512-17-4|Farnesiferol C|7-[(E)-3-Methyl-5-[(1R,3R,4S)-2,2,4-trimethyl-7-oxabicyclo[2.2.1]heptan-3-yl]pent-2-enoxy]chromen-2-one|-范德生物科技公司

Farnesiferol C

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names：
7-[(E)-3-Methyl-5-[(1R,3R,4S)-2,2,4-trimethyl-7-oxabicyclo[2.2.1]heptan-3-yl]pent-2-enoxy]chromen-2-one
CAS号：
512-17-4
MDL Number：
MF(分子式)： C24H30O4 MW(分子量)： 382.5
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Farnesiferol C
英文别名	Farnesiferol C; Farnesiferol-C;
CAS号	512-17-4
Inchi	InChI=1S/C24H30O4/c1-16(5-9-20-23(2,3)21-11-13-24(20,4)28-21)12-14-26-18-8-6-17-7-10-22(25)27-19(17)15-18/h6-8,10,12,15,20-21H,5,9,11,13-14H2,1-4H3/b16-12+/t20-,21-,24+/m1/s1
InchiKey	OCHZHKVSLMBEJP-QYQYHAIPSA-N
分子式 Formula	C24H30O4
分子量 Molecular Weight	382.5
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Farnesiferol C(CAS:512-17-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Farnesiferol C induces apoptosis via regulation of L11 and c-Myc. Farnesiferol C has combinational potential with anticancer drugs in non-small-cell lung cancers.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Aldaghi L, Rad A, Arab A, Kasaian J, Iranshahi M, Sadr AS, Soltani F. In Silico and In Vitro Evaluation of Cytotoxic Activities of Farnesiferol C and Microlobin on MCF-7, HeLa and KYSE Cell Lines. Drug Res (Stuttg). 2016 Oct;66(10):532-538. Epub 2016 Jul 27. PubMed PMID: 27463028.

[2]Jung JH, Kim MJ, Lee H, Lee J, Kim J, Lee HJ, Shin EA, Kim YH, Kim B, Shim BS, Kim SH. Farnesiferol c induces apoptosis via regulation of L11 and c-Myc with combinational potential with anticancer drugs in non-small-cell lung cancers. Sci Rep. 2016 May 27;

6:26844. doi: 10.1038/srep26844. PubMed PMID: 27231235; PubMed Central PMCID: PMC4882547.

[4]Kasaian J, Mosaffa F, Behravan J, Masullo M, Piacente S, Iranshahi M. Modulation of Multidrug Resistance Protein 2 Efflux in the Cisplatin Resistance Human Ovarian Carcinoma Cells A2780/RCIS by Sesquiterpene Coumarins. Phytother Res. 2016 Jan;30(1):84-9. doi: 10.1002/ptr.5504. Epub 2015 Oct 27. PubMed PMID: 26503061.

[5] Aas Z, Babaei E, Hosseinpour Feizi MA, Dehghan G. Anti-proliferative and Apoptotic Effects of Dendrosomal Farnesiferol C on Gastric Cancer Cells. Asian Pac J Cancer Prev. 2015;16(13):5325-9. PubMed PMID: 26225673.

5: Kasaian J, Mosaffa F, Behravan J, Masullo M, Piacente S, Ghandadi M, Iranshahi M. Reversal of P-glycoprotein-mediated multidrug resistance in MCF-7/Adr cancer cells by sesquiterpene coumarins. Fitoterapia. 2015 Jun;10

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