299-42-3|Ephedrine|(1R,2S)-2-(methylamino)-1-phenylpropan-1-ol|-范德生物科技公司

Ephedrine

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names：
(1R,2S)-2-(methylamino)-1-phenylpropan-1-ol
CAS号：
299-42-3
MDL Number：
MF(分子式)： C10H15NO MW(分子量)： 165.24
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Ephedrine
英文别名	Bronkaid, Primatene; L-Ephedrine; (-)-Ephedrine; 299-42-3; Ephedrin; Ephedrol
CAS号	299-42-3
Inchi	InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m0/s1
InchiKey	KWGRBVOPPLSCSI-WPRPVWTQSA-N
分子式 Formula	C10H15NO
分子量 Molecular Weight	165.24
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Ephedrine(CAS:299-42-3 ):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Ephedrine is a phenethylamine used for asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. Ephedrine works by turning on α and β adrenergic receptors that may also enhance release of norepinephrine. It has become less extensively used with the advent of more selective agonists.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Mohta M, Aggarwal M, Sethi AK, Harisinghani P, Guleria K. Randomized double-blind comparison of ephedrine and phenylephrine for management of post-spinal hypotension in potential fetal compromise. Int J Obstet Anesth. 2016 Feb 2[1]pii: S0959-289X(16)00033-9. doi: 10.1016/j.ijoa.2016.02.004. [Epub ahead of print] PubMed PMID: 27020488.

[2]Nivatpumin P, Thamvittayakul V. Ephedrine versus ondansetron in the prevention of hypotension during cesarean delivery: a randomized, double-blind, placebo-controlled trial. Int J Obstet Anesth. 2016 Feb 21. pii: S0959-289X(16)00032-7. doi: 10.1016/j.ijoa.2016.02.003. [Epub ahead of print] PubMed PMID: 27020487.

[3] Oshima N, Yamashita T, Hyuga S, Hyuga M, Kamakura H, Yoshimura M, Maruyama T, Hakamatsuka T, Amakura Y, Hanawa T, Goda Y. Efficiently prepared ephedrine alkaloids-free Ephedra Herb extract: a putative marker and antiproliferative effects. J Nat Med. 2016 Mar 14. [Epub ahead of print] PubMed PMID: 26976141.

[4] Hyuga S, Hyuga M, Oshima N, Maruyama T, Kamakura H, Yamashita T, Yoshimura M, Amakura Y, Hakamatsuka T, Odaguchi H, Goda Y, Hanawa T. Ephedrine alkaloids-free Ephedra Herb extract: a safer alternative to ephedra with comparable analgesic, anticancer, and anti-influenza activities. J Nat Med. 2016 Mar 4. [Epub ahead of print] PubMed PMID: 26943796.

[5] Armoiry X, Carry PY, Lehot JJ, Michel C, Aulagner G, Piriou V. Estimated economic impact of pre-filled ephedrine syringes in the operating room. Acta Anaesthesiol Scand. 2016 Mar 3. doi: 10.1111/aas.12718. [Epub ahead of print] PubMed PMID: 26935817.

6: Ituk US, Cooter M, Habib AS. Retrospective comparison of ephedrine and phenylephrine for the treatment of spinal anesthesia induced hypotension in pre-eclamptic patients. Curr Med Res Opin. 2016 Mar 29:1-4. [Epub ahead of print] PubMed PMID: 26928367.7: Almustafa MM, Al-Oweidi AS, Al-Zaben KR, Qudaisat IY, Abu-Halaweh S, Alghanem SM, Massad IM, Samarah W, Al-Shaer RA, Ismail S, Khazawla F. Ephedrine requirements during spinal anesthesia for cesarean delivery in Jordanian parturients: association with b2 adrenoceptor gene variants. Ann Saudi Med. 2016 Jan-Feb;36(1):29-36. doi: 10.5144/0256-4947.2016.29. PubMed PMID: 26922685.8: Hong A, Jeong C, Jang H, Choi MC, Heo J, Kim NJ. Fluorescence-detected circular dichroism spectroscopy of jet-cooled ephedrine. Phys Chem Chem Phys. 2016 Mar 9;18(11):7762-7. doi: 10.1039/c5cp07438j. PubMed PMID: 26910410.9: Miao L, Liu Y, Li H, Qi Y, Lu F. Two-dimensional correlation infrared spectroscopy applied to the identification of ephedrine and pseudoephedrine in illegally adulterated slimming herbal products. Drug Test Anal. 2016 Feb 17. doi: 10.1002/dta.1963. [Epub ahead of print] PubMed PMID: 26888635.10: Unlugenc H, Turktan M, Evruke IC, Gunduz M, Burgut R, Yapicioglu-Yildizdas H, Isik G. RAPID FLUID ADMINISTRATION AND THE INCIDENCE OF HYPOTENSION INDUCED BY SPINAL ANESTHESIA AND EPHEDRINE REQUIREMENT: THE EFFECT OF CRYSTALLOID VERSUS COLLOID COLOADING. Middle East J Anaesthesiol. 2015 Oct;23(3):273-81. PubMed PMID: 26860016.

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