52932-64-6|Cinodine|Cinodine|-范德生物科技公司

Cinodine

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names：
Cinodine
CAS号：
52932-64-6
MDL Number：
MF(分子式)： C37H60ClN13O13 MW(分子量)： 930.41
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	(E)-N-(3-((4-aminobutyl)amino)propyl)-3-(4-(((2R,3R,4S,5S,6R)-3-guanidino-4-hydroxy-5-(3-((2S,3R,4R,5R)-4-hydroxy-5-(((3aS,6S,7R,7aR)-2-oxo-7-ureidohexahydro-2H-pyrano[4,3-d]oxazol-6-yl)oxy)-3-ureidotetrahydro-2H-pyran-2-yl)ureido)-6-methyltetrahydro-2H-pyran-2-yl)oxy)phenyl)acrylamide hydrochloride
英文别名	Cinodine; BM 123 gamma; BM-123 gamma; BM123 gamma; LL-BM 123 gamma; Antibiotic BM 123 gamma;
CAS号	52932-64-6
Inchi	InChI=1S/C37H59N13O13.ClH/c1-17-23(29(53)27(45-33(39)40)32(60-17)61-19-8-5-18(6-9-19)7-10-22(51)44-14-4-13-43-12-3-2-11-38)48-36(56)50-30-26(47-35(42)55)28(52)21(16-58-30)62-31-25(46-34(41)54)24-20(15-59-31)63-37(57)49-24;/h5-10,17,20-21,23-32,43,52-53H,2-4,11-16,38H2,1H3,(H,44,51)(H,49,57)(H4,39,40,45)(H3,41,46,54)(H3,42,47,55)(H2,48,50,56);1H/b10-7+;/t17-,20-,21-,23-,24+,25-,26-,27-,28+,29+,30+,31+,32-;/m1./s1
InchiKey	ZSPJOQBEUKQIIA-KWUZUVEWSA-N
分子式 Formula	C37H60ClN13O13
分子量 Molecular Weight	930.41
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Cinodine(CAS:52932-64-6):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Cinodine is a glycocinnamoylspermidine antibiotic; gyrase inhibitor found in Nocardia.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Greenstein M, Speth JL, Maiese WM. Mechanism of action of cinodine, a glycocinnamoylspermidine antibiotic. Antimicrob Agents Chemother. 1981 Oct;20(4):425-32. PubMed PMID: 6177279; PubMed Central PMCID: PMC181719.

[2]Chiu SH, Fiala R, Kennett R, Wozniak L, Bullock MW. Biosynthesis of the glycocinnamoylspermidine antibiotic, cinodine. J Antibiot (Tokyo). 1984 Sep;37(9):1000-6. PubMed PMID: 6501101.

[3] Osburne MS, Maiese WM, Greenstein M. In vitro inhibition of bacterial DNA gyrase by cinodine, a glycocinnamoylspermidine antibiotic. Antimicrob Agents Chemother. 1990 Jul;34(7):1450-2. PubMed PMID: 2167040; PubMed Central PMCID: PMC176000.

[4] Osburne MS. Characterization of a cinodine-resistant mutant of Escherichia coli. J Antibiot (Tokyo). 1995 Nov;48(11):1359-61. PubMed PMID: 8557583.

[5] Chen RH, Whittern DN, Buko AM, McAlpine JB. Coumamidines, new broad spectrum antibiotics of the cinodine type. II. Isolation and structural elucidation. J Antibiot (Tokyo). 1989 Apr;42(4):533-7. PubMed PMID: 2498267.

6: Jackson M, Karwowski JP, Theriault RJ, Kohl WL, Humphrey PE, Sunga GN, Swanson SJ, Villarreal RM. Coumamidines, new broad spectrum antibiotics of the cinodine type. I. Discovery, taxonomy of the producing organism and fermentation. J Antibiot (Tokyo). 1989 Apr;42(4):527-32. PubMed PMID: 2498266.7: Tsou HR, Fiala RR, Mowery PC, Bullock MW. Biosynthesis of the spermidine and guanidino units in the glycocinnamoylspermidine antibiotic cinodine. J Antibiot (Tokyo). 1984 Nov;37(11):1382-7. PubMed PMID: 6511665.8: Chiu SH, Fiala R, Bullock MW. Biosynthesis of the spermidine moiety of glycocinnamoylspermidine antibiotic cinodine. J Antibiot (Tokyo). 1984 Sep;37(9):1079-81. PubMed PMID: 6501105.9: McKay MJ, Nguyen HM. Recent developments in glycosyl urea synthesis. Carbohydr Res. 2014 Feb 19;38

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