78821-76-8|Pneumocysterol|Lanost-8-en-3-ol, 24-ethylidene-, (3beta,24Z)-|-范德生物科技公司

Pneumocysterol

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names：
Lanost-8-en-3-ol, 24-ethylidene-, (3beta,24Z)-
CAS号：
78821-76-8
MDL Number：
MF(分子式)： C32H54O MW(分子量)： 454.783
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Lanost-8-en-3-ol, 24-ethylidene-, (3beta,24Z)-
英文别名	Pneumocysterol
CAS号	78821-76-8
Inchi	InChI=1S/C32H54O/c1-10-23(21(2)3)12-11-22(4)24-15-19-32(9)26-13-14-27-29(5,6)28(33)17-18-30(27,7)25(26)16-20-31(24,32)8/h10,21-22,24,27-28,33H,11-20H2,1-9H3/b23-10-/t22-,24-,27+,28+,30-,31-,32+/m1/s1
InchiKey	XCGCVXQNARNGON-RNBJSANHSA-N
分子式 Formula	C32H54O
分子量 Molecular Weight	454.783
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Pneumocysterol(CAS:78821-76-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Pneumocysterol is a sterol detected in the opportunistic pathogen Pneumocystis carinii hominis.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Kaneshiro ES, Amit Z, Swonger MM, Kreishman GP, Brooks EE, Kreishman M, Jayasimhulu K, Parish EJ, Sun H, Kizito SA, Beach DH. Pneumocysterol [(24Z)-ethylidenelanost-8-en-3beta-ol], a rare sterol detected in the opportunistic pathogen Pneumocystis carinii hominis: structural identity and chemical synthesis. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):97-102. PubMed PMID: 9874778; PubMed Central PMCID: PMC15099.

[2]Kaneshiro ES. Is Pneumocystis a plant? J Eukaryot Microbiol. 2002 Sep-Oct;49(5):367-73. Review. PubMed PMID: 12425523.

[3] Amit Z, Kaneshiro ES. Heterogeneity of Pneumocystis sterol profiles of samples from different sites in the same pair of lungs suggests coinfection by distinct organism populations. J Clin Microbiol. 2001 Mar;39(3):1137-9. PubMed PMID: 11230442; PubMed Central PMCID: PMC87888.

[4] Kaneshiro ES, Wyder MA. C27 to C32 sterols found in Pneumocystis, an opportunistic pathogen of immunocompromised mammals. Lipids. 2000 Mar;35(3):317-24. PubMed PMID: 10783009.

[5] Kaneshiro ES, Amit Z, Chandra J, Baughman RP, Contini C, Lundgren B. Sterols of Pneumocystis carinii hominis organisms isolated from human lungs. Clin Diagn Lab Immunol. 1999 Nov;6(6):970-6. Erratum in: Clin Diagn Lab Immunol 2000 Jan;7(1):129. PubMed PMID: 10548595; PubMed Central PMCID: PMC95807.

6: Kaneshiro ES. Sterol metabolism in the opportunistic pathogen Pneumocystis: advances and new insights. Lipids. 2004 Aug;39(8):753-61. Review. PubMed PMID: 15638243.7: Kaneshiro ES. Pneumocystis carinii pneumonia: the status of Pneumocystis biochemistry. Int J Parasitol. 1998 Jan;28(1):65-84. Review. PubMed PMID: 9504336.8: Kaneshiro ES, Swonger M, Kreishman G, Brooks E, Jayasimhulu K, Parish EJ, Beach DH. Identification of C31 and C32 sterols in Pneumocystis carinii hominis-infected human lungs. J Eukaryot Microbiol. 1996 Sep-Oct;43(5):36S. PubMed PMID: 8822839.9: Kaneshiro ES, Rosenfeld JA, Basselin-Eiweida M, Stringer JR, Keely SP, Smulian AG, Giner JL. The Pneumocystis carinii drug target S-adenosyl-L-methionine:sterol C-24 methyl transferase has a unique substrate preference. Mol Microbiol. 2002 May;44(4):989-99. PubMed PMID: 12010494.10: Giner JL, Zhao H, Amit Z, Kaneshiro ES. Sterol composition of Pneumocystis jirovecii with blocked 14alpha-demethylase activity. J Eukaryot Microbiol. 2004 Nov-Dec;51(6):634-43. PubMed PMID: 15666720.1

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