655-05-0|Thozalinone|2-(Dimethylamino)-5-phenyl-1,3-oxazol-4-one|-范德生物科技公司

Thozalinone

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names：
2-(Dimethylamino)-5-phenyl-1,3-oxazol-4-one
CAS号：
655-05-0
MDL Number：
MF(分子式)： C11H12N2O2 MW(分子量)： 204.22
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	2-(Dimethylamino)-5-phenyl-1,3-oxazol-4-one
英文别名	Thozalinone; Tozalinone; Stimsen; CL-39808; CL 39808; CL39808;
CAS号	655-05-0
Inchi	InChI=1S/C11H12N2O2/c1-13(2)11-12-10(14)9(15-11)8-6-4-3-5-7-8/h3-7,9H,1-2H3
InchiKey	JJSHYECKYLDYAR-UHFFFAOYSA-N
分子式 Formula	C11H12N2O2
分子量 Molecular Weight	204.22
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Thozalinone(CAS:655-05-0):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Thozalinone is discontinued (DEA controlled substance). Thozalinone is a psychostimulant agent. It acts by inducing the release of norepinephrine and dopamine.
Application1
Application2
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危险性	Warning
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备注

[1]Yen-Koo HC, Davis DA, Balazs T. Inhibition of dopaminergic agonist-induced gnawing behavior by neuroleptic drugs in mice. Drug Chem Toxicol. 1985;8(6):495-502. PubMed PMID: 2868876.

[2]Gielsdorf W. Determination of the psychostimulants pemoline, fenozolone and thozalinone in human urine by gas chromatography/mass spectrometry and thin layer chromatography. J Clin Chem Clin Biochem. 1982 Feb;20(2):65-8. PubMed PMID: 6121837.

[3] Yen-Koo HC, Balazs T. Detection of dopaminergic supersensitivity induced by neuroleptic drugs in mice. Drug Chem Toxicol. 1980;3(2):237-47. PubMed PMID: 6112126.

[4] Leite AC, Liepen LL, Costa VP. [Clinical trial of Stimsem Thozalinone in the treatment of obese patients]. Rev Bras Med. 1971 Sep;28(9):475-8. Portuguese. PubMed PMID: 5139648.

[5] Berstein BM, Latimer CN. Behavioral facilitation: the interaction of imipramine and desipra- mine with amphetamine, alpha-pipradrol, methylphenidate, and thozalinone. Psychopharmacologia. 1968;12(4):338-45. PubMed PMID: 4385109.

6: Gallant DM, Bishop MP, Scrignar CB, Hornsby L, Moore B, Inturrisi BB. A double-blind study of thozalinone (C1 39,808) in depressed outpatients. Curr Ther Res Clin Exp. 1966 Dec;8(12):621-2. PubMed PMID: 4962734.7: Greenblatt EN, Osterberg AC. Some pharmacologic properties of thozalinone, a new excitant. Toxicol Appl Pharmacol. 1965 Jul;7(4):566-78. PubMed PMID: 4378772.

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