76433-29-9|Lds 751|2-((1E,3E)-4-(4-(dimethylamino)phenyl)buta-1,3-dien-1-yl)-3-ethylbenzo[d]thiazol-3-ium perchlorate|-范德生物科技公司

Lds 751

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names：
2-((1E,3E)-4-(4-(dimethylamino)phenyl)buta-1,3-dien-1-yl)-3-ethylbenzo[d]thiazol-3-ium perchlorate
CAS号：
76433-29-9
MDL Number：
MF(分子式)： C21H23ClN2O4S MW(分子量)： 434.93
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Lds 751
英文别名	Lds 751; Lds-751; Lds751; Exciton;
CAS号	76433-29-9
Inchi	InChI=1S/C21H23N2S.ClHO4/c1-4-23-19-10-6-7-11-20(19)24-21(23)12-8-5-9-17-13-15-18(16-14-17)22(2)3;2-1(3,4)5/h5-16H,4H2,1-3H3;(H,2,3,4,5)/q+1;/p-1
InchiKey	FWTLKTVVDHEQMM-UHFFFAOYSA-M
分子式 Formula	C21H23ClN2O4S
分子量 Molecular Weight	434.93
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Lds 751(CAS:76433-29-9):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Lds 751 is a nucleic acid stain; preferentially stains nucleated cells.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Snyder DS, Small PL. Staining of cellular mitochondria with LDS-75[1]J Immunol Methods. 2001 Nov 1;257(1-2):35-40. PubMed PMID: 11687236.

[2]Lugo MR, Sharom FJ. Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs. Biochemistry. 2005 Oct 25;44(42):14020-9. PubMed PMID: 16229491.

[3] Lugo MR, Sharom FJ. Interaction of LDS-751 with the drug-binding site of P-glycoprotein: a Trp fluorescence steady-state and lifetime study. Arch Biochem Biophys. 2009 Dec;492(1-2):17-28. doi: 10.1016/j.abb.2009.10.002. Epub 2009 Oct 8. PubMed PMID: 19818729.

[4] Shapiro AB, Ling V. Transport of LDS-751 from the cytoplasmic leaflet of the plasma membrane by the rhodamine-123-selective site of P-glycoprotein. Eur J Biochem. 1998 May 15;254(1):181-8. PubMed PMID: 9652412.

[5] Lugo MR, Sharom FJ. Interaction of LDS-751 with P-glycoprotein and mapping of the location of the R drug binding site. Biochemistry. 2005 Jan 18;44(2):643-55. PubMed PMID: 15641790.

6: Maes ML, Davidson LB, McDonagh PF, Ritter LS. Comparison of sample fixation and the use of LDS-751 or anti-CD45 for leukocyte identification in mouse whole blood for flow cytometry. J Immunol Methods. 2007 Jan 30;319(1-2):79-86. Epub 2006 Dec 8. PubMed PMID: 17187818; PubMed Central PMCID: PMC1896319.7: Terstappen LW, Shah VO, Conrad MP, Recktenwald D, Loken MR. Discriminating between damaged and intact cells in fixed flow cytometric samples. Cytometry. 1988 Sep;9(5):477-84. PubMed PMID: 2460298.8: Clay AT, Sharom FJ. Lipid bilayer properties control membrane partitioning, binding, and transport of p-glycoprotein substrates. Biochemistry. 2013 Jan 15;52(2):343-54. doi: 10.1021/bi301532c. Epub 2013 Jan 4. PubMed PMID: 23268645.9: Neukirch AJ, Neumark DM, Kling MF, Prezhdo OV. Resolving multi-exciton generation by attosecond spectroscopy. Opt Express. 2014 Oct 20;22(21):26285-93. doi: 10.1364/OE.22.026285. PubMed PMID: 25401661.10: Xue P, Yao B, Wang P, Gong P, Zhang Z, Lu R. Strong Fluorescent Smart Organogel as a Dual Sensing Material for Volatile Acid and Organic Amine Vapors. Chemistry. 2015 Nov 23;21(48):17508-15. doi: 10.1002/chem.201502401. Epub 2015 Oct 9. PubMed PMID: 26449736.1

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