142978-18-5|CCVJ荧光探针|CCVJ|MFCD00274408-范德生物科技公司

CCVJ荧光探针

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names：
CCVJ
CAS号：
142978-18-5
MDL Number： MFCD00274408
MF(分子式)： C16H16N2O2 MW(分子量)： 268.3
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

CCVJ（142978-18-5）是一种荧光分子转子，其特点是具有低背景荧光、低荧光各向异性以及具有良好的水溶性。此外，CCVJ 具有大的疏水结构，使其能够以非共价方式与溶液中蛋白质中的疏水袋状物结合，CCVJ 是用于与蛋白质结合的荧光探针。

货品编码	规格	纯度	价格 (¥)	现价(¥)	库存描述	数量	总计 (¥)
HCQ000695-20mg	20mg	98%	¥ 4500.00	¥ 4500.00	Instock1-2days	- +	¥ 0.00
HCQ000695-5mg	5mg	98%	¥ 1780.00	¥ 1780.00	Instock1-2days	- +	¥ 0.00
HCQ000695-1mg	1mg	98%	¥ 980.00	¥ 980.00	Instock1-2days	- +	¥ 0.00

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询价

中文别名	CCVJ；142978-18-5；9-(2-Carboxy-2-cyanovinyl)julolidine
英文别名	CCVJ；2-cyano-3-(2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizin-9-yl)-2-propenoic acid；9-(2-Carboxy-2-cyanovinyl)julolidine?
CAS号	142978-18-5
SMILES	OC(/C(C#N)=C/C1=CC(CCC2)=C(N2CCC3)C3=C1)=O
Inchi	InChI=1S/C16H16N2O2/c17-10-14(16(19)20)9-11-7-12-3-1-5-18-6-2-4-13(8-11)15(12)18/h7-9H,1-6H2,(H,19,20)/b14-9+
InchiKey	JXENNHTVELFRHV-NTEUORMPSA-N
分子式 Formula	C16H16N2O2
分子量 Molecular Weight	268.3
闪点 FP	280.0±30.1 °C
熔点 Melting point	no data available
沸点 Boiling point	539.5±50.0 °C at 760 mmHg
Polarizability极化度	29.4±0.5 10-24cm3
密度 Density	1.3±0.1 g/cm3
蒸汽压 Vapor Pressure	0.0±1.5 mmHg at 25°C
溶解度Solubility
性状	Solid，power
储藏条件 Storage conditions	储存条件：-20° C，避光防潮密闭干燥。运输条件：2-8℃运输

CCVJ（142978-18-5）应用说明：

Fluorescent molecular rotors are molecules whose fluorescence is inversely proportional to its intramolecular rotation.1 The intramolecular rotation of these probes, and hence their fluorescence, depends on the immediate microenvironment of the probe.As a result, fluorescent molecular rotors are used to evaluate changes in solution and membrane viscosity, polymerization or aggregation processes, and protein (un)folding. CCVJ is a fluorescent molecular rotor characterized by low background fluorescence, low fluorescence anisotropy, and good water solubility.Moreover, CCVJ has large hydrophobic structures, allowing it to associate in a non-covalent manner with hydrophobic pockets in proteins in solution.CCVJ is broadly used to monitor changes in solution and molecular characteristics.

产品说明	CCVJ（142978-18-5）是一种荧光分子转子，其特点是具有低背景荧光、低荧光各向异性和良好的水溶性。CCVJ 是用于与蛋白质结合的荧光探针。
Introduction	CCVJ has large hydrophobic structures, allowing it to associate in a non-covalent manner with hydrophobic pockets in proteins in solution.1 CCVJ is broadly used to monitor changes in solution and mole
Application1
Application2
Application3

警示图
危险性
危险性警示
安全声明	H301+H311+H315+H319+H331
安全防护	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
备注

1. Haidekker, M.A., Nipper, M., Mustafic, A., et al. Dyes with segmental mobility: Molecular rotors. Advanced Fluorescence Reporters in Chemistry and Biology I: Fundamentals and Molecular Design 267-3

2. Haidekker, M.A., Ling, T., Angolo, M., et al. New fluorescent probes for the measurement of cell membrane viscosity. Chemistry & Biology 8(2), 123-131 (2001).

3. Levitt, J.A., Chung, P.H., Kuimova, M.K., et al. Fluorescence anisotropy of molecular rotors. Chemphyschem. 12, 662-672 (2011).

4. Iio, T., Itakura, M., Takahashi, S., et al. 9-(Dicyanovinyl)julolidine binding to bovine brain calmodulin. Journal of Biochemistry 109(4), 499-502 (1991).

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