82570-34-1|Lemnalol|(1R,2S,4R,6S,7R,8S)-8-isopropyl-1-methyl-3-methylenetricyclo[4.4.0.02,7]decan-4-ol|-范德生物科技公司

Lemnalol

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names：
(1R,2S,4R,6S,7R,8S)-8-isopropyl-1-methyl-3-methylenetricyclo[4.4.0.02,7]decan-4-ol
CAS号：
82570-34-1
MDL Number：
MF(分子式)： C15H24O MW(分子量)： 220.35
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Lemnalol
英文别名	Lemnalol;
CAS号	82570-34-1
Inchi	InChI=1S/C15H24O/c1-8(2)10-5-6-15(4)11-7-12(16)9(3)14(15)13(10)11/h8,10-14,16H,3,5-7H2,1-2,4H3/t10-,11-,12+,13+,14-,15+/m0/s1
InchiKey	LPXOPRGPLUWGKB-JRULLXGZSA-N
分子式 Formula	C15H24O
分子量 Molecular Weight	220.35
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Lemnalol(CAS:82570-34-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Lemnalol is a natural marine compound isolated from the Formosan soft coral Lemnalia cervicorni. Lemnalol produced anti-inflammatory and analgesic effects in carrageenan-injected rats.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Lee HP, Lin YY, Duh CY, Huang SY, Wang HM, Wu SF, Lin SC, Jean YH, Wen ZH. Lemnalol attenuates mast cell activation and osteoclast activity in a gouty arthritis model. J Pharm Pharmacol. 2015 Feb;67(2):274-85. doi: 10.1111/jphp.1233[1]Epub 2014 Dec 3[1]PubMed PMID: 25557511.

[2]Lee HP, Huang SY, Lin YY, Wang HM, Jean YH, Wu SF, Duh CY, Wen ZH. Soft coral-derived lemnalol alleviates monosodium urate-induced gouty arthritis in rats by inhibiting leukocyte infiltration and iNOS, COX-2 and c-Fos protein expression. Mar Drugs. 2013 Jan 10;11(1):99-113. doi: 10.3390/md11010099. PubMed PMID: 23306170; PubMed Central PMCID: PMC3564160.

[3] Lin YC, Huang SY, Jean YH, Chen WF, Sung CS, Kao ES, Wang HM, Chakraborty C, Duh CY, Wen ZH. Intrathecal lemnalol, a natural marine compound obtained from Formosan soft coral, attenuates nociceptive responses and the activity of spinal glial cells in neuropathic rats. Behav Pharmacol. 2011 Dec;22(8):739-50. doi: 10.1097/FBP.0b013e32834d0ecb. PubMed PMID: 22067479.

[4] Jean YH, Chen WF, Duh CY, Huang SY, Hsu CH, Lin CS, Sung CS, Chen IM, Wen ZH. Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory and analgesic effects of the natural marine compound lemnalol from Formosan soft coral Lemnalia cervicorni. Eur J Pharmacol. 2008 Jan 14;578(2-3):323-31. Epub 2007 Sep 20. PubMed PMID: 17916350.

[5] Kikuchi H, Manda T, Kobayashi K, Yamada Y, Iguchi K. Anti-tumor activity of lemnalol isolated from the soft coral Lemnalia tenuis Verseveldt. Chem Pharm Bull (Tokyo). 1983 Mar;31(3):1086-8. PubMed PMID: 6136342.

6: Cheng SY, Lin EH, Huang JS, Wen ZH, Duh CY. Ylangene-type and nardosinane-type sesquiterpenoids from the soft corals Lemnalia flava and Paralemnalia thyrsoides. Chem Pharm Bull (Tokyo). 2010 Mar;58(3):381-5. PubMed PMID: 20190445.7: Duh CY, El-Gamal AA, Song PY, Wang SK, Dai CF. Steroids and sesquiterpenoids from the soft corals Dendronephthya gigantea and Lemnalia cervicorni. J Nat Prod. 2004 Oct;67(10):1650-3. PubMed PMID: 15497934.

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