125774-71-2|WS 9326A|WS 9326A|-范德生物科技公司

WS 9326A

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names：
WS 9326A
CAS号：
125774-71-2
MDL Number：
MF(分子式)： C54H68N8O13 MW(分子量)： 1037.18
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
FMK21011-100mg	100mg	>98%	¥ 0.00	¥ 0.00		Get quote	- +	¥ 0.00

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中文别名	(E)-N-((3S,6R,9R,12R,15R,21S,22R)-6-(2-amino-2-oxoethyl)-12-benzyl-18-((Z)-4-hydroxybenzylidene)-9-((R)-1-hydroxyethyl)-3-(hydroxymethyl)-15-isobutyl-19,22-dimethyl-2,5,8,11,14,17,20-heptaoxo-1-oxa-4,7,10,13,16,19-hexaazacyclodocosan-21-yl)-3-(2-((E)-pent-1-en-1-yl)phenyl)acrylamide
英文别名	WS 9326A; WS-326A; WS9326A;
CAS号	125774-71-2
Inchi	InChI=1S/C54H68N8O13/c1-7-8-10-17-36-18-13-14-19-37(36)22-25-45(67)60-47-33(5)75-54(74)42(30-63)59-49(69)41(29-44(55)66)58-52(72)46(32(4)64)61-50(70)40(27-34-15-11-9-12-16-34)56-48(68)39(26-31(2)3)57-51(71)43(62(6)53(47)73)28-35-20-23-38(65)24-21-35/h9-25,28,31-33,39-42,46-47,63-65H,7-8,26-27,29-30H2,1-6H3,(H2,55,66)(H,56,68)(H,57,71)(H,58,72)(H,59,69)(H,60,67)(H,61,70)/b17-10+,25-22+,43-28-/t32-,33-,39-,40-,41-,42+,46-,47+/m1/s1
InchiKey	BVVWVQZZLUNSNV-PNRTYFKVSA-N
分子式 Formula	C54H68N8O13
分子量 Molecular Weight	1037.18
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	WS 9326A(CAS:125774-71-2):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	WS 9326A is a tachykinin receptor antagonist isolaed from Streptomyces violaceusniger.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Desouky SE, Shojima A, Singh RP, Matsufuji T, Igarashi Y, Suzuki T, Yamagaki T, Okubo K, Ohtani K, Sonomoto K, Nakayama J. Cyclodepsipeptides produced by actinomycetes inhibit cyclic-peptide-mediated quorum sensing in Gram-positive bacteria. FEMS Microbiol Lett. 2015 Jul;362(14). pii: fnv109. doi: 10.1093/femsle/fnv109. Epub 2015 Jul 5. PubMed PMID: 26149266.

[2]Yu Z, Vodanovic-Jankovic S, Kron M, Shen B. New WS9326A congeners from Streptomyces sp. 9078 inhibiting Brugia malayi asparaginyl-tRNA synthetase. Org Lett. 2012 Sep 21;14(18):4946-9. Epub 2012 Sep 12. PubMed PMID: 22967068; PubMed Central PMCID: PMC3460372.

[3] Hayashi K, Hashimoto M, Shigematsu N, Nishikawa M, Ezaki M, Yamashita M, Kiyoto S, Okuhara M, Kohsaka M, Imanaka H. WS9326A, a novel tachykinin antagonist isolated from Streptomyces violaceusniger no. 9326. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1992 Jul;45(7):1055-63. PubMed PMID: 1381343.

[4] Shigematsu N, Kayakiri N, Okada S, Tanaka H. Total synthesis of WS9326A, a potent tachykinin antagonist from Streptomyces violaceoniger. Chem Pharm Bull (Tokyo). 1997 Feb;45(2):236-42. PubMed PMID: 9118439.

[5] Hashimoto M, Hayashi K, Murai M, Fujii T, Nishikawa M, Kiyoto S, Okuhara M, Kohsaka M, Imanaka H. WS9326A, a novel tachykinin antagonist isolated from Streptomyces violaceusniger no. 9326. II. Biological and pharmacological properties of WS9326A and tetrahydro-WS9326A (FK224). J Antibiot (Tokyo). 1992 Jul;45(7):1064-70. Erratum in: J Antibiot (Tokyo) 1992 Dec;45(12):C-9. PubMed PMID: 1381344.

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