21884-47-9|Rubroskyrin|(8S,8aS,9S,17S,17aR,19R)-1,4,6,8,11,14,19-heptahydroxy-2,12-dimethyl-7,8,8a,9-tetrahydro-9,17-methanonaphtho[2',3'5,6]cyclohepta[1,2-d]anthracene-5,10,15,16,18(17H)-pentaone|-范德生物科技公司

Rubroskyrin

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names：
(8S,8aS,9S,17S,17aR,19R)-1,4,6,8,11,14,19-heptahydroxy-2,12-dimethyl-7,8,8a,9-tetrahydro-9,17-methanonaphtho[2',3'5,6]cyclohepta[1,2-d]anthracene-5,10,15,16,18(17H)-pentaone
CAS号：
21884-47-9
MDL Number：
MF(分子式)： C30H22O12 MW(分子量)： 574.49
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	(8S,8aS,9S,17S,17aR,19R)-1,4,6,8,11,14,19-heptahydroxy-2,12-dimethyl-7,8,8a,9-tetrahydro-9,17-methanonaphtho[2',3'5,6]cyclohepta[1,2-d]anthracene-5,10,15,16,18(17H)-pentaone
英文别名	Rubroskyrin;
CAS号	21884-47-9
Inchi	InChI=1S/C30H22O12/c1-6-3-8(31)12-16(22(6)35)25(38)14-15-19-10(33)5-11(34)20-26(39)13-9(32)4-7(2)23(36)18(13)29(42)30(19,20)21(27(15)40)28(41)17(14)24(12)37/h3-4,10,15,19,21,27,31-36,40H,5H2,1-2H3/t10-,15+,19-,21-,27+,30-/m0/s1
InchiKey	BLXAFSIUPZEETL-TWBHCDLESA-N
分子式 Formula	C30H22O12
分子量 Molecular Weight	574.49
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Rubroskyrin(CAS:21884-47-9):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Rubroskyrin is a modified bis-anthraquinone pigment from Penicillium islandicum Sopp.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Mori S, Kawai K, Nozawa Y, Ogihara Y. The redox reaction and biotransformation of rubroskyrin, a modified bis-anthraquione from Penicillium islandicum Sopp. Nat Toxins. 1998;6(2):85-90. PubMed PMID: 9888634.

[2]KITAGAWA I, SHIBATA S. Metabolic products of fungi. X. The structure of rubroskyrin and its relation to the structure of luteoskyrin. Pharm Bull. 1956 Aug;4(4):309-13. PubMed PMID: 13378957.

[3] Mori S, Kawai K, Nozawa Y, Ogihara Y. The interaction of rubroskyrin, a modified bis-anthraquinone pigment fromPenicillium islandicum Sopp, with respiratory chain of liver mitochondria. Mycotoxin Res. 1997 Mar;13(1):35-42. doi: 10.1007/BF02945060. PubMed PMID: 23604736.

[4] HOWARD BH, RAISTRICK H. Studies in the biochemistry of micro-organisms. 92. The colouring matters of Penicillium islandicum Sopp. 4. Iridoskyrin, rubroskyrin and erythroskyrine. Biochem J. 1954 Jun;57(2):212-22. PubMed PMID: 13172171; PubMed Central PMCID: PMC1269734.

[5] Mori S, Sugihara Y, Kitagawa A, Kawai K, Nozawa Y, Ogihara Y. The respiration-impairing effect of rubroskyrin, a toxic metabolite. Mycotoxin Res. 1996 Sep;12(2):91-8. doi: 10.1007/BF03192267. PubMed PMID: 23604656.

6: Mori H, Yoshimi N, Iwata H, Tanaka T, Kawai K, Sankawa U. Additional survey on genotoxicity of natural anthraquinones in the hepatocyte primary culture/DNA repair assay. J Toxicol Sci. 1988 Aug;13(3):161-6. PubMed PMID: 3193483.7: Stark AA, Townsend JM, Wogan GN, Demain AL, Manmade A, Ghosh AC. Mutagenicity and antibacterial activity of mycotoxins produced by Penicillium islandicum Sopp and Penicillium rugulosum. J Environ Pathol Toxicol. 1978 Nov-Dec;2(2):313-24. PubMed PMID: 368283.8: Ghosh AC, Manmade A, Kobbe B, Townsend JM, Demain AL. Production of luteoskyrin and isolation of a new metabolite, pibasterol, from Penicillium islandicum Sopp. Appl Environ Microbiol. 1978 Mar;35(3):563-6. PubMed PMID: 565188; PubMed Central PMCID: PMC242880.9: Tikkanen L, Matsushima T, Natori S. Mutagenicity of anthraquinones in the Salmonella preincubation test. Mutat Res. 1983 Mar;116(3-4):297-304. PubMed PMID: 6339896.

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