7635-60-1|Lupinine, (+)-|2H-Quinolizine-1-methanol, octahydro-, (1S-trans)-|-范德生物科技公司

Lupinine, (+)-

NMR下载 COA and HPLC MSDS下载
names：
2H-Quinolizine-1-methanol, octahydro-, (1S-trans)-
CAS号：
7635-60-1
MDL Number：
MF(分子式)： C10H19NO MW(分子量)： 169.268
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Lupinine, (+)-
英文别名	Lupinine, (+)-
CAS号	7635-60-1
Inchi	InChI=1S/C10H19NO/c12-8-9-4-3-7-11-6-2-1-5-10(9)11/h9-10,12H,1-8H2/t9-,10+/m1/s1
InchiKey	HDVAWXXJVMJBAR-ZJUUUORDSA-N
分子式 Formula	C10H19NO
分子量 Molecular Weight	169.268
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Lupinine, (+)-(CAS:7635-60-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Lupinine, (+)- is a bioactive chemical.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Lee JA, An J, Kang TM, De D, Kim KK. Discovery of natural compounds promoting cardiomyocyte differentiation. Stem Cells Dev. 2018 Oct 25. doi: 10.1089/scd.2018.0153. [Epub ahead of print] PubMed PMID: 30358491.

[2]Basilico N, Parapini S, Sparatore A, Romeo S, Misiano P, Vivas L, Yardley V, Croft SL, Habluetzel A, Lucantoni L, Renia L, Russell B, Suwanarusk R, Nosten F, Dondio G, Bigogno C, Jabes D, Taramelli D. In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial. Molecules. 2017 Dec 1;22(12). pii: E2102. doi: 10.3390/molecules22122102. PubMed PMID: 29194347.

[3] Davies SG, Fletcher AM, Foster EM, Houlsby IT, Roberts PM, Schofield TM, Thomson JE. The asymmetric syntheses of pyrrolizidines, indolizidines and quinolizidines via two sequential tandem ring-closure/N-debenzylation processes. Org Biomol Chem. 2014 Dec 7;12(45):9223-35. doi: 10.1039/c4ob01737d. PubMed PMID: 25300749.

[4] Koley D, Krishna Y, Srinivas K, Khan AA, Kant R. Organocatalytic asymmetric Mannich cyclization of hydroxylactams with acetals: total syntheses of (-)-epilupinine, (-)-tashiromine, and (-)-trachelanthamidine. Angew Chem Int Ed Engl. 2014 Nov 24;53(48):13196-200. doi: 10.1002/anie.201407185. Epub 2014 Sep 26. PubMed PMID: 25264221.

[5] Davies SG, Fletcher AM, Foster EM, Houlsby IT, Roberts PM, Schofield TM, Thomson JE. An efficient asymmetric synthesis of (-)-lupinine. Chem Commun (Camb). 2014 Aug 7;50(61):8309-11. doi: 10.1039/c4cc02135e. PubMed PMID: 24938152.

6: Brimioulle R, Bach T. Enantioselective Lewis acid catalysis of intramolecular enone [2+2] photocycloaddition reactions. Science. 2013 Nov 15;342(6160):840-3. doi: 10.1126/science.1244809. PubMed PMID: 24233720.7: Jahn MK, Dewald D, Vallejo-López M, Cocinero EJ, Lesarri A, Grabow JU. Rotational spectra of bicyclic decanes: the trans conformation of (-)-lupinine. J Phys Chem A. 2013 Dec 19;117(50):13673-9. doi: 10.1021/jp407671m. Epub 2013 Sep 27. PubMed PMID: 24028578.8: Rusconi C, Vaiana N, Casagrande M, Basilico N, Parapini S, Taramelli D, Romeo S, Sparatore A. Synthesis and comparison of antiplasmodial activity of (+), (-) and racemic 7-chloro-4-(N-lupinyl)aminoquinoline. Bioorg Med Chem. 2012 Oct 1;20(19):5980-5. doi: 10.1016/j.bmc.2012.07.041. Epub 2012 Jul 31. PubMed PMID: 22901673.9: Basova NE, Kormilitsyn BN, Perchenok AIu, Rozengart EV, Saakov VS, Suvorov AA. [Reversible lupininin inhibitors of cholinesterases of mammalian blood and of optical ganglia of individuals of the commander squid Berryteuthis magister from different zones of species areal]. Zh Evol Biokhim Fiziol. 2012 May-Jun;48(3):213-8. Russian. PubMed PMID: 22827020.10: Basova NE, Kormilitsyn BN, Perchenok AIu, Rosengart EV, Saakov VS, Suvorov AA. [Isomeric derivatives of lupinine and epilupinine--organophosphorus inhibitors of cholinesterases]. Ukr Biokhim Zh (1999). 2012 Jan-Feb;84(1):26-33. Russian. PubMed PMID: 22679755.1

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