132373-81-0|Vamicamide|2-Pyridineacetamide, alpha-(2-(dimethylamino)propyl)-alpha-phenyl-, (R*,R*)-(+-)-|-范德生物科技公司

Vamicamide

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names：
2-Pyridineacetamide, alpha-(2-(dimethylamino)propyl)-alpha-phenyl-, (R*,R*)-(+-)-
CAS号：
132373-81-0
MDL Number：
MF(分子式)： C18H23N3O MW(分子量)： 297.402
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	2-Pyridineacetamide, alpha-(2-(dimethylamino)propyl)-alpha-phenyl-, (R,R)-(+-)-
英文别名	Vamicamide;
CAS号	132373-81-0
Inchi	InChI=1S/C18H23N3O/c1-14(21(2)3)13-18(17(19)22,15-9-5-4-6-10-15)16-11-7-8-12-20-16/h4-12,14H,13H2,1-3H3,(H2,19,22)/t14-,18-/m1/s1
InchiKey	BWNLUIXQIHPUGO-RDTXWAMCSA-N
分子式 Formula	C18H23N3O
分子量 Molecular Weight	297.402
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Vamicamide(CAS:132373-81-0):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Vamicamide is a biochemical.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Cadranel JF, Boujenah JL, Bourlière M, Fontanges T, Pol S, Trepo C, Ouzan D. Satisfaction of patients treated for chronic hepatitis C with the peginterferon alfa-2b pen device: the VISA observational study. Gastroenterol Clin Biol. 2007 Feb;31(2):180-4. PubMed PMID: 17347628.

[2]Yono M, Yoshida M, Takahashi W, Inadome A, Ueda S. Comparison of the effects of novel antimuscarinic drugs on human detrusor smooth muscle. BJU Int. 2000 Oct;86(6):719-25. PubMed PMID: 11069384.

[3] Yamamoto T, Honbo T, Tokoro K, Kojimoto Y, Kodama R, Ohtsuka M, Shimomura K. General pharmacology of the new antimuscarinic compound vamicamide. Arzneimittelforschung. 1995 Dec;45(12):1274-84. PubMed PMID: 8595084.

[4] Yamamoto T, Koibuchi Y, Miura S, Sawada T, Ozaki R, Esumi K, Ohtsuka M. Effects of vamicamide on urinary bladder functions in conscious dog and rat models of urinary frequency. J Urol. 1995 Dec;154(6):2174-8. PubMed PMID: 7500484.

[5] Oyasu H, Nakanishi I, Tanaka A, Murano K, Matsuo M. Conformational studies on the four stereoisomers of the novel anticholinergic 4-(dimethylamino)-2-phenyl-2-(2-pyridyl)pentanamide. J Comput Aided Mol Des. 1995 Apr;9(2):171-80. PubMed PMID: 7608748.

6: Oyasu H, Yamamoto T, Sato N, Sawada T, Ozaki R, Mukai T, Ozaki T, Nishii M, Sato H, Fujiwara T, et al. Urinary bladder-selective action of the new antimuscarinic compound vamicamide. Arzneimittelforschung. 1994 Nov;44(11):1242-9. PubMed PMID: 7848339.7: Oyasu H, Nagano M, Akahane A, Tomoi M, Tada T, Matsuo M. Synthesis and anticholinergic activity of the four stereoisomers of 4-(dimethylamino)-2-phenyl-2-(2-pyridyl)pentanamide. J Med Chem. 1994 Apr 29;37(9):1378-81. PubMed PMID: 8176715.8: Suzuki A, Takagaki S, Suzuki H, Noda K. Determination of the R,R- and S,S-enantiomers of vamicamide in human serum and urine by high-performance liquid chromatography on a Chiral-AGP column. J Chromatogr. 1993 Aug 11;617(2):279-84. PubMed PMID: 8408394.

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