84071-15-8|Ramixotidine|3-((2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)carbamoyl)pyridine 1-oxide|-范德生物科技公司

Ramixotidine

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names：
3-((2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)carbamoyl)pyridine 1-oxide
CAS号：
84071-15-8
MDL Number：
MF(分子式)： C16H21N3O3S MW(分子量)： 335.42
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	3-((2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)carbamoyl)pyridine 1-oxide
英文别名	Ramixotidine;
CAS号	84071-15-8
Inchi	InChI=1S/C16H21N3O3S/c1-18(2)11-14-5-6-15(22-14)12-23-9-7-17-16(20)13-4-3-8-19(21)10-13/h3-6,8,10H,7,9,11-12H2,1-2H3,(H,17,20)
InchiKey	HIVRCMFJEMKPDS-UHFFFAOYSA-N
分子式 Formula	C16H21N3O3S
分子量 Molecular Weight	335.42
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Ramixotidine(CAS:84071-15-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Ramixotidine is a competitive histamine H2-receptor antagonist.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Molgora M, Basilisco G, Bozzani A, Camboni G, Bianchi PA. Intragastric and intraoesophageal pH monitoring in duodenal ulcerpatients: effect of the new histamine H2-receptor antagonist ramixotidine. Eur J Clin Pharmacol. 1989;37(4):405-7. PubMed PMID: 2574675.

[2]Brassinne A, Dresse A, Basilisco G, Manara L. Inhibition of pentagastrin-stimulated gastric acid secretion and plasma levels of the new histamine H2-receptor antagonist ramixotidine dihydrochloride (CM 57755) in human volunteers. Eur J Clin Pharmacol. 1987;32(5):467-70. PubMed PMID: 2957210.

[3] Soldani G, Lavezzo A, Bianchetti A, Manzoni L, Mengozzi G, Manara L. Comparison of the gastric antisecretory effects of ramixotidine dihydrochloride (CM 57755), a new H2 receptor antagonist, and cimetidine in dogs. Pharmacol Res Commun. 1988 Aug;20(8):663-72. PubMed PMID: 2974998.

[4] Colle M, Ruedas E, Cazenave J, Auzerie J, Basilisco G, Camboni G, Manara L. Plasma prolactin, sex steroids and gastrin in human volunteers treated for 2 weeks with therapeutic doses of cimetidine or the new histamine H2-receptor antagonist ramixotidine (CM 57755A). Eur J Clin Pharmacol. 1988;35(5):529-34. PubMed PMID: 2906873.

[5] Lin JH. Pharmacokinetic and pharmacodynamic properties of histamine H2-receptor antagonists. Relationship between intrinsic potency and effective plasma concentrations. Clin Pharmacokinet. 1991 Mar;20(3):218-36. Review. PubMed PMID: 1673880.

6: Wilson JA, Johnston D, Penston J, Wormsley KG. Gastric inhibitory effects of CM57755. A new histamine H2 receptor antagonist. Eur J Clin Pharmacol. 1986;30(1):33-6. PubMed PMID: 2872060.7: Necciari J, Mery D, Garriot P, Escourrou J, Cautreels W. Pharmacokinetics of CM 57755, a new histamine H2-receptor antagonist, after single oral doses in man. Int J Clin Pharmacol Res. 1985;5(6):457-65. PubMed PMID: 2869002.8: Lavezzo A, Manzoni L, Aureggi G, Nisato D, Bianchetti A, Carminati P. In vivo and in vitro effects of CM 57755, a new gastric antisecretory agent acting on histamine H2 receptors. Int J Tissue React. 1984;6(2):155-65. PubMed PMID: 6145676.9: Lavezzo A, Manzoni L, Bianchetti A, Manara L. Inhibition of dimaprit- and pentagastrin-induced gastric acid secretion in cats by the new histamine H2 antagonist, CM 57755. J Pharm Pharmacol. 1986 Nov;38(11):853-6. PubMed PMID: 2879021.

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