79811-16-8|WW-781|Benzenesulfonic acid, 4-(4-(5-(1,3-dibutyltetrahydro-2,4,6-trioxo-5(2H)-pyrimidinylidene)-1,3-pentadienyl)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)-|-范德生物科技公司

WW-781

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names：
Benzenesulfonic acid, 4-(4-(5-(1,3-dibutyltetrahydro-2,4,6-trioxo-5(2H)-pyrimidinylidene)-1,3-pentadienyl)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)-
CAS号：
79811-16-8
MDL Number：
MF(分子式)： C27H32N4O7S MW(分子量)： 556.634
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Benzenesulfonic acid, 4-(4-(5-(1,3-dibutyltetrahydro-2,4,6-trioxo-5(2H)-pyrimidinylidene)-1,3-pentadienyl)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)-
英文别名	WW-781; NK 2935; WW 781; WW781
CAS号	79811-16-8
SMILES	O=S(C1=CC=C(N2N=C(C)C(/C=C/C=C/C=C(C(N3CCCC)=O)\C(N(CCCC)C3=O)=O)C2=O)C=C1)(O)=O
Inchi	InChI=1S/C27H32N4O7S/c1-4-6-17-29-24(32)23(25(33)30(27(29)35)18-7-5-2)12-10-8-9-11-22-19(3)28-31(26(22)34)20-13-15-21(16-14-20)39(36,37)38/h8-16,22H,4-7,17-18H2,1-3H3,(H,36,37,38)/b10-8+,11-9+
InchiKey	ZSJQWOYTDGVNSG-GFULKKFKSA-N
分子式 Formula	C27H32N4O7S
分子量 Molecular Weight	556.634
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	WW-781(CAS:79811-16-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	WW-781 is used to measure action potential propagation in the heart.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Raha NM, Spinelli LJ, Knauf PA. WW-781, a potent reversible inhibitor of red cell Cl- flux, binds to band 3 by a two-step mechanism. Am J Physiol. 1993 Aug;265(2 Pt 1):C521-32. PubMed PMID: 8368278.

[2]Freedman JC, Novak TS. Membrane potentials associated with Ca-induced K conductance in human red blood cells: studies with a fluorescent oxonol dye, WW 781. J Membr Biol. 1983;72(1-2):59-74. PubMed PMID: 6406671.

[3] Mizutani K, Shimoi T, Kitamura Y, Ogawa H, Oka K. Identification of two types of synaptic activity in the earthworm nervous system during locomotion. Neuroscience. 2003;121(2):473-8. PubMed PMID: 14522005.

[4] Perez-Cornejo P, Arreola J, Law FY, Schultz JB, Knauf PA. Volume-sensitive chloride channels do not mediate activation-induced chloride efflux in human neutrophils. J Immunol. 2004 Jun 1;172(11):6988-93. PubMed PMID: 15153519.

[5] Konnerth A, Orkand PM, Orkand RK. Optical recording of electrical activity from axons and glia of frog optic nerve: potentiometric dye responses and morphometrics. Glia. 1988;1(3):225-32. PubMed PMID: 2852172.

6: Wolfbeis OS, Opitz D, Werner T, Ouart A. Chiroptic recognition of potassium ion. J Mol Recognit. 2001 Jan-Feb;14(1):13-7. PubMed PMID: 11180558.7: Dillon S, Morad M. A new laser scanning system for measuring action potential propagation in the heart. Science. 1981 Oct 23;214(4519):453-6. PubMed PMID: 6974891.8: Fillette F, Nassif G, Lascault G. [Electric activation of the heart using laser spectrometry. 1. Study of transmembrane action potentials using optical technics]. Arch Mal Coeur Vaiss. 1985 Sep;78(9):1418-24. French. PubMed PMID: 3936445.9: Pratap PR, Novak TS, Freedman JC. Two mechanisms by which fluorescent oxonols indicate membrane potential in human red blood cells. Biophys J. 1990 Apr;57(4):835-49. PubMed PMID: 1693090; PubMed Central PMCID: PMC1280784.10: Fillette F, Nassif G. A study of electrical activation of the heart by laser spectrometry. An optical study of cellular action potentials. Int J Card Imaging. 1987;2(3):165-72. PubMed PMID: 3429940.1

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