25633-33-4|Cerberin|3-((4-O-Acetyl-6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy)-14-hydroxy-(3beta,5beta)-card-20(22)-enolide|-范德生物科技公司

Cerberin

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names：
3-((4-O-Acetyl-6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy)-14-hydroxy-(3beta,5beta)-card-20(22)-enolide
CAS号：
25633-33-4
MDL Number：
MF(分子式)： C32H48O9 MW(分子量)： 576.727
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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询价

中文别名	Cerberin
英文别名	Cerberin; Acetylneriifolin; Neriifolin-monoacetat; Pveneniferin
CAS号	25633-33-4
Inchi	InChI=1S/C32H48O9/c1-17-27(40-18(2)33)28(37-5)26(35)29(39-17)41-21-8-11-30(3)20(15-21)6-7-24-23(30)9-12-31(4)22(10-13-32(24,31)36)19-14-25(34)38-16-19/h14,17,20-24,26-29,35-36H,6-13,15-16H2,1-5H3/t17-,20+,21-,22+,23-,24+,26-,27-,28-,29-,30-,31+,32-/m0/s1
InchiKey	WSAWDNPGMCYQEI-IGPZFFOWSA-N
分子式 Formula	C32H48O9
分子量 Molecular Weight	576.727
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Cerberin(CAS:25633-33-4):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Cerberin is a cardiac glycoside that exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Menezes RG, Usman MS, Hussain SA, Madadin M, Siddiqi TJ, Fatima H, Ram P, Pasha SB, Senthilkumaran S, Fatima TQ, Luis SA. Cerbera odollam toxicity: A review. J Forensic Leg Med. 2018 Aug;58:113-116. doi: 10.1016/j.jflm.2018.05.007. Epub 2018 May 9. Review. PubMed PMID: 29778924.

[2]Carlier J, Guitton J, Bévalot F, Fanton L, Gaillard Y. The principal toxic glycosidic steroids in Cerbera manghas L. seeds: identification of cerberin, neriifolin, tanghinin and deacetyltanghinin by UHPLC-HRMS/MS, quantification by UHPLC-PDA-MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jul 1;96

2:1-8. doi: 10.1016/j.jchromb.2014.05.014. Epub 2014 May 17. PubMed PMID: 24878878.

[4]LANG HY, SUN NJ. [STUDIES ON THE CARDIAC GLYCOSIDES OF THEVETIA PERUVIANA MERR. SYN. THEVETIA NERIIFOLIA JUSS. II. ISOLATION AND IDENTIFICATION OF CERBERIN, RUVOSIDE AND A NEW CARDIAC GLYCOSIDE--PERUSITIN]. Yao Xue Xue Bao. 1964 Jul;11:464-72. Chinese. PubMed PMID: 14202490.

[5] Alzabib AA, Abobakr Y, Al-Sarar AS, Hussein HI, Basudan OA, El-Gamal AA, Abdel-Kader MS, El Komy MH. Molluscicidal activity of cardiac glycosides isolated from Adenium obesum. Pest Manag Sci. 2019 Mar 5. doi: 10.1002/ps.5388. [Epub ahead of print] PubMed PMID: 30838743.

5: Yen YC. [Cardiac effects of cerberin]. Zhonghua Yi Xue Za Zhi. 1974;(10):642-5, 181. Chinese. PubMed PMID: 4434780.

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