1639-60-7|Propoxyphene Hydrochloride|[(2S,3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate;hydrochloride|-范德生物科技公司

Propoxyphene Hydrochloride

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names：
[(2S,3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate;hydrochloride
CAS号：
1639-60-7
MDL Number：
MF(分子式)： C22H30ClNO2 MW(分子量)： 375.93
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	[(2S,3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate;hydrochloride
英文别名	Propoxyphene Hydrochloride; Darvon; Algaphan; Deprancol; Develin; Dextropropoxyphene hydrochloride; D-Propoxyphene.
CAS号	1639-60-7
Inchi	InChI=1S/C22H29NO2.ClH/c1-5-21(24)25-22(18(2)17-23(3)4,20-14-10-7-11-15-20)16-19-12-8-6-9-13-19;/h6-15,18H,5,16-17H2,1-4H3;1H/t18-,22+;/m1./s1
InchiKey	QMQBBUPJKANITL-MYXGOWFTSA-N
分子式 Formula	C22H30ClNO2
分子量 Molecular Weight	375.93
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Propoxyphene Hydrochloride(CAS:1639-60-7 ):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Propoxyphene HCl, also known as Dextropropoxyphene, is discontinued (DEA controlled substance). It is an analgesic in the opioid category. It is an optical isomer of levopropoxyphene intended to treat mild pain and cough . The drug has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Tashjian EA, Richter KJ. The value of propoxyphene hydrochloride (Darvon) forthe treatment of hyperhidrosis in the spinal cord injured patient: an anecdotalexperience and case reports. Paraplegia. 1985 Dec;23(6):349-53. PubMed PMID:4080410.

[2]Heaney RM. Left bundle branch block associated with propoxyphene hydrochloridepoisoning. Ann Emerg Med. 1983 Dec;12(12):780-2. PubMed PMID: 6650949.

[3] Christensen FN, Hansen FY, Bechgaard H. Mathematical model for in vitro drugrelease from controlled release dosage forms applied to propoxyphenehydrochloride pellets. J Pharm Sci. 1982 Jun;71(6):694-9. PubMed PMID: 7097537.

[4] Baggesen S, Bechgaard H. In vitro evaluation of two controlled releasepropoxyphene hydrochloride formulations. Influence of the composition ofdissolution media on drug release. Pharm Acta Helv. 1980;55(11-12):312-5. PubMedPMID: 7208533.

[5] Trop D, Kenny L, Grad BR. Comparison of nefopam hydrochloride and propoxyphenehydrochloride in the treatment of postoperative pain. Can Anaesth Soc J. 1979Jul;26(4):296-304. PubMed PMID: 509346.

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