363-36-0|Kynuramine|1-Propanone, 3-amino-1-(2-aminophenyl)-|-范德生物科技公司

Kynuramine

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names：
1-Propanone, 3-amino-1-(2-aminophenyl)-
CAS号：
363-36-0
MDL Number：
MF(分子式)： C9H12N2O MW(分子量)： 164.21
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Kynuramine
英文别名	Kynuramine;
CAS号	363-36-0
Inchi	InChI=1S/C9H12N2O/c10-6-5-9(12)7-3-1-2-4-8(7)11/h1-4H,5-6,10-11H2
InchiKey	QLPVTIQQFGWSQQ-UHFFFAOYSA-N
分子式 Formula	C9H12N2O
分子量 Molecular Weight	164.21
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Kynuramine(CAS:363-36-0):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Kynuramine is an aromatic ketone containing the aniline structure.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Niu S, Li F, Tan DX, Zhang L, Idle JR, Gonzalez FJ, Ma X. Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in mice. J Pineal Res. 2010 Sep;49(2):106-14. doi: 10.1111/j.1600-079X.2010.00771.x. Epub 2010 May 27. PubMed PMID: 20545825; PubMed Central PMCID: PMC4699585.

[2]Pomfret DW, Schenck KW, Fludzinski P, Cohen ML. Interaction of 5-hydroxykynurenamine, L-kynurenine and kynuramine with multiple serotonin receptors in smooth muscle. J Pharmacol Exp Ther. 1987 May;241(2):465-71. PubMed PMID: 3572806.

[3] Charlton KG, Johnson TD, Hamed AT, Clarke DE. Cardiovascular actions of kynuramine and 5-hydroxykynuramine in pithed rats. J Neural Transm. 1983;57(4):199-211. PubMed PMID: 6140297.

[4] Johnson TD, Clarke DE. An alpha-adrenoceptor inhibitory action of kynuramine. Eur J Pharmacol. 1981 Jul 10;72(4):351-6. PubMed PMID: 6115758.

[5] Johnson TD, Clarke DE. Blood pressure and heart rate effects of kynuramine in pithed rats. Eur J Pharmacol. 1983 Feb 18;87(2-3):323-6. PubMed PMID: 6132830.

6: Matsumoto T, Suzuki O, Furuta T, Asai M, Kurokawa Y, Nimura Y, Katsumata Y, Takahashi I. A sensitive fluorometric assay for serum monoamine oxidase with kynuramine as substrate. Clin Biochem. 1985 Apr;18(2):126-9. PubMed PMID: 4017223.7: Mendelson SD, Lee N, Gorzalka BB. Intraventricular administration of l-kynurenine and kynuramine facilitates lordosis in the female rat. Eur J Pharmacol. 1987 Oct 27;142(3):447-51. PubMed PMID: 3428356.8: Johnson TD, Charlton KG, Clarke DE. Cardiac norepinephrine releasing action of kynuramine, an endogenous diamine derived from L-tryptophan. Life Sci. 1984 Dec 3;35(23):2303-10. PubMed PMID: 6503615.9: Massey JB, Churchich JE. Kynuramine, a fluorescent substrate and probe of plasma amine oxidase. J Biol Chem. 1977 Nov 25;252(22):8081-4. PubMed PMID: 562342.10: Chayah M, Carrión MD, Gallo MA, Jiménez R, Duarte J, Camacho ME. Development of urea and thiourea kynurenamine derivatives: synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors. ChemMedChem. 2015 May;10(5):874-82. doi: 10.1002/cmdc.201500007. Epub 2015 Mar 20. PubMed PMID: 25801086.1

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