58840-30-5|Chromozym PK|(S)-N-((S)-1-(((S)-1-amino-5-guanidino-1-oxopentan-2-yl)(4-nitrophenyl)amino)-1-oxo-3-phenylpropan-2-yl)-1-benzoylpyrrolidine-2-carboxamide|-范德生物科技公司

Chromozym PK

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names：
(S)-N-((S)-1-(((S)-1-amino-5-guanidino-1-oxopentan-2-yl)(4-nitrophenyl)amino)-1-oxo-3-phenylpropan-2-yl)-1-benzoylpyrrolidine-2-carboxamide
CAS号：
58840-30-5
MDL Number：
MF(分子式)： C33H38N8O6 MW(分子量)： 642.71
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Chromozym PK
英文别名	Chromozym PK;
CAS号	58840-30-5
Inchi	InChI=1S/C33H38N8O6/c34-29(42)27(13-7-19-37-33(35)36)40(24-15-17-25(18-16-24)41(46)47)32(45)26(21-22-9-3-1-4-10-22)38-30(43)28-14-8-20-39(28)31(44)23-11-5-2-6-12-23/h1-6,9-12,15-18,26-28H,7-8,13-14,19-21H2,(H2,34,42)(H,38,43)(H4,35,36,37)/t26-,27-,28-/m0/s1
InchiKey	GAMRKVOQYKERQN-KCHLEUMXSA-N
分子式 Formula	C33H38N8O6
分子量 Molecular Weight	642.71
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Chromozym PK(CAS:58840-30-5):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Chromozym PK is a chromogenic substrate for factor XII assay.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Shibayama Y, Brunnee T, Kaplan AP, Reddigari S. Activation of human Hageman factor (factor XII) in the presence of zinc and phosphate ions. Braz J Med Biol Res. 1994 Aug;27(8):1817-28. PubMed PMID: 7749371.

[2]Nishikawa K, Reddigari SR, Silverberg M, Kuna PB, Yago H, Nagaki Y, Toyomaki Y, Suehiro S, Kaplan AP. Effect of Neurotropin on the activation of the plasma kallikrein-kinin system. Biochem Pharmacol. 1992 Mar 17;43(6):1361-9. PubMed PMID: 1562287.

[3] Tans G, Janssen-Claessen T, Rosing J, Griffin JH. Studies on the effect of serine protease inhibitors on activated contact factors. Application in amidolytic assays for factor XIIa, plasma kallikrein and factor XIa. Eur J Biochem. 1987 May 4;164(3):637-42. PubMed PMID: 3552674.

[4] Nieuw Amerongen AV, Oderkerk CH, Roukema PA. AM1, a glycoprotein from the submandibular glands of the mouse, has esterolytic and amidolytic activities. Biochim Biophys Acta. 1984 May 17;786(3):245-51. PubMed PMID: 6722171.

[5] Kyrle PA, Niessner H, Deutsch E, Lechner K, Korninger C, Mannhalter C. CRM+ severe Fletcher factor deficiency associated with Graves' disease. Haemostasis. 1984;14(4):302-6. PubMed PMID: 6568197.

6: Stürzebecher J, Klessen C, Markwardt F. [Determination of factor XII and plasma prekallikrein with chromozym PK]. Z Med Lab Diagn. 1982 Oct;23(5):306-11. German. PubMed PMID: 6924817.7: Klessen C, Stürzebecher J, Markwardt F. Determination of factor XII in plasma using the kallikrein substrate chromozym PK. Thromb Res. 1982 Mar 15;25(6):501-5. PubMed PMID: 6921902.8: Vogel G, Stürzebecher J, Klessen C, Lauten G. [Use of chromogenic substrates in the clarification of disorders in the early stages of blood coagulation]. Folia Haematol Int Mag Klin Morphol Blutforsch. 1982;109(1):115-20. German. PubMed PMID: 6177592.9: Dick W, Cullmann W, Müller N, Adler K. Factor XII assay with the chromogenic substrate chromozym PK. J Clin Chem Clin Biochem. 1981 Jun;19(6):357-61. PubMed PMID: 6168728.10: Ito R, Statland BE. Centrifugal analysis for plasma kallikrein activity, with use of the chromogenic substrate S-2302. Clin Chem. 1981 Apr;27(4):586-93. PubMed PMID: 6907061.1

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