126062-18-8|Lobucavir|2-Amino-9-(2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro-6H-purin-6-one|-范德生物科技公司

Lobucavir

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names：
2-Amino-9-(2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro-6H-purin-6-one
CAS号：
126062-18-8
MDL Number：
MF(分子式)： C11H15N5O3 MW(分子量)： 265.273
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Lobucavir
英文别名	Lobucavir; Cyclobut-G
CAS号	126062-18-8
Inchi	InChI=1S/C11H15N5O3/c12-11-14-9-8(10(19)15-11)13-4-16(9)7-1-5(2-17)6(7)3-18/h4-7,17-18H,1-3H2,(H3,12,14,15,19)
InchiKey	GWFOVSGRNGAGDL-UHFFFAOYSA-N
分子式 Formula	C11H15N5O3
分子量 Molecular Weight	265.273
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Lobucavir(CAS:126062-18-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Lobucavir, also known as Cyclobut-G, inhibits the replication of HIV virus in T cells, monocytes & macrophages in vitro by inhibiting DNA polymerase and viral DNA synthesis.
Application1
Application2
Application3

警示图
危险性	Warning
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备注

[1]De Clercq E, Naesens L, De Bolle L, Schols D, Zhang Y, Neyts J. Antiviral agents active against human herpesviruses HHV-6, HHV-7 and HHV-8. Rev Med Virol. 2001 Nov-Dec;11(6):381-95. Review. PubMed PMID: 11747000.

[2]Alrabiah FA, Sacks SL. New antiherpesvirus agents. Their targets and therapeutic potential. Drugs. 1996 Jul;52(1):17-32. Review. PubMed PMID: 8799682.

[3] Christensen ND, Pickel MD, Budgeon LR, Kreider JW. In vivo anti-papillomavirus activity of nucleoside analogues including cidofovir on CRPV-induced rabbit papillomas. Antiviral Res. 2000 Nov;48(2):131-42. PubMed PMID: 11114415.

[4] Hoffman VF, Skiest DJ. Therapeutic developments in cytomegalovirus retinitis. Expert Opin Investig Drugs. 2000 Feb;9(2):207-20. Review. PubMed PMID: 11060672.

[5] Hebart H, Kanz L, Jahn G, Einsele H. Management of cytomegalovirus infection after solid-organ or stem-cell transplantation. Current guidelines and future prospects. Drugs. 1998 Jan;55(1):59-72. Review. PubMed PMID: 9463790.

6: Marques AR, Straus SE. Advances in the treatment of chronic hepatitis B virus infection. Rev Med Virol. 1998 Oct;8(4):223-234. PubMed PMID: 10398511.7: Field AK, Tuomari AV, McGeever-Rubin B, Terry BJ, Mazina KE, Haffey ML, Hagen ME, Clark JM, Braitman A, Slusarchyk WA, et al. (+-)-(1 alpha,2 beta,3 alpha)-9-[2,3-bis(hydroxymethyl)-cyclobutyl] guanine [(+-)-BHCG or SQ 33,054]: a potent and selective inhibitor of herpesviruses. Antiviral Res. 1990 Jan;13(1):41-52. PubMed PMID: 2159261.8: Yang H, Drain RL, Franco CA, Clark JM. Efficacy of BMS-180194 against experimental cytomegalovirus infections in immunocompromised mice. Antiviral Res. 1996 Mar;29(2-3):233-41. PubMed PMID: 8739602.9: Hu N, Shiota H. Emergence of resistance to carbocyclic oxetanocin G in herpes simplex virus type 1 and genetic analysis of resistant mutants. Acta Pharmacol Sin. 2004 Jul;25(7):921-6. PubMed PMID: 15210066.10: Ying C, De Clercq E, Nicholson W, Furman P, Neyts J. Inhibition of the replication of the DNA polymerase M550V mutation variant of human hepatitis B virus by adefovir, tenofovir, L-FMAU, DAPD, penciclovir and lobucavir. J Viral Hepat. 2000 Mar;7(2):161-5. PubMed PMID: 10760047.1

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