogen receptors followed, using a fluorescence polarization technique which could be performed in microtiter wells. At pH's of 6 to 6.5, BAJ 2510 displayed estrogenic and anti-estrogenic activities. BAJ 2510 bound to alpha and beta estrogen receptors in this pH range. BAJ 2510 had no effects in the reporter or receptor binding assays at physiological pH (7 or higher). Spirodiclofen and hydroxy BAJ 2510 were uniformly negative in all assays.

螺螨酯(148477-71-8,Spirodiclofen) 实验注意事项：
1.实验前需戴好防护眼镜，穿戴防护服和口罩，佩戴手套，避免与皮肤接触。
2.实验过程中如遇到有毒或者刺激性物质及有害物质产生，必要时实验操作需要手套箱内完成以免对实验人员造成伤害
3.实验后产生的废弃物需分类存储，并交于专业生物废气物处理公司处理，以免造成环境污染

Spirodiclofen(148477-71-8) Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

Tag:螺螨酯(148477-71-8,Spirodiclofen),螺螨酯试剂,螺螨酯的纯度,螺螨酯的作用,螺螨酯的合成,螺螨酯的外观,螺螨酯的用途,螺螨酯的生产,螺螨酯的厂家,螺螨酯的MSDS,螺螨酯的价格,螺螨酯的注意事项,螺螨酯的溶解度,螺螨酯的性质

产品说明	螺螨酯(148477-71-8,Spirodiclofen)可以作为药物杂质对照品以及生物医药类试剂。
Introduction	Spirodiclofen(148477-71-8,螺螨酯) can be used as a reference substance for drug impurities and reagents，only for research.
Application1
Application2
Application3

警示图
危险性	warning
危险性警示	Not available
安全声明	H303+H313+H333
安全防护	P264+P280+P305+P351+P338+P337+P313
备注	实验过程中防止吸入、食入，做好安全防护

象形图
信号警告	Danger
GHS危险说明	H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H350: May cause cancer [Danger Carcinogenicity] H361f: Suspected of damaging fertility [Warning Reproductive toxicity] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
防范说明代码	P201, P202, P260, P261, P272, P273, P280, P281, P302+P352, P308+P313, P314, P321, P333+P313, P363, P391, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.)

Dissipation, residues, and risk assessment of spirodiclofen in citrus(Environmental Monitoring and Assessment,2013)

Effects of spirodiclofen on reproduction in a susceptible and resistant strain of Tetranychus urticae (Acari: Tetranychidae)(Experimental and Applied Acarology,2008)

Sublethal effects of spirodiclofen on life history and life-table parameters of two-spotted spider mite (Tetranychus urticae)( Experimental and Applied Acarology,2007)

Untersuchungen zur Akarizidresistenz an Populationen der Obstbaumspinnmilbe, Panonychus ulmi KOCH (Acari: Tetranychidae) aus dem Bodenseegebiet(Gesunde Pflanzen,2006)

Sublethal effects of spirodiclofen, abamectin and pyridaben on life-history traits and life-table parameters of two-spotted spider mite, Tetranychus urticae (Acari: Tetranychidae)

1.Comparative toxicity of an acetogenin-based extract and commercial pesticides against citrus red mite.
Ribeiro Ldo P1, Zanardi OZ, Vendramim JD, Yamamoto PT. Exp Appl Acarol. 2014;64(1):87-98. doi: 10.1007/s10493-014-9810-2. Epub 2014 Apr 3.
Acetogenins, a class of natural compounds produced by some Annonaceae species, are potent inhibitors of mitochondrial electron transport systems. Although the cellular respiration processes are an important biochemical site for the acaricidal action of compounds, few studies have been performed to assess the bioactivity of acetogenin-based biopesticides on spider mites, mainly against species that occur in orchards. Using residual contact bioassays, this study aimed to evaluate the bioactivity of an ethanolic extract from Annona mucosa seeds (ESAM) (Annonaceae) against the citrus red mite Panonychus citri (McGregor) (Acari: Tetranychidae), an important pest of the Brazilian citriculture. ESAM is a homemade biopesticide which was previously characterized by its high concentration of acetogenins. It caused both high mortality of P. citri females (LC50 = 7,295, 4,662, 3,463, and

