129966-45-6|Kapurimycin A3|2H-Pyran-2-acetic acid, alpha-ethyl-6-(1-ethyl-4-(2,3,3a,4,5,7a-hexahydro-4-(1H-pyrrol-2-ylcarbonyl)-1H-inden-5-yl)-1,3-butadienyl)tetrahydro-5-methyl-, (3aR-(3aalpha,4alpha,5alpha(1E(2R*(R*),5S*,6R*),3E),7abeta))-|-范德生物科技公司

Kapurimycin A3

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names：
2H-Pyran-2-acetic acid, alpha-ethyl-6-(1-ethyl-4-(2,3,3a,4,5,7a-hexahydro-4-(1H-pyrrol-2-ylcarbonyl)-1H-inden-5-yl)-1,3-butadienyl)tetrahydro-5-methyl-, (3aR-(3aalpha,4alpha,5alpha(1E(2R*(R*),5S*,6R*),3E),7abeta))-
CAS号：
129966-45-6
MDL Number：
MF(分子式)： C30H41NO4 MW(分子量)： 479.66
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Kapurimycin A3
英文别名	Caphamycin; Kafamycin; Kaphamycin;
CAS号	129966-45-6
Inchi	InChI=1S/C30H41NO4/c1-4-20(29-19(3)14-17-26(35-29)23(5-2)30(33)34)9-6-11-22-16-15-21-10-7-12-24(21)27(22)28(32)25-13-8-18-31-25/h6,8-9,11,13,15-16,18-19,21-24,26-27,29,31H,4-5,7,10,12,14,17H2,1-3H3,(H,33,34)/b11-6+,20-9+/t19-,21-,22?,23?,24+,26+,27+,29+/m0/s1
InchiKey	XINFXFISYDXMAU-WIXGUGHWSA-N
分子式 Formula	C30H41NO4
分子量 Molecular Weight	479.66
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Kapurimycin A3(CAS:129966-45-6):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Kapurimycin A3 is an antitumour antibiotic.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Sugiyama H, Lam CK, Hosoda M, Saito I. Site specific covalent alkylation of DNA by antitumor antibiotics, duocarmycin A and kapurimycin A3. Nucleic Acids Symp Ser. 1991;(25):75-6. PubMed PMID: 1842103.

[2]Hara M, Yoshida M, Nakano H. Covalent modification and single-strand scission of DNA by a new antitumor antibiotic kapurimycin A3. Biochemistry. 1990 Nov 20;29(46):10449-55. PubMed PMID: 2271655.

[3] Chan KL, Sugiyama H, Saito I, Hara M. NMR characterization of guanine DNA site alkylated by kapurimycin A3, an antitumour antibiotic from Streptomyces sp. Phytochemistry. 1995 Nov;40(5):1373-4. PubMed PMID: 8534399.

[4] Okamoto A, Nakatani K, Saito I. Studies on the mechanism of DNA sequence selective alkylation by kapurimycin A3 analogs. Nucleic Acids Symp Ser. 1997;(37):27-8. PubMed PMID: 9585982.

[5] Saito I. Chemistry of drug-induced DNA lesions. Toxicol Lett. 1993 Apr;67(1-3):3-15. PubMed PMID: 8451767.

6: Hara M, Mokudai T, Kobayashi E, Gomi K, Nakano H. The kapurimycins, new antitumor antibiotics produced by Streptomyces. Producing organism, fermentation, isolation and biological activities. J Antibiot (Tokyo). 1990 Dec;43(12):1513-8. PubMed PMID: 2276970.7: Yoshida M, Hara M, Saitoh Y, Sano H. The kapurimycins, new antitumor antibiotics produced by Streptomyces. Physico-chemical properties and structure determination. J Antibiot (Tokyo). 1990 Dec;43(12):1519-23. PubMed PMID: 2276971.

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