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Resact_91316-25-5_产品详情
91316-25-5
  • names:

    Resact

  • CAS号:

    91316-25-5

    MDL Number:
  • MF(分子式): C50H86N18O15S2 MW(分子量): 1243.46
  • EINECS: Reaxys Number:
  • Pubchem ID: Brand:BIOFOUNT
Resact
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中文别名 (6R,11R,14S,17S,23S,28aS)-11-amino-N-((3S,15S,18S)-18-carbamoyl-15-(3-guanidinopropyl)-2,20-dimethyl-4,7,10,13,16-pentaoxo-5,8,11,14,17-pentaazahenicosan-3-yl)-17-((R)-1-hydroxyethyl)-14-isopropyl-23-methyl-1,4,12,15,18,21,24-heptaoxotetracosahydro-1H,10H-pyrrolo[2,1-j][1,2]dithia[5,8,11,14,17,20,23]heptaazacyclohexacosine-6-carboxamide
英文别名 Resact;
CAS号 91316-25-5
Inchi InChI=1S/C50H86N18O15S2/c1-23(2)15-30(41(52)75)64-43(77)29(11-9-13-55-50(53)54)62-36(73)18-57-33(70)16-56-34(71)17-59-46(80)38(24(3)4)66-44(78)31-22-85-84-21-28(51)42(76)65-39(25(5)6)48(82)67-40(27(8)69)47(81)60-19-35(72)61-26(7)49(83)68-14-10-12-32(68)45(79)58-20-37(74)63-31/h23-32,38-40,69H,9-22,51H2,1-8H3,(H2,52,75)(H,56,71)(H,57,70)(H,58,79)(H,59,80)(H,60,81)(H,61,72)(H,62,73)(H,63,74)(H,64,77)(H,65,76)(H,66,78)(H,67,82)(H4,53,54,55)/t26-,27+,28-,29-,30-,31-,32-,38-,39-,40-/m0/s1
InchiKey AIUYQNQCTFEINK-WSZFUOGHSA-N
分子式 Formula C50H86N18O15S2
分子量 Molecular Weight 1243.46
溶解度Solubility
性状 Solid powder
储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).
产品说明 Resact(CAS:91316-25-5):仅限应用于工业或者科学研究过程中非医疗目的,不应用于人类或动物的临床诊断以及治过程疗,该产品非药用,非食用。
IntroductionResact is an extracellular peptide from egg jelly of sea urchin Arbacia punctulata with pH 6.6.
Application1
Application2
Application3
警示图
危险性 Warning
危险性警示
安全声明
安全防护
备注
[1]Ward GE, Brokaw CJ, Garbers DL, Vacquier VD. Chemotaxis of Arbacia punctulata spermatozoa to resact, a peptide from the egg jelly layer. J Cell Biol. 1985 Dec;101(6):2324-9. PubMed PMID: 3840805; PubMed Central PMCID: PMC2113998.
[2]Suzuki N, Garbers DL. Stimulation of sperm respiration rates by speract and resact at alkaline extracellular pH. Biol Reprod. 1984 Jun;30(5):1167-74. PubMed PMID: 6547354.
[3] Shimomura H, Garbers DL. Differential effects of resact analogues on sperm respiration rates and cyclic nucleotide concentrations. Biochemistry. 1986 Jun 3;25(11):3405-10. PubMed PMID: 3015204.
[4] Bentley JK, Shimomura H, Garbers DL. Retention of a functional resact receptor in isolated sperm plasma membranes. Cell. 1986 Apr 25;45(2):281-8. PubMed PMID: 2870813.
[5] Shimomura H, Dangott LJ, Garbers DL. Covalent coupling of a resact analogue to guanylate cyclase. J Biol Chem. 1986 Nov 25;261(33):15778-82. PubMed PMID: 2877982.
6: Inamdar MV, Kim T, Chung YK, Was AM, Xiang X, Wang CW, Takayama S, Lastoskie CM, Thomas FI, Sastry AM. Assessment of sperm chemokinesis with exposure to jelly coats of sea urchin eggs and resact: a microfluidic experiment and numerical study. J Exp Biol. 2007 Nov;210(Pt 21):3805-20. PubMed PMID: 17951422.7: Solzin J, Helbig A, Van Q, Brown JE, Hildebrand E, Weyand I, Kaupp UB. Revisiting the role of H+ in chemotactic signaling of sperm. J Gen Physiol. 2004 Aug;124(2):115-24. PubMed PMID: 15277573; PubMed Central PMCID: PMC2229618.8: Garbers DL, Bentley JK, Dangott LJ, Ramarao CS, Shimomura H, Suzuki N, Thorpe D. Peptides associated with eggs: mechanisms of interaction with spermatozoa. Adv Exp Med Biol. 1986;207:315-57. Review. PubMed PMID: 2881430.9: Suzuki N, Shimomura H, Radany EW, Ramarao CS, Ward GE, Bentley JK, Garbers DL. A peptide associated with eggs causes a mobility shift in a major plasma membrane protein of spermatozoa. J Biol Chem. 1984 Dec 10;259(23):14874-9. PubMed PMID: 6150045.10: Kotzur N, Briand B, Beyermann M, Hagen V. Wavelength-selective photoactivatable protecting groups for thiols. J Am Chem Soc. 2009 Nov 25;131(46):16927-31. doi: 10.1021/ja907287n. PubMed PMID: 19863095.1
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