118395-73-6|Chloroorienticin A|N/A|-范德生物科技公司

Chloroorienticin A

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names：
N/A
CAS号：
118395-73-6
MDL Number：
MF(分子式)： C73H88Cl2N10O26 MW(分子量)： 1592.45
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Chloroorienticin A
英文别名	Chloroorienticin A; A82846B; A 82846B; A-82846B;
CAS号	118395-73-6
SMILES	O=C([C@H](NC([C@@H](CC(C)C)NC)=O)[C@@H](C1=CC(Cl)=C(OC2=CC3=CC(OC4=C(Cl)C=C([C@H]([C@@H]5N6)O[C@@H]7O[C@@H](C)[C@H](O)[C@](N)(C)C7)C=C4)=C2O[C@H]8[C@H](O[C@@H]9O[C@@H](C)[C@H](O)[C@@](C)(N)C9)[C@H](O)[C@H](O)[C@@H](CO)O8)C=C1)O)N[C@@H](CC(N)=O)C(N[C@H]3C(N[C@H](C%10=CC(C%11=C(O)C=C(C=C%11[C@H](NC5=O)C(O)=O)O)=C(O)C=C%10)C6=O)=O)=O
Inchi	InChI=1S/C73H88Cl2N10O26/c1-26(2)14-38(79-7)64(96)84-54-56(91)30-9-12-42(36(74)16-30)106-44-18-32-19-45(60(44)111-71-61(58(93)57(92)46(25-86)108-71)110-49-24-73(6,78)63(95)28(4)105-49)107-43-13-10-31(17-37(43)75)59(109-48-23-72(5,77)62(94)27(3)104-48)55-69(101)83-53(70(102)103)35-20-33(87)21-41(89)50(35)34-15-29(8-11-40(34)88)51(66(98)85-55)82-67(99)52(32)81-65(97)39(22-47(76)90)80-68(54)100/h8-13,15-21,26-28,38-39,46,48-49,51-59,61-63,71,79,86-89,91-95H,14,22-25,77-78H2,1-7H3,(H2,76,90)(H,80,100)(H,81,97)(H,82,99)(H,83,101)(H,84,96)(H,85,98)(H,102,103)/t27-,28-,38+,39-,46+,48-,49-,51+,52+,53-,54+,55-,56+,57+,58+,59+,61+,62-,63-,71-,72-,73-/m0/s1
InchiKey	XJHXLMVKYIVZTE-ZUDYGFIZSA-N
分子式 Formula	C73H88Cl2N10O26
分子量 Molecular Weight	1592.45
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Chloroorienticin A(CAS:118395-73-6):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Chloroorienticin A is a glycopeptide antibiotic.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Allen NE, LeTourneau DL, Hobbs JN Jr, Thompson RC. Hexapeptide derivatives of glycopeptide antibiotics: tools for mechanism of action studies. Antimicrob Agents Chemother. 2002 Aug;46(8):2344-8. PubMed PMID: 12121903; PubMed Central PMCID: PMC127376.

[2]Pavlov AIu, Preobrazhenskaia MN. [Chemical modification of glycopeptide antibiotics]. Bioorg Khim. 1998 Sep;24(9):644-62. Review. Russian. PubMed PMID: 9813730.

[3] Rodriguez MJ, Snyder NJ, Zweifel MJ, Wilkie SC, Stack DR, Cooper RD, Nicas TI, Mullen DL, Butler TF, Thompson RC. Novel glycopeptide antibiotics: N-alkylated derivatives active against vancomycin-resistant enterococci. J Antibiot (Tokyo). 1998 Jun;51(6):560-9. PubMed PMID: 9711219.

[4] LeTourneau DL, Allen NE. Use of capillary electrophoresis to measure dimerization of glycopeptide antibiotics. Anal Biochem. 1997 Mar 1;246(1):62-6. PubMed PMID: 9056183.

[5] Allen NE, LeTourneau DL, Hobbs JN Jr. Molecular interactions of a semisynthetic glycopeptide antibiotic with D-alanyl-D-alanine and D-alanyl-D-lactate residues. Antimicrob Agents Chemother. 1997 Jan;41(1):66-71. PubMed PMID: 8980756; PubMed Central PMCID: PMC163661.

6: Nicas TI, Mullen DL, Flokowitsch JE, Preston DA, Snyder NJ, Zweifel MJ, Wilkie SC, Rodriguez MJ, Thompson RC, Cooper RD. Semisynthetic glycopeptide antibiotics derived from LY264826 active against vancomycin-resistant enterococci. Antimicrob Agents Chemother. 1996 Sep;40(9):2194-9. PubMed PMID: 8878606; PubMed Central PMCID: PMC163498.7: Cooper RD, Snyder NJ, Zweifel MJ, Staszak MA, Wilkie SC, Nicas TI, Mullen DL, Butler TF, Rodriguez MJ, Huff BE, Thompson RC. Reductive alkylation of glycopeptide antibiotics: synthesis and antibacterial activity. J Antibiot (Tokyo). 1996 Jun;49(6):575-81. PubMed PMID: 8698642.8: Linsdell H, Toiron C, Bruix M, Rivas G, Menéndez M. Dimerization of A82846B, vancomycin and ristocetin: influence on antibiotic complexation with cell wall model peptides. J Antibiot (Tokyo). 1996 Feb;49(2):181-93. PubMed PMID: 8621360.9: Prowse WG, Kline AD, Skelton MA, Loncharich RJ. Conformation of A82846B, a glycopeptide antibiotic, complexed with its cell wall fragment: an asymmetric homodimer determined using NMR spectroscopy. Biochemistry. 1995 Jul 25;34(29):9632-44. PubMed PMID: 7626632.10: Ena J, Houston A, Wenzel RP, Jones RN. Trends in gram-positive bloodstream organism resistance: a seven-year audit of five glycopeptides and other drugs at a large university hospital. J Chemother. 1993 Feb;5(1):17-21. PubMed PMID: 8459260.1

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