67-98-1|Ethamoxytriphetol|Benzeneethanol, alpha-(4-(2-(diethylamino)ethoxy)phenyl)-4-methoxy-alpha-phenyl-|-范德生物科技公司

Ethamoxytriphetol

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names：
Benzeneethanol, alpha-(4-(2-(diethylamino)ethoxy)phenyl)-4-methoxy-alpha-phenyl-
CAS号：
67-98-1
MDL Number：
MF(分子式)： C27H33NO3 MW(分子量)： 419.57
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Ethamoxytriphetol
英文别名	Ethamoxytriphetol
CAS号	67-98-1
Inchi	InChI=1S/C27H33NO3/c1-4-28(5-2)19-20-31-26-17-13-24(14-18-26)27(29,23-9-7-6-8-10-23)21-22-11-15-25(30-3)16-12-22/h6-18,29H,4-5,19-21H2,1-3H3
InchiKey	KDYQVUUCWUPJGE-UHFFFAOYSA-N
分子式 Formula	C27H33NO3
分子量 Molecular Weight	419.57
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Ethamoxytriphetol(CAS:67-98-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Ethamoxytriphetol is a non-steroidal estrogen antagonist.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Craig Jordan V, McDaniel R, Agboke F, Maximov PY. The evolution of nonsteroidal antiestrogens to become selective estrogen receptor modulators. Steroids. 2014 Nov;90:3-12. doi: 10.1016/j.steroids.2014.06.009. Epub 2014 Jun 17. PubMed PMID: 24949934; PubMed Central PMCID: PMC4192084.

[2]Dobrydneva Y, Weatherman RV, Trebley JP, Morrell MM, Fitzgerald MC, Fichandler CE, Chatterjie N, Blackmore PF. Tamoxifen stimulates calcium entry into human platelets. J Cardiovasc Pharmacol. 2007 Oct;50(4):380-90. PubMed PMID: 18049305.

[3] Weems YS, Lewis AW, Randel RD, Weems CW. Effects of prostaglandins E2 and F2alpha (PGE2; PGF2alpha), trilostane, mifepristone, palmitic acid (PA), indomethacin (INDO), ethamoxytriphetol (MER-25), PGE2 + PA, or PGF2alpha + PA on PGE2, PGF2alpha, and progesterone secretion by bovine corpora lutea of mid-pregnancy in vitro. Chin J Physiol. 2002 Dec 31;45(4):163-8. Erratum in: Chin J Physiol. 2003 Mar 31;46(1):40. PubMed PMID: 12817707.

[4] Kim L, Weems YS, Bridges PJ, LeaMaster BR, Ching L, Vincent DL, Weems CW. Effects of indomethacin, luteinizing hormone (LH), prostaglandin E2 (PGE2), trilostane, mifepristone, ethamoxytriphetol (MER-25) on secretion of prostaglandin E (PGE), prostaglandin F2alpha (PGF2alpha) and progesterone by ovine corpora lutea of pregnancy or the estrous cycle. Prostaglandins Other Lipid Mediat. 2001 Mar;63(4):189-203. PubMed PMID: 11305696.

[5] Hossain MB, van der Helm D, Schmitz FJ, Pordesimo EO, Magarian RA, Meyer KL, Overacre LB, Day BW. Molecular structures and conformational studies of triarylcyclopropyl and related nonsteroidal antiestrogens. J Med Chem. 1994 May 27;37(11):1670-83. PubMed PMID: 8201601.

6: Ganesan R. The aversive and hypophagic effects of estradiol. Physiol Behav. 1994 Feb;55(2):279-85. PubMed PMID: 8153166.7: Pepe GJ, Waddell BJ, Sinosich MJ, Albrecht ED. Influence of fetectomy on serum pregnancy-associated plasma protein-A concentrations in the baboon. Biol Reprod. 1994 Feb;50(2):442-8. PubMed PMID: 7511420.8: Hossain MB, Symersky J, Neely SC, van der Helm D, Magarian RA. Structure of 1-(4-[2-(diethylamino)ethoxy]phenyl)-2-(4-methoxyphenyl)-1-phenylethan- 1-ol, the non-steroidal antiestrogen MER25. Acta Crystallogr C. 1993 Mar 15;49 ( Pt 3):500-4. PubMed PMID: 8484922.9: Billiar RB, Rohan R, Henson MC, Smith P, Babischkin J. Regulation of immunoreactive inhibin patterns in baboon pregnancy: maternal, placental, and fetal considerations. J Clin Endocrinol Metab. 1992 Nov;75(5):1345-51. PubMed PMID: 1430097.10: Barkai U, Kidron T, Kraicer PF. Inhibition of decidual induction in rats by clomiphene and tamoxifen. Biol Reprod. 1992 Apr;46(4):733-9. PubMed PMID: 1576272.1

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