2,608 mg l(-1), after 48, 72, 96, and 120 h of exposure, respectively) and significant oviposition deterrence (EC50 = 3.
2.Lethal and Sublethal Impacts of Acaricides on Tamarixia radiata (Hemiptera: Eulophidae), an Important Ectoparasitoid of Diaphorina citri (Hemiptera: Liviidae).
Lira AC1, Zanardi OZ2, Beloti VH2, Bordini GP2, Yamamoto PT3, Parra JR2, Carvalho GA1. J Econ Entomol. 2015 Oct;108(5):2278-88. doi: 10.1093/jee/tov189. Epub 2015 Jul 3.
The use of synthetic acaricides for management of pest mites may alter the efficacy of the ectoparasitoid Tamarixia radiata (Waterston) in biological control of Diaphorina citri Kuwayama, the vector of the bacteria associated with huanglongbing (HLB) in citrus orchards. We evaluated the toxicity of 16 acaricides that are recommended for the control of citrus-pest mites to T. radiata. Acrinathrin, bifenthrin, carbosulfan, and fenpropathrin caused high acute toxicity and were considered harmful (mortality >77%) to T. radiata. Abamectin, diflubenzuron, etoxazole, fenbutatin oxide, fenpyroximate, flufenoxuron, hexythiazox, propargite, spirodiclofen, and sulfur caused low acute toxicity and affected the parasitism rate and emergence rate of adults (F1 generation), and were considered slightly harmful to T. radiata. Dicofol and pyridaben did not affect the survival and action of the ectoparasitoid, and were considered harmless. In addition to its acute toxicity, carbosulfan caused mortality higher than 25% for >30 d after application, and was considered persistent.

3.TESTING SIDE-EFFECTS OF COMMON PESTICIDES ON A. SWIRSKII UNDER GREENHOUSE CIRCUMSTANCES.
Audenaert J, Vissers M, Gobin B. Commun Agric Appl Biol Sci. 2014;79(2):207-10.
If a grower uses predatory mites, and should use chemical compounds, he needs to be very careful in his choice of products. The selected products have to be efficient against the target pest and at the same time compatible with the present beneficial's. Useful tools for such product selection under greenhouse circumstances are side effects lists. These lists are freely available on the websites of producing companies of biological control agents. But not all products (e.g. newly developed ones) have been tested for side effects. Moreover the information already available in these tables is not based on field tests. For this reason, we have developed a protocol for quick screening of side effects of chemical plant protection products under field conditions. For these experiments we have chosen the predatory mite Amblyseius swirskii as test organism, because this is an often used phytoseiid mite, which is very sensitive to pesticides. Hibiscus rosa sinensis is the standard reference plant in our side effects trials because the chosen predatory mite has shown very good control of pests on this plant species.

4.Dispersive liquid-liquid microextraction for the determination of new generation pesticides in soils by liquid chromatography and tandem mass spectrometry.
Pastor-Belda M1, Garrido I2, Campillo N1, Viñas P1, Hellín P2, Flores P2, Fenoll J3. J Chromatogr A. 2015 May 15;1394:1-8. doi: 10.1016/j.chroma.2015.03.032. Epub 2015 Mar 23.
A sensitive method for the determination of five new generation pesticides (chlorantraniliprole, spirotetramat, spiromesifen, spirodiclofen and flubendiamide) in soil samples has been developed using liquid chromatography and tandem mass spectrometry (LC-MS(2)) with a triple-quadrupole in the multiple reaction monitoring mode. The target analytes are released from the solid matrix by single-phase extraction in acetonitrile (SLE), this organic phase being used as dispersant solvent in the dispersive liquid-liquid microextraction (DLLME) step. The different parameters affecting the extraction efficiency in DLLME were carefully studied, being 1.5mL of acetonitrile extract (disperser solvent), 125μL carbon tetrachloride (extraction solvent) and 10mL aqueous solution, the selected conditions. The enriched organic phase was evaporated, reconstituted with 50μL acetonitrile and injected into a liquid chromatograph with a mobile phase composed of acetonitrile.

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