21618-99-5|H77-77|5-(2-Aminopropyl)-2-methylphenol|-范德生物科技公司

H77-77

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names：
5-(2-Aminopropyl)-2-methylphenol
CAS号：
21618-99-5
MDL Number：
MF(分子式)： C10H15NO MW(分子量)： 165.236
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	H77-77
英文别名	H77-77; H77 77; H7777; H77/77
CAS号	21618-99-5
Inchi	InChI=1S/C10H15NO/c1-7-3-4-9(5-8(2)11)6-10(7)12/h3-4,6,8,12H,5,11H2,1-2H3
InchiKey	XWLXNPMITZDCHL-UHFFFAOYSA-N
分子式 Formula	C10H15NO
分子量 Molecular Weight	165.236
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	H77-77(CAS:21618-99-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	H77-77 is a monoamine oxidase (MAO) inhibitor. In rats, H77-77 produces a pronounced protection against phenelzine within the serotonergic and noradrenergic neurons.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Fagervall I, Kelder D, Ross SB. Selective inhibition by 4,alpha-dimethyl-m-tyramine (H77/77) and 4-methyl-alpha-ethyl-m-tyramine (H75/12) of the monoamine oxidase within serotonergic and noradrenergic neurons in the rat brain. Naunyn Schmiedebergs Arch Pharmacol. 1988 Aug;338(2):143-7. PubMed PMID: 2460774.

[2]Fuxe K, Janson AM, Rosén L, Finnman UB, Tanganelli S, Morari M, Goldstein M, Agnati LF. Evidence for a protective action of the vigilance promoting drug modafinil on the MPTP-induced degeneration of the nigrostriatal dopamine neurons in the black mouse: an immunocytochemical and biochemical analysis. Exp Brain Res. 1992;88(1):117-30. PubMed PMID: 1347270.

[3] Leonard BE, Shallice SA. Some neurochemical effects of amphetamine, methylamphetamine and p-bromomethylamphetamine in the rat. Br J Pharmacol. 1971 Feb;41(2):198-212. PubMed PMID: 5572273; PubMed Central PMCID: PMC1703283.

[4] Maj J, Melzacka M, Mogilnicka E, Daniel W. Different pharmacokinetic and pharmacological effects following acute and chronic treatment with imipramine. J Neural Transm. 1982;54(3-4):219-28. PubMed PMID: 7130974.

[5] Lotti VJ, Clineschmidt BV, Haubrich D, Porter CC. 6-Chloro-2(1-piperazinyl) quinoxaline (CPQ): action on serotonin-induced behavioral responses and interactions with chloromethamphetamine and dimethyl-meta-tyramine. Arch Int Pharmacodyn Ther. 1978 Sep;235(1):103-15. PubMed PMID: 153735.

6: Moret C, Charveron M, Finberg JP, Couzinier JP, Briley M. Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug. Neuropharmacology. 1985 Dec;24(12):1211-9. PubMed PMID: 3005901.

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