16545-11-2|Guamecycline|N-[[4-[[(Aminoiminomethyl)amino](imino)methyl]piperazin-1-yl]methyl]tetracycline|-范德生物科技公司

Guamecycline

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names：
N-[[4-[[(Aminoiminomethyl)amino](imino)methyl]piperazin-1-yl]methyl]tetracycline
CAS号：
16545-11-2
MDL Number：
MF(分子式)： C29H38N8O8 MW(分子量)： 626.671
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Guamecycline
英文别名	Guamecycline; NSC 118695; NSC-118695; NSC118695; N1,N1-Diethyleniminobiguanidomethyltetracycline; Tetrabiguanide; Xanthomycin A; Xantomicina;
CAS号	16545-11-2
Inchi	InChI=1S/C29H38N8O8/c1-28(44)13-5-4-6-16(38)17(13)21(39)18-14(28)11-15-20(35(2)3)22(40)19(24(42)29(15,45)23(18)41)25(43)33-12-36-7-9-37(10-8-36)27(32)34-26(30)31/h4-6,14-15,20,38,40-41,44-45H,7-12H2,1-3H3,(H,33,43)(H5,30,31,32,34)/t14-,15-,20-,28+,29-/m0/s1
InchiKey	DIRJDIBCAHCCFL-AQFAATAFSA-N
分子式 Formula	C29H38N8O8
分子量 Molecular Weight	626.671
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Guamecycline(CAS:16545-11-2 ):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Guamecycline, also known as NSC 118695, is an antibiotic with Antitumor Activity.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Logico G, Favero S, Piva A, Conz A. [Bacterial activity and salivary concentration of xanthocycline]. G Stomatol Ortognatodonzia. 1984 Oct-Dec;3(4):718-9. Italian. PubMed PMID: 6443215.

[2]Nishimura T, Kitajima J, Omura S, Tanaka N. Antitumor activity of an antibiotic identical with or closely related to xanthomycin A. J Antibiot (Tokyo). 1981 Jul;34(7):856-61. PubMed PMID: 7287588.

[3] Bocarnea C, Duminica A. [Guamecycline in the treatment of acute pneumopathies. Clinical research and comparison with other tetracyclines]. Minerva Med. 1972 Nov 21;63(83):4533-6. Italian. PubMed PMID: 4565314.

[4] Lányi M, Hordós A, Major T, Tarján E, Zolnay E. Guamecycline in bronchial infections due to Diplococcus pneumoniae. Panminerva Med. 1972 Jan-Feb;14(1-2):24-9. PubMed PMID: 4156979.

[5] Bottero A, Pellegrini R, Lops M. [Effects of aerosol administration of guamecycline in patients with broncho-pulmonary diseases]. Epatologia. 1971 Jan-Feb;17(1):85-95. Italian. PubMed PMID: 5147865.

6: Toshkov A, Slavcheva E. [Inhibiting effects of guamecycline and of tetracycline hydrochloride on antibody-producing cells of the spleen and lymph nodes]. Arch Sci Med (Torino). 1971 Jan-Mar;128(1):43-5. Italian. PubMed PMID: 5106864.7: Bottoni P, Lombardi G. [Antibiotics in the prevention of exacerbation of chronic bronchitis. Comparative clinical study with guamecycline and tetracycline HCl]. G Ital Mal Torace. 1970 Jul-Aug;24(4):197-200 passim. Italian. PubMed PMID: 5516897.8: Domenichini E, Carbonera D, Cambieri F, Ruozi P, Pellegrini R. Guamecycline and the bronchopulmonary system. Measurement of antibiotic levels in bronchial secretion. Farmaco Prat. 1969 Oct;24(10):663-70. PubMed PMID: 5361894.9: Lodigiani E, Ruozi P. [Biliary elimination of N1,N1-diethyleniminobiguanido-methyl-tetracicline in humans]. Arch Sci Med (Torino). 1969 Sep;126(9):618-22. Italian. PubMed PMID: 17340814.10: Ruozi P, Pellegrini R, Piazza G. [Human bronchial epithelium appearance after treatment with guamecycline. Electron microscopy study]. G Ital Mal Torace. 1969 Jul-Aug;23(4):173-82. Italian. PubMed PMID: 5404444.1

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