12706-94-4|Hikizimycin|4-amino-1-[5-amino-6-[1-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6-pentahydroxyhexyl]-3,4-dihydroxyoxan-2-yl]pyrimidin-2-one|-范德生物科技公司

Hikizimycin

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names：
4-amino-1-[5-amino-6-[1-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6-pentahydroxyhexyl]-3,4-dihydroxyoxan-2-yl]pyrimidin-2-one
CAS号：
12706-94-4
MDL Number：
MF(分子式)： C21H37N5O14 MW(分子量)： 583.548
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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FMK16060-100mg	100mg	>98%	¥ 0.00	¥ 0.00		Get quote	- +	¥ 0.00

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中文别名	Hikizimycin
英文别名	Hikizimycin; Anthelmycin; L 33876
CAS号	12706-94-4
Inchi	InChI=1S/C21H37N5O14/c22-7-1-2-26(21(37)25-7)19-16(36)12(32)9(24)17(39-19)18(15(35)14(34)10(30)5(29)3-27)40-20-13(33)8(23)11(31)6(4-28)38-20/h1-2,5-6,8-20,27-36H,3-4,23-24H2,(H2,22,25,37)
InchiKey	VQQSDVBOXQHCHU-UHFFFAOYSA-N
分子式 Formula	C21H37N5O14
分子量 Molecular Weight	583.548
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Hikizimycin(CAS:12706-94-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Hikizimycin is an antibiotic with antihelmintic properties.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]González A, Vázquez D, Jiménez A. Inhibition of translation in bacterial and eukaryotic systems by the antibiotic anthelmycin (hikizimycin). Biochim Biophys Acta. 1979 Feb 27;561(2):403-9. PubMed PMID: 371683.

[2]Lacal JC, Vázquez D, Fernandez-Sousa JM, Carrasco L. Antibiotics that specifically block translation in virus-infected cells. J Antibiot (Tokyo). 1980 Apr;33(4):441-6. PubMed PMID: 6251018.

[3] Rodriguez-Fonseca C, Amils R, Garrett RA. Fine structure of the peptidyl transferase centre on 23 S-like rRNAs deduced from chemical probing of antibiotic-ribosome complexes. J Mol Biol. 1995 Mar 24;247(2):224-35. PubMed PMID: 7707371.

[4] Fürstner A, Wuchrer M. Concise approach to the "higher sugar" core of the nucleoside antibiotic hikizimycin. Chemistry. 2005 Dec 16;12(1):76-89. PubMed PMID: 16196060.

[5] Vuilhorgne M, Ennifar S, Das BC, Paschal JW, Nagarajan R, Hagaman EW, Wenkert E. Structure analysis of the nucleoside disaccharide antibiotic anthelmycin by carbon-13 nuclear magnetic resonance spectroscopy. A structural revision of hikizimycin and its identity with anthelmycin. J Org Chem. 1977 Sep 30;42(20):3289-91. PubMed PMID: 903851.

6: Fernández-Puentes C. Permeability to inhibitors of protein synthesis in virus infected cells. Mol Biol Rep. 1984 Dec;10(2):65-8. PubMed PMID: 6527684.7: Uchida K, Ichikawa T, Shimauchi Y, Ishikura T, Ozaki A. Hikizimycin, a new antibiotic. J Antibiot (Tokyo). 1971 Apr;24(4):259-62. PubMed PMID: 5572754.8: Uchida K, Das BC. Hikosamine, a novel C11 aminosugar component of the antibiotic hikizimycin. Biochimie. 1973 May;55(5):635-6. PubMed PMID: 4754193.9: Das BC, Defaye J, Uchida K. The structure of hikizimycin. I. Identification of 3-amino-3-deoxy-D-glucose and cytosine as structural components. Carbohydr Res. 1972 May;22(2):293-9. PubMed PMID: 5047747.10: HAMMILL RL, HOEHN M. ANTHELMYCIN, A NEW ANTIBIOTIC WITH ANTHELMINTIC PROPERTIES. J Antibiot (Tokyo). 1964 May;17:100-3. PubMed PMID: 14171214.1

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