5793-89-5|葡萄糖二酸鈣|Glucaric acid calcium salt (Calcium saccharate), beta-glucuronidase inhibitor|-范德生物科技公司

葡萄糖二酸鈣

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names：
Glucaric acid calcium salt (Calcium saccharate), beta-glucuronidase inhibitor
CAS号：
5793-89-5
MDL Number：
MF(分子式)： C6H16CaO12 MW(分子量)： 320.26
EINECS:611-592-0 Reaxys Number:
Pubchem ID:11954337 Brand:BIOFOUNT

葡萄糖二酸鈣(5793-89-5,Glucaric acid calcium salt)是一种β-葡萄糖醛酸酶抑制剂，可以刺激分化和抑制增殖，显示体内的化学预防和抗肿瘤作用。

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中文别名	葡萄糖二酸鈣(5793-89-5);Calcium saccharate;葡萄糖酸钙盐;β-葡萄糖醛酸酶抑制剂
英文别名	Glucaric acid calcium salt (Calcium saccharate), beta-glucuronidase inhibitor(5793-89-5);Calcium D-saccharate tetrahydrate; L-Gularic Acid;
CAS号	5793-89-5
SMILES	O=C([O-])[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.[H]O[H].[H]O[H].[H]O[H].[H]O[H].[Ca+2]
Inchi	InChI=1S/C6H10O8.Ca.4H2O/c7-1(3(9)5(11)12)2(8)4(10)6(13)14;;;;;/h1-4,7-10H,(H,11,12)(H,13,14);;4*1H2/q;+2;;;;/p-2/t1-,2-,3-,4+;;;;;/m0...../s1
InchiKey	ZQWFSIZRQANUDA-WQMSYZFBSA-L
分子式 Formula	C6H16CaO12
分子量 Molecular Weight	320.26
闪点 FP	No data available
熔点 Melting point	185℃
沸点 Boiling point	No data available
Polarizability极化度	No data available
密度 Density
蒸汽压 Vapor Pressure	No data available
溶解度Solubility
性状	白色至灰白色固体粉末
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	葡萄糖二酸鈣(5793-89-5,Glucaric acid calcium salt)仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Calcium saccharate is an oxidized non-cyclic hexose sugar. It may inhibit carcinogenesis and proliferation of cancer cells.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示	P264处理后彻底清洗+P280戴防护手套/穿防护服/戴防护眼罩/戴防护面具+P305如果进入眼睛+P351用水小心冲洗几分钟+P338取出隐形眼镜（如果有）并且易于操作,继续冲洗+P337如果眼睛刺激持续+P313获得医疗建议/护理
安全声明	H315 H319 H335
安全防护	P264 P302+P352 P304+P340 P305+P351+P338 P332+P313 P337+P313
备注

[1]Garcia AC, Vavrusova M, Skibsted LH. Calcium d-Saccharate: Aqueous Solubility, Complex Formation, and Stabilization of Supersaturation. J Agric Food Chem. 2016 Mar 23;64(11):2352-60. doi: 10.1021/acs.jafc.6b00166. Epub 2016 Mar 9. PubMed PMID: 26934422.

[2]Agarwal R, Kusek JW, Pappas MK. A randomized trial of intravenous and oral iron in chronic kidney disease. Kidney Int. 2015 Oct;88(4):905-14. doi: 10.1038/ki.2015.163. Epub 2015 Jun 17. PubMed PMID: 26083656; PubMed Central PMCID: PMC4589436.

[3] Calcium-D-glucarate. Altern Med Rev. 2002 Aug;7(4):336-9. Review. PubMed PMID: 12197785.

[4] Wang C, Graham DJ, Kane RC, Xie D, Wernecke M, Levenson M, MaCurdy TE, Houstoun M, Ryan Q, Wong S, Mott K, Sheu TC, Limb S, Worrall C, Kelman JA, Reichman ME. Comparative Risk of Anaphylactic Reactions Associated With Intravenous Iron Products. JAMA. 2015 Nov 17;314(19):2062-8. doi: 10.1001/jama.2015.15572. PubMed PMID: 26575062.

[5] Shi Q, Leng W, Wazir R, Li J, Yao Q, Mi C, Yang J, Xing A. Intravenous Iron Sucrose versus Oral Iron in the Treatment of Pregnancy with Iron Deficiency Anaemia: A Systematic Review. Gynecol Obstet Invest. 2015;80(3):170-8. doi: 10.1159/000376577. Epub 2015 Mar 25. Review. PubMed PMID: 25824489.

6: Macdougall IC, Strauss WE, McLaughlin J, Li Z, Dellanna F, Hertel J. A randomized comparison of ferumoxytol and iron sucrose for treating iron deficiency anemia in patients with CKD. Clin J Am Soc Nephrol. 2014 Apr;9(4):705-12. doi: 10.2215/CJN.05320513. Epub 2014 Jan 23. PubMed PMID: 24458078; PubMed Central PMCID: PMC3974353.7: Pieracci FM, Stovall RT, Jaouen B, Rodil M, Cappa A, Burlew CC, Holena DN, Maier R, Berry S, Jurkovich J, Moore EE. A multicenter, randomized clinical trial of IV iron supplementation for anemia of traumatic critical illness*. Crit Care Med. 2014 Sep;42(9):2048-57. doi: 10.1097/CCM.0000000000000408. PubMed PMID: 24797376.8: Jiang J, Li Y, Feng Z, Yang Y, Zhang P. Glucaric acids from Leonurus japonicus. Fitoterapia. 2015 Dec;107:85-9. doi: 10.1016/j.fitote.2015.10.007. Epub 2015 Oct 23. PubMed PMID: 26526024.9: Qiu Y, Fang F, Du G, Chen J. [Progress in glucaric acid]. Sheng Wu Gong Cheng Xue Bao. 2015 Apr;31(4):481-90. Review. Chinese. PubMed PMID: 26380405.10: Rebel A, Beck A, Efron P, Bavry AA, Ang D. Successful Rescue Therapy for Severe Acute Anemia: Managing the Critically Ill Jehovah's Witness. Am Surg. 2015 Jun;81(6):E263-5. PubMed PMID: 26031262.1

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