934628-27-0|CG-400549|1-(3-amino-2-methylbenzyl)-4-(2-(thiophen-2-yl)ethoxy)pyridin-2(1H)-one|-范德生物科技公司

CG-400549

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names：
1-(3-amino-2-methylbenzyl)-4-(2-(thiophen-2-yl)ethoxy)pyridin-2(1H)-one
CAS号：
934628-27-0
MDL Number：
MF(分子式)： C19H20N2O2S MW(分子量)： 340.441
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

货品编码	规格	纯度	价格 (¥)	现价(¥)	特价(¥)	库存描述	数量	总计 (¥)
FMK13279-100mg	100mg	>98%	¥ 0.00	¥ 0.00		Get quote	- +	¥ 0.00

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中文别名	CG-400549
英文别名	CG-400549; CG 400549; CG400549; CG-0549; CG 0549; CG0549.
CAS号	934628-27-0
Inchi	InChI=1S/C19H20N2O2S/c1-14-15(4-2-6-18(14)20)13-21-9-7-16(12-19(21)22)23-10-8-17-5-3-11-24-17/h2-7,9,11-12H,8,10,13,20H2,1H3
InchiKey	YCLREGRRHGLOAK-UHFFFAOYSA-N
分子式 Formula	C19H20N2O2S
分子量 Molecular Weight	340.441
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	CG-400549(CAS:934628-27-0):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	CG-400549, also known as CG-0549, is an enoyl-(acyl-carrier protein) reductase fabl inhibitor potentially for the treatment of compcolicated acute. CG400549 had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin. Among 203 strains of Staphylococcus aureus, the MICs of CG400549 were 0.06 to 1.0 microg/ml, with MIC(50) and MIC(90) values of 0.25 microg/ml each. All strains were susceptible to linezolid and quinupristin-dalfopristin (MICs, 0.25 to 2.0 microg/ml).
Application1
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警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Kim BY, Sohn YT. Solid state of CG-400549, a novel FabI inhibitor:characterization, dissolution, transformation. Arch Pharm Res. 2011May;34(5):775-9. doi: 10.1007/s12272-011-0511-7. Epub 2011 Jun 9. PubMed PMID:21656363.

[2]Bogdanovich T, Clark C, Kosowska-Shick K, Dewasse B, McGhee P, Appelbaum PC.Antistaphylococcal activity of CG400549, a new experimental FabI inhibitor,compared with that of other agents. Antimicrob Agents Chemother. 2007Nov;51(11):4191-5. Epub 2007 Sep 17. PubMed PMID: 17875997; PubMed Central PMCID:PMC2151435.

[3] Yum JH, Kim CK, Yong D, Lee K, Chong Y, Kim CM, Kim JM, Ro S, Cho JM. In vitroactivities of CG400549, a novel FabI inhibitor, against recently isolatedclinical staphylococcal strains in Korea. Antimicrob Agents Chemother. 2007Jul;51(7):2591-3. Epub 2007 Apr 9. PubMed PMID: 17420210; PubMed Central PMCID:PMC1913239.

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