134381-30-9|Conagenin|(S)-2-((2R,3S,4R)-2,4-dihydroxy-3-methylpentanamido)-3-hydroxy-2-methylpropanoic acid|-范德生物科技公司

Conagenin

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names：
(S)-2-((2R,3S,4R)-2,4-dihydroxy-3-methylpentanamido)-3-hydroxy-2-methylpropanoic acid
CAS号：
134381-30-9
MDL Number：
MF(分子式)： C10H19NO6 MW(分子量)： 249.26
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Conagenin
英文别名	Conagenin;
CAS号	134381-30-9
Inchi	InChI=1S/C10H19NO6/c1-5(6(2)13)7(14)8(15)11-10(3,4-12)9(16)17/h5-7,12-14H,4H2,1-3H3,(H,11,15)(H,16,17)/t5-,6+,7+,10-/m0/s1
InchiKey	GLESHRYLRAOJPS-DHCFDGJBSA-N
分子式 Formula	C10H19NO6
分子量 Molecular Weight	249.26
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Conagenin(CAS:134381-30-9):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Conagenin is a low molecular weight immunomodulator produced by Streptomyces roseosporus.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Jiao XZ, Wang LP, Xiao Q, Xie P, Liang XT. Total synthesis of (+)-conagenin. J Asian Nat Prod Res. 2009;11(3):274-80. doi: 10.1080/10286020902828369. PubMed PMID: 19408153.

[2]Kawatsu M, Yamashita T, Ishizuka M, Takeuchi T. Effect of conagenin on thrombocytopenia induced by antitumor agents in mice. J Antibiot (Tokyo). 1994 Oct;47(10):1123-9. PubMed PMID: 7961162.

[3] Hamada M, Yamamoto S, Moriguchi S, Kishino Y. Phagocytosis of alveolar macrophages after conagenin injection to rats. J Antibiot (Tokyo). 2001 Apr;54(4):349-53. PubMed PMID: 11426659.

[4] Kawatsu M, Yamashita T, Osono M, Ishizuka M, Takeuchi T. T cell activation by conagenin in mice. J Antibiot (Tokyo). 1993 Nov;46(11):1687-91. PubMed PMID: 8270490.

[5] Matsukawa Y, Isobe M, Kotsuki H, Ichikawa Y. Synthesis of (+)-conagenin. J Org Chem. 2005 Jun 24;70(13):5339-41. PubMed PMID: 15960545.

6: Yamashita T, Iijima M, Nakamura H, Isshiki K, Naganawa H, Hattori S, Hamada M, Ishizuka M, Takeuchi T, Iitaka Y. Conagenin, a low molecular weight immunomodulator produced by Streptomyces roseosporus. J Antibiot (Tokyo). 1991 May;44(5):557-9. PubMed PMID: 1905708.7: Kawatsu M, Yamashita T, Ishizuka M, Takeuchi T. Improvement of efficacy of antitumor agents by conagenin. J Antibiot (Tokyo). 1995 Mar;48(3):222-5. PubMed PMID: 7730156.8: Hamada M, Sonotake E, Yamamoto S, Moriguchi S. Conagenin derived from Streptomyces roseosporus enhances macrophage functions. J Antibiot (Tokyo). 1999 Jun;52(6):548-51. PubMed PMID: 10470679.9: Kawatsu M, Yamashita T, Ishizuka M, Takeuchi T. Modulation by conagenin of inflammatory mediator productions in mice given 5-fluorouracil. Anticancer Res. 1997 Mar-Apr;17(2A):917-22. PubMed PMID: 9137428.10: Kawatsu M, Yamashita T, Osono M, Masuda T, Ishizuka M, Takeuchi T. Effect of conagenin in tumor bearing mice. Antitumor activity, generation of effector cells and cytokine production. J Antibiot (Tokyo). 1993 Nov;46(11):1692-8. PubMed PMID: 8270491.1

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