10389-73-8|Clortermine|1-(o-Chlorophenyl)-2-methyl-2-aminopropane|-范德生物科技公司

Clortermine

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names：
1-(o-Chlorophenyl)-2-methyl-2-aminopropane
CAS号：
10389-73-8
MDL Number：
MF(分子式)： C10H14ClN MW(分子量)： 183.679
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Clortermine
英文别名	Clortermine; Clortermina; Clorterminum, Voranil
CAS号	10389-73-8
Inchi	InChI=1S/C10H14ClN/c1-10(2,12)7-8-5-3-4-6-9(8)11/h3-6H,7,12H2,1-2H3
InchiKey	HXCXASJHZQXCKK-UHFFFAOYSA-N
分子式 Formula	C10H14ClN
分子量 Molecular Weight	183.679
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Clortermine(CAS:10389-73-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Clortermine is discontinued (DEA controlled susbtance). It is an anorectic drug of the amphetamine class. It is the 2-chloro analogue of the better known appetite suppressant phentermine, and is the 2-chloro positional isomer of chlorphentermine. Clortermine produces very low rates of self-administration in animals similarly to chlorphentermine, and as a result it likely does not act on dopamine. Instead, it may act as a serotonin and/or norepinephrine releasing agent.
Application1
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警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Foltin RW. Effects of anorectic drugs on the topography of feeding behavior in baboons. J Pharmacol Exp Ther. 1989 Apr;249(1):101-9. PubMed PMID: 2709326.

[2]de la Garza R, Johanson CE. Discriminative stimulus properties of intragastrically administered d-amphetamine and pentobarbital in rhesus monkeys. J Pharmacol Exp Ther. 1987 Dec;243(3):955-62. PubMed PMID: 2891839.

[3] Evans SM, Johanson CE. Amphetamine-like effects of anorectics and related compounds in pigeons. J Pharmacol Exp Ther. 1987 Jun;241(3):817-25. PubMed PMID: 2885408.

[4] Corwin RL, Woolverton WL, Schuster CR, Johanson CE. Anorectics: effects on food intake and self-administration in rhesus monkeys. Alcohol Drug Res. 1987;7(5-6):351-61. PubMed PMID: 3620005.

[5] Griffiths RR, Winger G, Brady JV, Snell JD. Comparison of behavior maintained by infusions of eight phenylethylamines in baboons. Psychopharmacology (Berl). 1976 Nov 24;50(3):251-8. PubMed PMID: 826970.

6: Dykes MH. Evaluation of three anorexiants. Clortermine hydrochloride (voranil), fenfluramine hydrochloride (pondimin), and mazindol (sanorex). JAMA. 1974 Oct 14;230(2):270-2. PubMed PMID: 4606535.

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