112945-21-8|Amphidinolide C|(1S,2R,6S,7R,9R,10R,11R,15R,16S,19S,23R,E)-10,11,16-trihydroxy-2-((S,1E,3E)-5-hydroxy-4-methyl-6-methylenedeca-1,3-dien-1-yl)-7,14,15,19-tetramethyl-12-methylene-3,26,27-trioxatricyclo[21.2.1.16,9]heptacos-13-ene-4,18,21-trione|-范德生物科技公司

Amphidinolide C

NMR下载 COA and HPLC MSDS下载
names：
(1S,2R,6S,7R,9R,10R,11R,15R,16S,19S,23R,E)-10,11,16-trihydroxy-2-((S,1E,3E)-5-hydroxy-4-methyl-6-methylenedeca-1,3-dien-1-yl)-7,14,15,19-tetramethyl-12-methylene-3,26,27-trioxatricyclo[21.2.1.16,9]heptacos-13-ene-4,18,21-trione
CAS号：
112945-21-8
MDL Number：
MF(分子式)： C41H62O10 MW(分子量)： 714.94
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文别名	Amphidinolide C
英文别名	Amphidinolide C
CAS号	112945-21-8
Inchi	InChI=1S/C41H62O10/c1-9-10-12-23(2)39(46)24(3)13-11-14-34-35-16-15-31(49-35)20-30(42)18-26(5)32(43)21-33(44)29(8)25(4)17-28(7)40(47)41(48)37-19-27(6)36(50-37)22-38(45)51-34/h11,13-14,17,26-27,29,31,33-37,39-41,44,46-48H,2,7,9-10,12,15-16,18-22H2,1,3-6,8H3/b14-11+,24-13+,25-17+/t26-,27+,29+,31+,33-,34+,35-,36-,37+,39-,40+,41-/m0/s1
InchiKey	RNKCEFQNDOJBLW-IEBOKVSHSA-N
分子式 Formula	C41H62O10
分子量 Molecular Weight	714.94
溶解度Solubility
性状	Solid powder
储藏条件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

产品说明	Amphidinolide C(CAS:112945-21-8):仅限应用于工业或者科学研究过程中非医疗目的，不应用于人类或动物的临床诊断以及治过程疗，该产品非药用，非食用。
Introduction	Amphidinolide C is a potent cytotoxic 25-membered macrolide from marine dinoflagellate Amphidinium sp.
Application1
Application2
Application3

警示图
危险性	Warning
危险性警示
安全声明
安全防护
备注

[1]Morra NA, Pagenkopf BL. Gram scale synthesis of the C(18)-C(34) fragment of amphidinolide C. Org Lett. 2011 Feb 18;13(4):572-5. doi: 10.1021/ol1030074. Epub 2011 Jan 2[1]PubMed PMID: 21254755.

[2]Clark JS, Yang G, Osnowski AP. Synthesis of the C-18-C-34 fragment of amphidinolides C, C2, and C3. Org Lett. 2013 Apr 5;15(7):1464-7. doi: 10.1021/ol400482j. Epub 2013 Mar 25. PubMed PMID: 23527614.

[3] Wu D, Forsyth CJ. Syntheses of the C1-C14 and C15-C25 fragments of amphidinolide C. Org Lett. 2013 Mar 15;15(6):1178-81. doi: 10.1021/ol303515h. Epub 2013 Feb 26. PubMed PMID: 23441846.

[4] Roy S, Spilling CD. Synthesis of the C(18)-C(34) fragment of amphidinolide C and the C(18)-C(29) fragment of amphidinolide F. Org Lett. 2010 Nov 19;12(22):5326-9. doi: 10.1021/ol102345v. Epub 2010 Oct 28. PubMed PMID: 21028791; PubMed Central PMCID: PMC2981351.

[5] Clark JS, Yang G, Osnowski AP. Synthesis of the C-1-C-17 fragment of amphidinolides C, C2, C3, and F. Org Lett. 2013 Apr 5;15(7):1460-3. doi: 10.1021/ol4004838. Epub 2013 Mar 25. PubMed PMID: 23527702.

6: Bates RH, Shotwell JB, Roush WR. Stereoselective syntheses of the C(1)-C(9) fragment of amphidinolide C. Org Lett. 2008 Oct 2;10(19):4343-6. doi: 10.1021/ol801852j. Epub 2008 Sep 11. PubMed PMID: 18783230; PubMed Central PMCID: PMC2650083.7: Mahapatra S, Carter RG. Exploiting hidden symmetry in natural products: total syntheses of amphidinolides C and F. J Am Chem Soc. 2013 Jul 24;135(29):10792-803. doi: 10.1021/ja404796n. Epub 2013 Jul 11. PubMed PMID: 23845005; PubMed Central PMCID: PMC3786714.8: Kubota T, Tsuda M, Kobayashi J. Absolute stereochemistry of amphidinolide C. Org Lett. 2001 May 3;3(9):1363-6. PubMed PMID: 11348235.9: Ferrié L, Figadère B. Efficient synthesis of the C(1)-C(9) fragment of amphidinolides C, C2, and F. Org Lett. 2010 Nov 5;12(21):4976-9. doi: 10.1021/ol1021228. PubMed PMID: 20882983.10: Paudyal MP, Rath NP, Spilling CD. A formal synthesis of the C1-C9 fragment of amphidinolide C employing the Tamaru reaction. Org Lett. 2010 Jul 2;12(13):2954-7. doi: 10.1021/ol100959a. PubMed PMID: 20527780; PubMed Central PMCID: PMC2896498.1

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