14016-29-6|Averufin|2,6-Epoxy-2H-anthra(2,3-b)oxocin-8,13-dione, 3,4,5,6-tetrahydro-2-methyl-7,9,11-trihydroxy-|-范德生物科技公司

Averufin

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names：
2,6-Epoxy-2H-anthra(2,3-b)oxocin-8,13-dione, 3,4,5,6-tetrahydro-2-methyl-7,9,11-trihydroxy-
CAS号：
14016-29-6
MDL Number：
MF(分子式)： C20H16O7 MW(分子量)： 368.34
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Averufin
英文别名	Averufin;
CAS号	14016-29-6
SMILES	O=C(C1=C2C=C(O)C=C1O)C3=C(C=C4OC(O5)(C)CCCC5C4=C3O)C2=O
Inchi	InChI=1S/C20H16O7/c1-20-4-2-3-12(26-20)16-13(27-20)7-10-15(19(16)25)18(24)14-9(17(10)23)5-8(21)6-11(14)22/h5-7,12,21-22,25H,2-4H2,1H3
InchiKey	RYFFZJHGQCKWMV-UHFFFAOYSA-N
分子式 Formula	C₂₀H₁₆O₇
分子量 Molecular Weight	368.34
闪点 FP
熔点 Melting point
沸点 Boiling point
Polarizability极化度
密度 Density
蒸汽压 Vapor Pressure
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Averufin(CAS:14016-29-6):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Averufin is has antifungal activity.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Liu K, Zheng Y, Miao C, Xiong Z, Xu L, Guan H, Yang Y, Zhao L. The antifungal metabolites obtained from the rhizospheric Aspergillus sp. YIM PH30001 against pathogenic fungi of Panax notoginseng. Nat Prod Res. 2014;28(24):2334-7. doi: 10.1080/14786419.2014.93594[1]Epub 2014 Jul 15. PubMed PMID: 25022791.

[2]Wu CJ, Li CW, Cui CB. Seven new and two known lipopeptides as well as five known polyketides: the activated production of silent metabolites in a marine-derived fungus by chemical mutagenesis strategy using diethyl sulphate. Mar Drugs. 2014 Mar 28;12(4):1815-38. doi: 10.3390/md12041815. PubMed PMID: 24686557; PubMed Central PMCID: PMC4012460.

[3] Shao C, Wang C, Wei M, Li S, She Z, Gu Y, Lin Y. Structural and spectral assignments of six anthraquinone derivatives from the mangrove fungus (ZSUH-36). Magn Reson Chem. 2008 Sep;46(9):886-9. doi: 10.1002/mrc.2266. PubMed PMID: 18615624.

[4] Sakuno E, Kameyama M, Nakajima H, Yabe K. Purification and gene cloning of a dehydrogenase from Lactobacillus brevis that catalyzes a reaction involved in aflatoxin biosynthesis. Biosci Biotechnol Biochem. 2008 Mar;72(3):724-34. Epub 2008 Mar 7. PubMed PMID: 18323645.

[5] Shier WT, Lao Y, Steele TW, Abbas HK. Yellow pigments used in rapid identification of aflatoxin-producing Aspergillus strains are anthraquinones associated with the aflatoxin biosynthetic pathway. Bioorg Chem. 2005 Dec;33(6):426-38. Epub 2005 Nov 2. PubMed PMID: 16260026.

6: Wen Y, Hatabayashi H, Arai H, Kitamoto HK, Yabe K. Function of the cypX and moxY genes in aflatoxin biosynthesis in Aspergillus parasiticus. Appl Environ Microbiol. 2005 Jun;71(6):3192-8. PubMed PMID: 15933021; PubMed Central PMCID: PMC1151844.7: Sakuno E, Wen Y, Hatabayashi H, Arai H, Aoki C, Yabe K, Nakajima H. Aspergillus parasiticus cyclase catalyzes two dehydration steps in aflatoxin biosynthesis. Appl Environ Microbiol. 2005 Jun;71(6):2999-3006. PubMed PMID: 15932995; PubMed Central PMCID: PMC1151850.8: Yabe K, Nakajima H. Enzyme reactions and genes in aflatoxin biosynthesis. Appl Microbiol Biotechnol. 2004 Jun;64(6):745-55. Epub 2004 Mar 12. Review. PubMed PMID: 15022028.9: Sakuno E, Yabe K, Nakajima H. Involvement of two cytosolic enzymes and a novel intermediate, 5'-oxoaverantin, in the pathway from 5'-hydroxyaverantin to averufin in aflatoxin biosynthesis. Appl Environ Microbiol. 2003 Nov;69(11):6418-26. PubMed PMID: 14602595; PubMed Central PMCID: PMC262255.10: Maskey RP, Grün-Wollny I, Laatsch H. Isolation, structure elucidation and biological activity of 8-O-methylaverufin and 1,8-O-dimethylaverantin as new antifungal agents from Penicillium chrysogenum. J Antibiot (Tokyo). 2003 May;56(5):459-63. PubMed PMID: 12870811.1

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