35764-59-1|Cismethrin|Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (5-(phenylmethyl)-3-furanyl)methyl ester, (1R,3S)-|-范德生物科技公司

Cismethrin

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names：
Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, (5-(phenylmethyl)-3-furanyl)methyl ester, (1R,3S)-
CAS号：
35764-59-1
MDL Number：
MF(分子式)： C22H26O3 MW(分子量)： 338.45
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Cismethrin
英文别名	Cismethrin; AI 3-27987; AI-3-27987; AI3-27987
CAS号	35764-59-1
SMILES	O=C([C@H]1C(C)(C)[C@H]1/C=C(C)\C)OCC2=COC(CC3=CC=CC=C3)=C2
Inchi	InChI=1S/C22H26O3/c1-15(2)10-19-20(22(19,3)4)21(23)25-14-17-12-18(24-13-17)11-16-8-6-5-7-9-16/h5-10,12-13,19-20H,11,14H2,1-4H3/t19-,20-/m0/s1
InchiKey	VEMKTZHHVJILDY-PMACEKPBSA-N
分子式 Formula	C22H26O3
分子量 Molecular Weight	338.45
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Cismethrin(CAS:35764-59-1):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Cismethrin is a pyrethroid insecticide.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Oliveira EE, Du Y, Nomura Y, Dong K. A residue in the transmembrane segment 6 of domain I in insect and mammalian sodium channels regulate differential sensitivities to pyrethroid insecticides. Neurotoxicology. 2013 Sep;38:42-50. doi: 10.1016/j.neuro.2013.06.00[1]Epub 2013 Jun 10. PubMed PMID: 23764339; PubMed Central PMCID: PMC3773218.

[2]Breckenridge CB, Holden L, Sturgess N, Weiner M, Sheets L, Sargent D, Soderlund DM, Choi JS, Symington S, Clark JM, Burr S, Ray D. Evidence for a separate mechanism of toxicity for the Type I and the Type II pyrethroid insecticides. Neurotoxicology. 2009 Nov;30 Suppl 1:S17-31. doi: 10.1016/j.neuro.2009.09.002. Epub 2009 Sep 18. PubMed PMID: 19766671.

[3] Clark JM, Symington SB. Neurotoxic implications of the agonistic action of CS-syndrome pyrethroids on the N-type Ca(v)2.2 calcium channel. Pest Manag Sci. 2008 Jun;64(6):628-38. doi: 10.1002/ps.1573. PubMed PMID: 18383452.

[4] Wolansky MJ, Harrill JA. Neurobehavioral toxicology of pyrethroid insecticides in adult animals: a critical review. Neurotoxicol Teratol. 2008 Mar-Apr;30(2):55-78. doi: 10.1016/j.ntt.2007.10.005. Epub 2007 Nov 17. Review. PubMed PMID: 18206347.

[5] Clark JM, Symington SB. Pyrethroid action on calcium channels: neurotoxicological implications. Invert Neurosci. 2007 Mar;7(1):3-16. Epub 2007 Feb 9. PubMed PMID: 17294162.

6: Choi JS, Soderlund DM. Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Na v 1.8 sodium channels expressed in Xenopus oocytes. Toxicol Appl Pharmacol. 2006 Mar 15;211(3):233-44. Epub 2005 Jul 26. PubMed PMID: 16051293.7: Choi JS, Soderlund DM. Cyclosporin A and deltamethrin block the downregulation of Nav1.8 sodium channels expressed in Xenopus oocytes. Neurosci Lett. 2004 Sep 9;367(3):389-93. PubMed PMID: 15337272.8: Burr SA, Ray DE. Structure-activity and interaction effects of 14 different pyrethroids on voltage-gated chloride ion channels. Toxicol Sci. 2004 Feb;77(2):341-6. Epub 2003 Dec 2. PubMed PMID: 14657519.9: Soderlun DM, Lee SH. Point mutations in homology domain II modify the sensitivity of rat Nav1.8 sodium channels to the pyrethroid insecticide cismethrin. Neurotoxicology. 2001 Dec;22(6):755-65. PubMed PMID: 11829409.10: Lee SH, Soderlund DM. The V410M mutation associated with pyrethroid resistance in Heliothis virescens reduces the pyrethroid sensitivity of house fly sodium channels expressed in Xenopus oocytes. Insect Biochem Mol Biol. 2001 Jan;31(1):19-29. PubMed PMID: 11102831.1

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