126433-07-6|Tyrphostin 51|2-Amino-1,1,3-tricyano-4-(3',4',5'-trihydroxyphenyl)butadiene|-范德生物科技公司

Tyrphostin 51

NMR下载 COA and HPLC MSDS下载
names：
2-Amino-1,1,3-tricyano-4-(3',4',5'-trihydroxyphenyl)butadiene
CAS号：
126433-07-6
MDL Number：
MF(分子式)： C13H8N4O3 MW(分子量)： 268.232
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)

大包装询价提供各种包装，敬请垂询
收藏商品商品点评加入购物车立即购买

快速询价

收起

你想询价的产品

*产品名称：

CAS号：

产品编号：

需求描述：

请准确填写您的联系方式，以便为您提供最好的服务。

*公司名称：

*电子邮箱：

联系人：

*电话：

*验证码：

询价

中文别名	2-Amino-1,1,3-tricyano-4-(3',4',5'-trihydroxyphenyl)butadiene
英文别名	Tyrphostin 51; Tyrphostin A 51; Tyrphostin A-51; Tyrphostin A51.
CAS号	126433-07-6
Inchi	InChI=1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+
InchiKey	JKNOYWVMHPMBEL-UNXLUWIOSA-N
分子式 Formula	C13H8N4O3
分子量 Molecular Weight	268.232
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Tyrphostin 51(CAS:126433-07-6):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Tyrphostin 51 is a potent inhibitor of EGFR (EGF receptor) kinase activity
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Chung FY, Song HJ, Park SY, Jang HS, Kim DS, Sim SS, Sohn UD. Signaling mechanisms of sphingosine 1-phosphate-induced ERK1/2 activation in cultured feline esophageal smooth muscle cells. Arch Pharm Res. 2008 Nov;31(11):1437-45. doi: 10.1007/s12272-001-2128-8. Epub 2008 Nov 2[1]PubMed PMID: 19023540.

[2]Ikeda M, Gunji Y, Sonoda H, Oshikawa S, Shimono M, Horie A, Ito K, Yamasaki S. Inhibitory effect of tyrphostin 47 on Shiga toxin-induced cell death. Eur J Pharmacol. 2006 Sep 28;546(1-3):36-9. Epub 2006 Jul 26. PubMed PMID: 16919262.

[3] Lee TS, Song HJ, Jeong JH, Min YS, Shin CY, Sohn UD. IL-1beta activates p44/42 and p38 mitogen-activated protein kinases via different pathways in cat esophageal smooth muscle cells. World J Gastroenterol. 2006 Feb 7;12(5):716-22. PubMed PMID: 16521184; PubMed Central PMCID: PMC4066121.

[4] Khan SM, Oliver RH, Yeh J. Epidermal growth factor receptor inhibition by tyrphostin 51 induces apoptosis in luteinized granulosa cells. J Clin Endocrinol Metab. 2005 Jan;90(1):469-73. Epub 2004 Oct 19. PubMed PMID: 15494464.

[5] Song HJ, Lee TS, Jeong JH, Min YS, Shin CY, Sohn UD. Hydrogen peroxide-induced extracellular signal-regulated kinase activation in cultured feline ileal smooth muscle cells. J Pharmacol Exp Ther. 2005 Jan;312(1):391-8. Epub 2004 Aug 24. PubMed PMID: 15328380.

6: Chao JC, Peng WL, Chen SH. Effects of epidermal growth factor and its signal transduction inhibitors on apoptosis in human colorectal cancer cells. World J Gastroenterol. 2004 Feb 15;10(4):540-4. PubMed PMID: 14966913; PubMed Central PMCID: PMC4716976.7: Mergler S, Dannowski H, Bednarz J, Engelmann K, Hartmann C, Pleyer U. Calcium influx induced by activation of receptor tyrosine kinases in SV40-transfected human corneal endothelial cells. Exp Eye Res. 2003 Oct;77(4):485-95. PubMed PMID: 12957147.8: Chiang CE, Luk HN, Chen LL, Wang TM, Ding PY. Genistein inhibits the inward rectifying potassium current in guinea pig ventricular myocytes. J Biomed Sci. 2002 Jul-Aug;9(4):321-6. PubMed PMID: 12145529.9: Mergler S, Strauss O. Stimulation of L-type Ca(2+) channels by increase of intracellular InsP3 in rat retinal pigment epithelial cells. Exp Eye Res. 2002 Jan;74(1):29-40. PubMed PMID: 11878816.10: Zeng J, Zheng Q, Zhang W. [Protein tyrosine kinase activation in the repair of rat gastric mucosa after damage]. Zhonghua Yi Xue Za Zhi. 1999 Dec;79(12):934-7. Chinese. PubMed PMID: 11715511.1

对不起，暂无产品评价！

MSDS

SDS 1.0 中文

展开

SDS 1.0 英文

展开