19326-29-5|Etamiphylline Camsylate|7-(2-(diethylamino)ethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione ((1S)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate|-范德生物科技公司

Etamiphylline Camsylate

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names：
7-(2-(diethylamino)ethyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione ((1S)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
CAS号：
19326-29-5
MDL Number：
MF(分子式)： C23H37N5O6S MW(分子量)： 511.638
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Etamiphylline Camsylate
英文别名	Etamiphylline Camsilate; R-3588; R 3588; R3588; Milliphylline; Soluphyline; Parephyllin;
CAS号	19326-29-5
Inchi	InChI=1S/C13H21N5O2.C10H16O4S/c1-5-17(6-2)7-8-18-9-14-11-10(18)12(19)16(4)13(20)15(11)3;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h9H,5-8H2,1-4H3;7H,3-6H2,1-2H3,(H,12,13,14)/t;7?,10-/m.1/s1
InchiKey	KVZYKZBYZVKXNI-FHIDHQGESA-N
分子式 Formula	C23H37N5O6S
分子量 Molecular Weight	511.638
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Etamiphylline Camsylate(CAS:19326-29-5 ):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Etamiphylline Camsylate, also known as R-3588, is a drug used to treat chronic obstructive pulmonary disease (COPD).
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Wieder ME, Brown PR, Grainger L, Teale P. Identification of etamiphylline and metabolites in equine plasma and urine by accurate mass and liquid chromatography/tandem mass spectrometry. Drug Test Anal. 2010 Jun;2(6):271-7. doi: 10.1002/dta.133. PubMed PMID: 20564606.

[2]Fennell C. Nitrite toxicity in cattle and etamiphylline camsylate. Vet Rec. 1979 Jan 6;104(1):22. PubMed PMID: 433104.

[3] Dumasia MC, Teale P. N-deethylation and N-oxidation of etamiphylline: identification of etamiphylline-N-oxide in greyhound urine by high performance liquid chromatography-mass spectrometry. J Pharm Biomed Anal. 2005 Jan 4;36(5):1085-91. PubMed PMID: 15620536.

[4] Elghazali M, Wasfi IA, Al Katheeri NA, Hadi AA, Hussein MM. The pharmacokinetics, metabolism and urinary detection time of etamiphylline in camels after intramuscular administration. J Vet Pharmacol Ther. 2002 Feb;25(1):43-8. PubMed PMID: 11874526.

[5] Gleeson M, Haigh AL, Molony V, Anderson LS. Ventilatory and cardiovascular responses of the unanaesthetized chicken, Gallus domesticus, to the respiratory stimulants etamiphylline and almitrine. Comp Biochem Physiol C. 1985;81(2):367-74. PubMed PMID: 2861956.

6: Addis GJ. Absence of bronchodilatory effect from etamiphylline. Lancet. 1984 May 12;1(8385):1083. PubMed PMID: 6144017.7: Vazquez C, Labayru T, Rodriguez-Soriano J. Poor bronchodilator effect of oral etamiphylline in asthmatic children. Lancet. 1984 Apr 21;1(8382):914. PubMed PMID: 6143224.8: Vázquez C, Labayru MT. [Comparative study of the effect of a single oral dose of theophylline and etamiphyllin in children with asthma]. An Esp Pediatr. 1984 Nov 30;21(8):739-46. Spanish. PubMed PMID: 6529027.9: Atwell RB. The use of alpha blockade in the treatment of congestive heart failure associated with dirofilariasis and mitral valvular incompetence. Vet Rec. 1979 Feb 10;104(6):114-6. PubMed PMID: 452344.10: Perkins MN, Stone TW. Aminophylline and theophylline derivatives as antagonists of neuronal depression by adenosine: a microiontophoretic study. Arch Int Pharmacodyn Ther. 1980 Aug;246(2):205-14. PubMed PMID: 7436627.1

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