1071992-57-8|AT-406 HCl|(5S,8S,10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide hydrochloride|-范德生物科技公司

AT-406 HCl

NMR下载 COA and HPLC MSDS下载
names：
(5S,8S,10aR)-N-benzhydryl-5-((S)-2-(methylamino)propanamido)-3-(3-methylbutanoyl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocine-8-carboxamide hydrochloride
CAS号：
1071992-57-8
MDL Number：
MF(分子式)： C32H44ClN5O4 MW(分子量)： 597.31
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)

大包装询价提供各种包装，敬请垂询
收藏商品商品点评加入购物车立即购买

快速询价

收起

你想询价的产品

*产品名称：

CAS号：

产品编号：

需求描述：

请准确填写您的联系方式，以便为您提供最好的服务。

*公司名称：

*电子邮箱：

联系人：

*电话：

*验证码：

询价

中文别名	AT-406 HCl
英文别名	AT-406; AT 406; AT406; D 1143; Debio 1143; N65WC8PXDD; SM 406.
CAS号	1071992-57-8
Inchi	InChI=1S/C32H43N5O4.ClH/c1-21(2)19-28(38)36-18-17-25-15-16-27(37(25)32(41)26(20-36)34-30(39)22(3)33-4)31(40)35-29(23-11-7-5-8-12-23)24-13-9-6-10-14-24;/h5-14,21-22,25-27,29,33H,15-20H2,1-4H3,(H,34,39)(H,35,40);1H/t22-,25+,26-,27-;/m0./s1
InchiKey	DBXTZCYPHKJCHF-ZZPLZQMBSA-N
分子式 Formula	C32H44ClN5O4
分子量 Molecular Weight	597.31
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	AT-406 HCl(CAS:1071992-57-8 ):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	AT406 (SM-406) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Fu PY, Hu B, Ma XL, Yang ZF, Yu MC, Sun HX, Huang A, Zhang X, Wang J, Hu ZQ, Zhou CH, Tang WG, Ning R, Xu Y, Zhou J. New insight into BIRC

3: A novel prognostic indicator and a potential therapeutic target for liver cancer. J Cell Biochem. 2018 Oct 28. doi: 10.1002/jcb.27890. [Epub ahead of print] PubMed PMID: 30368883.

[3]Tokuhara Y, Shukuya K, Tanaka M, Sogabe K, Ejima Y, Hosokawa S, Ohsaki H, Morinishi T, Hirakawa E, Yatomi Y, Shimosawa T. Absorbance measurements of oxidation of homogentisic acid accelerated by the addition of alkaline solution with sodium hypochlorite pentahydrate. Sci Rep. 2018 Jul 27;8(1):11364. doi: 10.1038/s41598-018-29769-w. PubMed PMID: 30054539; PubMed Central PMCID: PMC6063975.

[4]Martínez Gámez MA, Vallejo H MA, Kiryanov AV, Licea-Jiménez L, Lucio M JL, Pérez-García SA. Fluorescence properties of Yb(3+)-Er(3+) co-doped phosphate glasses containing silver nanoparticles. Methods Appl Fluoresc. 2018 Feb 15;6(2):024005. doi: 10.1088/2050-6120/aaab6c. PubMed PMID: 29447118.

[5] Martinez Gamez MA, Vallejo M, Kir'yanov AV, Licea Jiménez L, Lucio Martínez JL, Pérez-García SA. Fluorescence properties of Yb³⁺ - Er³⁺ co-doped phosphate glasses containing silver nanoparticles. Methods Appl Fluoresc. 2018 Jan 30. doi: 10.1088/2050-6120/aaab6c. [Epub ahead of print] PubMed PMID: 29378978.

5: Toubai T, Rossi C, Oravecz-Wilson K, Liu C, Zajac C, Wu SJ, Sun Y, Fujiwara H, Tamaki H, Peltier D, Riwes M, Henig I, Brabbs S, Duckett CS, Wang S, Reddy P. IAPs protect host target tissues from graft-versus-host disease in mice. Blood Adv. 2017 Aug 16;1(19):1517-1532. doi: 10.1182/bloodadvances.2017004242. eCollection 2017 Aug 22. PubMed PMID: 29296793; PubMed Central PMCID: PMC5728459.

对不起，暂无产品评价！

MSDS

SDS 1.0 中文

展开

SDS 1.0 英文

展开