232617-15-1|D-Ribose-L-cysteine|(4R)-2-((1R,2R,3R)-1,2,3,4-tetrahydroxybutyl)thiazolidine-4-carboxylic acid|-范德生物科技公司

D-Ribose-L-cysteine

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names：
(4R)-2-((1R,2R,3R)-1,2,3,4-tetrahydroxybutyl)thiazolidine-4-carboxylic acid
CAS号：
232617-15-1
MDL Number：
MF(分子式)： C8H15NO6S MW(分子量)： 253.26
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	D-Ribose-L-cysteine
英文别名	D-Ribose-L-cysteine; Ribcys; J424.013H; Riboceine; D Ribose L cysteine; DRiboseLcysteine;
CAS号	232617-15-1
SMILES	O=C([C@H]1NC([C@H](O)[C@H](O)[C@H](O)CO)SC1)O
Inchi	InChI=1S/C8H15NO6S/c10-1-4(11)5(12)6(13)7-9-3(2-16-7)8(14)15/h3-7,9-13H,1-2H2,(H,14,15)/t3-,4+,5+,6+,7?/m0/s1
InchiKey	AGZXTDUDXXPCMJ-HZYAIORGSA-N
分子式 Formula	C8H15NO6S
分子量 Molecular Weight	253.26
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	D-Ribose-L-cysteine(CAS:232617-15-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	D-Ribose-L-cysteine is a precursor to the antioxidant glutathione.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Falana B, Adeleke O, Orenolu M, Osinubi A, Oyewopo A. Effect of D-ribose-L-cysteine on aluminum induced testicular damage in male Sprague-Dawley rats. JBRA Assist Reprod. 2017 Jun 1;21(2):94-100. doi: 10.5935/1518-0557.20170023. PubMed PMID: 28609275; PubMed Central PMCID: PMC5473701.

[2]Saltman AE. D-ribose-L-cysteine supplementation enhances wound healing in a rodent model. Am J Surg. 2015 Jul;210(1):153-8. doi: 10.1016/j.amjsurg.2014.11.014. Epub 2015 Mar 27. PubMed PMID: 25935230.

[3] Kader T, Porteous CM, Williams MJ, Gieseg SP, McCormick SP. Ribose-cysteine increases glutathione-based antioxidant status and reduces LDL in human lipoprotein(a) mice. Atherosclerosis. 2014 Dec;237(2):725-33. doi: 10.1016/j.atherosclerosis.2014.10.101. Epub 2014 Nov 1. PubMed PMID: 25463112.

[4] Im GY, Kazi S, Thung SN, Perumalswami PV. A maxed-out liver: a case of acute-on-chronic liver failure. Semin Liver Dis. 2011 Nov;31(4):420-6. doi: 10.1055/s-0031-1297930. Epub 2011 Dec 21. PubMed PMID: 22189981.

[5] Jurkowska H, Uchacz T, Roberts J, Wróbel M. Potential therapeutic advantage of ribose-cysteine in the inhibition of astrocytoma cell proliferation. Amino Acids. 2011 Jun;41(1):131-9. doi: 10.1007/s00726-010-0593-4. Epub 2010 Apr 23. PubMed PMID: 20414692.

6: Oz HS, Chen TS, Nagasawa H. Comparative efficacies of 2 cysteine prodrugs and a glutathione delivery agent in a colitis model. Transl Res. 2007 Aug;150(2):122-9. Epub 2007 May 23. PubMed PMID: 17656332; PubMed Central PMCID: PMC1991291.7: Slitt AM, Dominick PK, Roberts JC, Cohen SD. Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion. Basic Clin Pharmacol Toxicol. 2005 Jun;96(6):487-94. PubMed PMID: 15910414.8: Waldren CA, Vannais DB, Ueno AM. A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: counteraction by ascorbate and RibCys but not DMSO. Mutat Res. 2004 Jul 13;551(1-2):255-65. PubMed PMID: 15225598.9: Lenarczyk M, Ueno A, Vannais DB, Kraemer S, Kronenberg A, Roberts JC, Tatsumi K, Hei TK, Waldren CA. The "pro-drug" RibCys decreases the mutagenicity of high-LET radiation in cultured mammalian cells. Radiat Res. 2003 Nov;160(5):579-83. PubMed PMID: 14565824.10: Ueno A, Vannais D, Lenarczyk M, Waldren CA. Ascorbate, added after irradiation, reduces the mutant yield and alters the spectrum of CD59- mutations in A(L) cells irradiated with high LET carbon ions. J Radiat Res. 2002 Dec;43 Suppl:S245-9. PubMed PMID: 12793767.1

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